Viral and host factors drive a type 1 Epstein-Barr virus spontaneous lytic phenotype.
Publication
, Journal Article
Willard, KA; Barry, AP; Oduor, CI; Ong'echa, JM; Bailey, JA; Moormann, AM; Luftig, MA
Published in: mBio
December 19, 2023
Epstein-Barr virus (EBV) infects over 95% of adults worldwide. Given its connection to various cancers and autoimmune disorders, it is important to understand the mechanisms by which infection with EBV can lead to these diseases. In this study, we describe an unusual spontaneous lytic phenotype in EBV strains isolated from Kenyan endemic Burkitt lymphoma patients. Because lytic replication of EBV has been linked to the pathogenesis of various diseases, these data could illuminate viral and host factors involved in this process.
Duke Scholars
Published In
mBio
DOI
EISSN
2150-7511
Publication Date
December 19, 2023
Volume
14
Issue
6
Start / End Page
e0220423
Location
United States
Related Subject Headings
- Virus Replication
- Phenotype
- Kenya
- Humans
- Host-Pathogen Interactions
- Herpesvirus 4, Human
- Epstein-Barr Virus Infections
- Burkitt Lymphoma
- 3207 Medical microbiology
- 3107 Microbiology
Citation
APA
Chicago
ICMJE
MLA
NLM
Willard, K. A., Barry, A. P., Oduor, C. I., Ong’echa, J. M., Bailey, J. A., Moormann, A. M., & Luftig, M. A. (2023). Viral and host factors drive a type 1 Epstein-Barr virus spontaneous lytic phenotype. MBio, 14(6), e0220423. https://doi.org/10.1128/mbio.02204-23
Willard, Katherine A., Ashley P. Barry, Cliff I. Oduor, John Michael Ong’echa, Jeffrey A. Bailey, Ann M. Moormann, and Micah A. Luftig. “Viral and host factors drive a type 1 Epstein-Barr virus spontaneous lytic phenotype.” MBio 14, no. 6 (December 19, 2023): e0220423. https://doi.org/10.1128/mbio.02204-23.
Willard KA, Barry AP, Oduor CI, Ong’echa JM, Bailey JA, Moormann AM, et al. Viral and host factors drive a type 1 Epstein-Barr virus spontaneous lytic phenotype. mBio. 2023 Dec 19;14(6):e0220423.
Willard, Katherine A., et al. “Viral and host factors drive a type 1 Epstein-Barr virus spontaneous lytic phenotype.” MBio, vol. 14, no. 6, Dec. 2023, p. e0220423. Pubmed, doi:10.1128/mbio.02204-23.
Willard KA, Barry AP, Oduor CI, Ong’echa JM, Bailey JA, Moormann AM, Luftig MA. Viral and host factors drive a type 1 Epstein-Barr virus spontaneous lytic phenotype. mBio. 2023 Dec 19;14(6):e0220423.
Published In
mBio
DOI
EISSN
2150-7511
Publication Date
December 19, 2023
Volume
14
Issue
6
Start / End Page
e0220423
Location
United States
Related Subject Headings
- Virus Replication
- Phenotype
- Kenya
- Humans
- Host-Pathogen Interactions
- Herpesvirus 4, Human
- Epstein-Barr Virus Infections
- Burkitt Lymphoma
- 3207 Medical microbiology
- 3107 Microbiology