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Are We Focused on the Wrong Early Postoperative Quality Metrics? Optimal Realignment Outweighs Perioperative Risk in Adult Spinal Deformity Surgery.

Publication ,  Journal Article
Passias, PG; Williamson, TK; Mir, JM; Smith, JS; Lafage, V; Lafage, R; Line, B; Daniels, AH; Gum, JL; Schoenfeld, AJ; Hamilton, DK; Scheer, JK ...
Published in: J Clin Med
August 26, 2023

BACKGROUND: While reimbursement is centered on 90-day outcomes, many patients may still achieve optimal, long-term outcomes following adult spinal deformity (ASD) surgery despite transient short-term complications. OBJECTIVE: Compare long-term clinical success and cost-utility between patients achieving optimal realignment and suboptimally aligned peers. STUDY DESIGN/SETTING: Retrospective cohort study of a prospectively collected multicenter database. METHODS: ASD patients with two-year (2Y) data included. Groups were propensity score matched (PSM) for age, frailty, body mass index (BMI), Charlson Comorbidity Index (CCI), and baseline deformity. Optimal radiographic criteria are defined as meeting low deformity in all three (Scoliosis Research Society) SRS-Schwab parameters or being proportioned in Global Alignment and Proportionality (GAP). Cost-per-QALY was calculated for each time point. Multivariable logistic regression analysis and ANCOVA (analysis of covariance) adjusting for baseline disability and deformity (pelvic incidence (PI), pelvic incidence minus lumbar lordosis (PI-LL)) were used to determine the significance of surgical details, complications, clinical outcomes, and cost-utility. RESULTS: A total of 930 patients were considered. Following PSM, 253 "optimal" (O) and 253 "not optimal" (NO) patients were assessed. The O group underwent more invasive procedures and had more levels fused. Analysis of complications by two years showed that the O group suffered less overall major (38% vs. 52%, p = 0.021) and major mechanical complications (12% vs. 22%, p = 0.002), and less reoperations (23% vs. 33%, p = 0.008). Adjusted analysis revealed O patients more often met MCID (minimal clinically important difference) in SF-36 PCS, SRS-22 Pain, and Appearance. Cost-utility-adjusted analysis determined that the O group generated better cost-utility by one year and maintained lower overall cost and costs per QALY (both p < 0.001) at two years. CONCLUSIONS: Fewer late complications (mechanical and reoperations) are seen in optimally aligned patients, leading to better long-term cost-utility overall. Therefore, the current focus on avoiding short-term complications may be counterproductive, as achieving optimal surgical correction is critical for long-term success.

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Published In

J Clin Med

DOI

ISSN

2077-0383

Publication Date

August 26, 2023

Volume

12

Issue

17

Location

Switzerland

Related Subject Headings

  • 32 Biomedical and clinical sciences
  • 1103 Clinical Sciences
 

Citation

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Passias, P. G., Williamson, T. K., Mir, J. M., Smith, J. S., Lafage, V., Lafage, R., … On Behalf Of The International Spine Study Group. (2023). Are We Focused on the Wrong Early Postoperative Quality Metrics? Optimal Realignment Outweighs Perioperative Risk in Adult Spinal Deformity Surgery. J Clin Med, 12(17). https://doi.org/10.3390/jcm12175565
Passias, Peter G., Tyler K. Williamson, Jamshaid M. Mir, Justin S. Smith, Virginie Lafage, Renaud Lafage, Breton Line, et al. “Are We Focused on the Wrong Early Postoperative Quality Metrics? Optimal Realignment Outweighs Perioperative Risk in Adult Spinal Deformity Surgery.J Clin Med 12, no. 17 (August 26, 2023). https://doi.org/10.3390/jcm12175565.
Passias PG, Williamson TK, Mir JM, Smith JS, Lafage V, Lafage R, et al. Are We Focused on the Wrong Early Postoperative Quality Metrics? Optimal Realignment Outweighs Perioperative Risk in Adult Spinal Deformity Surgery. J Clin Med. 2023 Aug 26;12(17).
Passias, Peter G., et al. “Are We Focused on the Wrong Early Postoperative Quality Metrics? Optimal Realignment Outweighs Perioperative Risk in Adult Spinal Deformity Surgery.J Clin Med, vol. 12, no. 17, Aug. 2023. Pubmed, doi:10.3390/jcm12175565.
Passias PG, Williamson TK, Mir JM, Smith JS, Lafage V, Lafage R, Line B, Daniels AH, Gum JL, Schoenfeld AJ, Hamilton DK, Soroceanu A, Scheer JK, Eastlack R, Mundis GM, Diebo B, Kebaish KM, Hostin RA, Gupta MC, Kim HJ, Klineberg EO, Ames CP, Hart RA, Burton DC, Schwab FJ, Shaffrey CI, Bess S, On Behalf Of The International Spine Study Group. Are We Focused on the Wrong Early Postoperative Quality Metrics? Optimal Realignment Outweighs Perioperative Risk in Adult Spinal Deformity Surgery. J Clin Med. 2023 Aug 26;12(17).

Published In

J Clin Med

DOI

ISSN

2077-0383

Publication Date

August 26, 2023

Volume

12

Issue

17

Location

Switzerland

Related Subject Headings

  • 32 Biomedical and clinical sciences
  • 1103 Clinical Sciences