Scholars@Duke

Cerebral Venous Thrombosis: Reviewing Pathophysiology, Diagnosis, and Treatment Strategies

Publication ,  Journal Article
O'Keefe, YA; Kranz, PG; Dombrowski, KE; Kolls, BJ; James, ML
Published in: Journal of Neuroanaesthesiology and Critical Care
June 2019
Published version (DOI) Publisher Link

This review discusses cerebral venous thrombosis (CVT), including diagnosis and treatment strategies, a rare class of stroke that, if unrecognized or untreated, can have devastating effects. Thrombosis of one or many cerebral veins leads to propagation of thrombosis and impaired cerebral venous drainage. Diagnosis is made using a combination of history and imaging, particularly computed tomography (CT) venogram, which demonstrates thrombosis. Currently, acute treatment consists of heparin infusion with transition to long-term oral anticoagulation. Further research, especially on prevention, endovascular therapy, and the role of newer anticoagulants (direct oral anticoagulants [DOACs]) is necessary and ongoing.

Duke Scholars

Michael Lucas James
Author Michael Lucas James Anesthesiology, Neuroanesthesia

Published In

Journal of Neuroanaesthesiology and Critical Care

DOI

10.1055/s-0039-1692023

EISSN

2348-926X

ISSN

2348-0548

Publication Date

June 2019

Volume

06

Issue

02

Start / End Page

140 / 144

Publisher

Georg Thieme Verlag KG
 

Citation

APA
Chicago
ICMJE
MLA
NLM
O’Keefe, Y. A., Kranz, P. G., Dombrowski, K. E., Kolls, B. J., & James, M. L. (2019). Cerebral Venous Thrombosis: Reviewing Pathophysiology, Diagnosis, and Treatment Strategies. Journal of Neuroanaesthesiology and Critical Care, 06(02), 140–144. https://doi.org/10.1055/s-0039-1692023
O’Keefe, Yasmin A., Peter G. Kranz, Keith E. Dombrowski, Brad J. Kolls, and Michael L. James. “Cerebral Venous Thrombosis: Reviewing Pathophysiology, Diagnosis, and Treatment Strategies.” Journal of Neuroanaesthesiology and Critical Care 06, no. 02 (June 2019): 140–44. https://doi.org/10.1055/s-0039-1692023.
O’Keefe YA, Kranz PG, Dombrowski KE, Kolls BJ, James ML. Cerebral Venous Thrombosis: Reviewing Pathophysiology, Diagnosis, and Treatment Strategies. Journal of Neuroanaesthesiology and Critical Care. 2019 Jun;06(02):140–4.
O’Keefe, Yasmin A., et al. “Cerebral Venous Thrombosis: Reviewing Pathophysiology, Diagnosis, and Treatment Strategies.” Journal of Neuroanaesthesiology and Critical Care, vol. 06, no. 02, Georg Thieme Verlag KG, June 2019, pp. 140–44. Crossref, doi:10.1055/s-0039-1692023.
O’Keefe YA, Kranz PG, Dombrowski KE, Kolls BJ, James ML. Cerebral Venous Thrombosis: Reviewing Pathophysiology, Diagnosis, and Treatment Strategies. Journal of Neuroanaesthesiology and Critical Care. Georg Thieme Verlag KG; 2019 Jun;06(02):140–144.

Published In

Journal of Neuroanaesthesiology and Critical Care

DOI

10.1055/s-0039-1692023

EISSN

2348-926X

ISSN

2348-0548

Publication Date

June 2019

Volume

06

Issue

02

Start / End Page

140 / 144

Publisher

Georg Thieme Verlag KG