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CMV and HSV Pneumonia After Immunosuppressive Agents for Treatment of Cytokine Release Syndrome Due to Chimeric Antigen Receptor-modified T (CAR-T)-Cell Immunotherapy.

Publication ,  Journal Article
Heldman, MR; Ma, J; Gauthier, J; O'Hara, RA; Cowan, AJ; Yoke, LM; So, L; Gulleen, E; Duke, ER; Liu, C; Turtle, CJ; Hill, JA
Published in: J Immunother
November 2021

Pneumonia due to cytomegalovirus and herpes simplex virus-1 caused substantial morbidity after hematopoietic cell transplantation before the institution of preventative approaches. End-organ disease from herpesviruses is poorly described after chimeric antigen receptor-modified T-cell immunotherapy. We report 2 cases of cytomegalovirus pneumonia and 1 case of herpes simplex virus-1 gingivostomatitis, esophagitis, and pneumonia after chimeric antigen receptor-modified T-cell immunotherapy for the treatment of hematologic malignancies.

Duke Scholars

Published In

J Immunother

DOI

EISSN

1537-4513

Publication Date

November 2021

Volume

44

Issue

9

Start / End Page

351 / 354

Location

United States

Related Subject Headings

  • Simplexvirus
  • Receptors, Chimeric Antigen
  • Pneumonia
  • Immunotherapy, Adoptive
  • Immunotherapy
  • Immunosuppressive Agents
  • Immunology
  • Humans
  • Cytomegalovirus Infections
  • Cytokine Release Syndrome
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Heldman, M. R., Ma, J., Gauthier, J., O’Hara, R. A., Cowan, A. J., Yoke, L. M., … Hill, J. A. (2021). CMV and HSV Pneumonia After Immunosuppressive Agents for Treatment of Cytokine Release Syndrome Due to Chimeric Antigen Receptor-modified T (CAR-T)-Cell Immunotherapy. J Immunother, 44(9), 351–354. https://doi.org/10.1097/CJI.0000000000000388
Heldman, Madeleine R., Jimmy Ma, Jordan Gauthier, Riley A. O’Hara, Andrew J. Cowan, Leah M. Yoke, Lisa So, et al. “CMV and HSV Pneumonia After Immunosuppressive Agents for Treatment of Cytokine Release Syndrome Due to Chimeric Antigen Receptor-modified T (CAR-T)-Cell Immunotherapy.J Immunother 44, no. 9 (November 2021): 351–54. https://doi.org/10.1097/CJI.0000000000000388.
Heldman, Madeleine R., et al. “CMV and HSV Pneumonia After Immunosuppressive Agents for Treatment of Cytokine Release Syndrome Due to Chimeric Antigen Receptor-modified T (CAR-T)-Cell Immunotherapy.J Immunother, vol. 44, no. 9, Nov. 2021, pp. 351–54. Pubmed, doi:10.1097/CJI.0000000000000388.
Heldman MR, Ma J, Gauthier J, O’Hara RA, Cowan AJ, Yoke LM, So L, Gulleen E, Duke ER, Liu C, Turtle CJ, Hill JA. CMV and HSV Pneumonia After Immunosuppressive Agents for Treatment of Cytokine Release Syndrome Due to Chimeric Antigen Receptor-modified T (CAR-T)-Cell Immunotherapy. J Immunother. 2021 Nov;44(9):351–354.

Published In

J Immunother

DOI

EISSN

1537-4513

Publication Date

November 2021

Volume

44

Issue

9

Start / End Page

351 / 354

Location

United States

Related Subject Headings

  • Simplexvirus
  • Receptors, Chimeric Antigen
  • Pneumonia
  • Immunotherapy, Adoptive
  • Immunotherapy
  • Immunosuppressive Agents
  • Immunology
  • Humans
  • Cytomegalovirus Infections
  • Cytokine Release Syndrome