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Cell type-specific chromatin topology and gene regulation.

Publication ,  Journal Article
Phanstiel, DH; Wang, GG
Published in: Trends Genet
May 2022

Chromatin structure is critically involved in gene regulation and cell fate determination. How this structure is established and maintained in distinct, terminally differentiated cells remains elusive. Winick-Ng et al. address this puzzle by applying immunoGAM in different brain cell types and reveal cell type-specific chromatin topologies, long gene decompaction, and the involvement of transcription factors (TFs).

Duke Scholars

Published In

Trends Genet

DOI

ISSN

0168-9525

Publication Date

May 2022

Volume

38

Issue

5

Start / End Page

413 / 415

Location

England

Related Subject Headings

  • Transcription Factors
  • Gene Expression Regulation
  • Developmental Biology
  • Chromosomes
  • Chromatin
  • 42 Health sciences
  • 32 Biomedical and clinical sciences
  • 31 Biological sciences
  • 11 Medical and Health Sciences
  • 06 Biological Sciences
 

Citation

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Chicago
ICMJE
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Phanstiel, D. H., & Wang, G. G. (2022). Cell type-specific chromatin topology and gene regulation. Trends Genet, 38(5), 413–415. https://doi.org/10.1016/j.tig.2022.02.008
Phanstiel, Douglas H., and Gang Greg Wang. “Cell type-specific chromatin topology and gene regulation.Trends Genet 38, no. 5 (May 2022): 413–15. https://doi.org/10.1016/j.tig.2022.02.008.
Phanstiel DH, Wang GG. Cell type-specific chromatin topology and gene regulation. Trends Genet. 2022 May;38(5):413–5.
Phanstiel, Douglas H., and Gang Greg Wang. “Cell type-specific chromatin topology and gene regulation.Trends Genet, vol. 38, no. 5, May 2022, pp. 413–15. Pubmed, doi:10.1016/j.tig.2022.02.008.
Phanstiel DH, Wang GG. Cell type-specific chromatin topology and gene regulation. Trends Genet. 2022 May;38(5):413–415.
Journal cover image

Published In

Trends Genet

DOI

ISSN

0168-9525

Publication Date

May 2022

Volume

38

Issue

5

Start / End Page

413 / 415

Location

England

Related Subject Headings

  • Transcription Factors
  • Gene Expression Regulation
  • Developmental Biology
  • Chromosomes
  • Chromatin
  • 42 Health sciences
  • 32 Biomedical and clinical sciences
  • 31 Biological sciences
  • 11 Medical and Health Sciences
  • 06 Biological Sciences