Osteoimmunology: Interactions With the Immune System in Spinal Fusion.
Publication
, Journal Article
Bergin, SM; Crutcher, CL; Keeler, C; Rocos, B; Haglund, MM; Michael Guo, H; Gottfried, ON; Richardson, WJ; Than, KD
Published in: Int J Spine Surg
December 27, 2023
Spinal fusion is important for the clinical success of patients undergoing surgery, and the immune system plays an increasingly recognized role. Osteoimmunology is the study of the interactions between the immune system and bone. Inflammation impacts the osteogenic, osteoconductive, and osteoinductive properties of bone grafts and substitutes and ultimately influences the success of spinal fusion. Macrophages have emerged as important cells for coordinating the immune response following spinal fusion surgery, and macrophage-derived cytokines impact each phase of bone graft healing. This review explores the cellular and molecular immune processes that regulate bone homeostasis and healing during spinal fusion.
Duke Scholars
Published In
Int J Spine Surg
DOI
ISSN
2211-4599
Publication Date
December 27, 2023
Volume
17
Issue
S3
Start / End Page
S9 / S17
Location
Netherlands
Related Subject Headings
- 3202 Clinical sciences
- 1109 Neurosciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Bergin, S. M., Crutcher, C. L., Keeler, C., Rocos, B., Haglund, M. M., Michael Guo, H., … Than, K. D. (2023). Osteoimmunology: Interactions With the Immune System in Spinal Fusion. Int J Spine Surg, 17(S3), S9–S17. https://doi.org/10.14444/8556
Bergin, Stephen M., Clifford L. Crutcher, Carolyn Keeler, Brett Rocos, Michael M. Haglund, H. Michael Guo, Oren N. Gottfried, William J. Richardson, and Khoi D. Than. “Osteoimmunology: Interactions With the Immune System in Spinal Fusion.” Int J Spine Surg 17, no. S3 (December 27, 2023): S9–17. https://doi.org/10.14444/8556.
Bergin SM, Crutcher CL, Keeler C, Rocos B, Haglund MM, Michael Guo H, et al. Osteoimmunology: Interactions With the Immune System in Spinal Fusion. Int J Spine Surg. 2023 Dec 27;17(S3):S9–17.
Bergin, Stephen M., et al. “Osteoimmunology: Interactions With the Immune System in Spinal Fusion.” Int J Spine Surg, vol. 17, no. S3, Dec. 2023, pp. S9–17. Pubmed, doi:10.14444/8556.
Bergin SM, Crutcher CL, Keeler C, Rocos B, Haglund MM, Michael Guo H, Gottfried ON, Richardson WJ, Than KD. Osteoimmunology: Interactions With the Immune System in Spinal Fusion. Int J Spine Surg. 2023 Dec 27;17(S3):S9–S17.
Published In
Int J Spine Surg
DOI
ISSN
2211-4599
Publication Date
December 27, 2023
Volume
17
Issue
S3
Start / End Page
S9 / S17
Location
Netherlands
Related Subject Headings
- 3202 Clinical sciences
- 1109 Neurosciences