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Does diabetes affect outcome or reoperation rate after lumbar decompression or arthrodesis? A matched analysis of the Quality Outcomes Database data set.

Publication ,  Journal Article
Mooney, J; Nathani, KR; Zeitouni, D; Michalopoulos, GD; Wang, MY; Coric, D; Chan, AK; Lu, DC; Sherrod, BA; Gottfried, ON; Shaffrey, CI ...
Published in: J Neurosurg Spine
March 1, 2024

OBJECTIVE: Diabetes mellitus (DM) is a known risk factor for postsurgical and systemic complications after lumbar spinal surgery. Smaller studies have also demonstrated diminished improvements in patient-reported outcomes (PROs), with increased reoperation and readmission rates after lumbar surgery in patients with DM. The authors aimed to examine longer-term PROs in patients with DM undergoing lumbar decompression and/or arthrodesis for degenerative pathology. METHODS: The Quality Outcomes Database was queried for patients undergoing elective lumbar decompression and/or arthrodesis for degenerative pathology. Patients were grouped into DM and non-DM groups and optimally matched in a 1:1 ratio on 31 baseline variables, including the number of operated levels. Outcomes of interest were readmissions and reoperations at 30 and 90 days after surgery in addition to improvements in Oswestry Disability Index, back pain, and leg pain scores and quality-adjusted life-years at 90 days after surgery. RESULTS: The matched decompression cohort comprised 7836 patients (3236 [41.3] females) with a mean age of 63.5 ± 12.6 years, and the matched arthrodesis cohort comprised 7336 patients (3907 [53.3%] females) with a mean age of 64.8 ± 10.3 years. In patients undergoing lumbar decompression, no significant differences in nonroutine discharge, length of stay (LOS), readmissions, reoperations, and PROs were observed. In patients undergoing lumbar arthrodesis, nonroutine discharge (15.7% vs 13.4%, p < 0.01), LOS (3.2 ± 2.0 vs 3.0 ± 3.5 days, p < 0.01), 30-day (6.5% vs 4.4%, p < 0.01) and 90-day (9.1% vs 7.0%, p < 0.01) readmission rates, and the 90-day reoperation rate (4.3% vs 3.2%, p = 0.01) were all significantly higher in the DM group. For DM patients undergoing lumbar arthrodesis, subgroup analyses demonstrated a significantly higher risk of poor surgical outcomes with the open approach. CONCLUSIONS: Patients with and without DM undergoing lumbar spinal decompression alone have comparable readmission and reoperation rates, while those undergoing arthrodesis procedures have a higher risk of poor surgical outcomes up to 90 days after surgery. Surgeons should target optimal DM control preoperatively, particularly for patients undergoing elective lumbar arthrodesis.

Duke Scholars

Published In

J Neurosurg Spine

DOI

EISSN

1547-5646

Publication Date

March 1, 2024

Volume

40

Issue

3

Start / End Page

331 / 342

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Spinal Fusion
  • Reoperation
  • Orthopedics
  • Middle Aged
  • Male
  • Humans
  • Female
  • Diabetes Mellitus
  • Decompression
 

Citation

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Mooney, J., Nathani, K. R., Zeitouni, D., Michalopoulos, G. D., Wang, M. Y., Coric, D., … Bydon, M. (2024). Does diabetes affect outcome or reoperation rate after lumbar decompression or arthrodesis? A matched analysis of the Quality Outcomes Database data set. J Neurosurg Spine, 40(3), 331–342. https://doi.org/10.3171/2023.9.SPINE23522
Mooney, James, Karim Rizwan Nathani, Daniel Zeitouni, Giorgos D. Michalopoulos, Michael Y. Wang, Domagoj Coric, Andrew K. Chan, et al. “Does diabetes affect outcome or reoperation rate after lumbar decompression or arthrodesis? A matched analysis of the Quality Outcomes Database data set.J Neurosurg Spine 40, no. 3 (March 1, 2024): 331–42. https://doi.org/10.3171/2023.9.SPINE23522.
Mooney J, Nathani KR, Zeitouni D, Michalopoulos GD, Wang MY, Coric D, et al. Does diabetes affect outcome or reoperation rate after lumbar decompression or arthrodesis? A matched analysis of the Quality Outcomes Database data set. J Neurosurg Spine. 2024 Mar 1;40(3):331–42.
Mooney, James, et al. “Does diabetes affect outcome or reoperation rate after lumbar decompression or arthrodesis? A matched analysis of the Quality Outcomes Database data set.J Neurosurg Spine, vol. 40, no. 3, Mar. 2024, pp. 331–42. Pubmed, doi:10.3171/2023.9.SPINE23522.
Mooney J, Nathani KR, Zeitouni D, Michalopoulos GD, Wang MY, Coric D, Chan AK, Lu DC, Sherrod BA, Gottfried ON, Shaffrey CI, Than KD, Goldberg JL, Hussain I, Virk MS, Agarwal N, Glassman SD, Shaffrey ME, Park P, Foley KT, Chou D, Slotkin JR, Tumialán LM, Upadhyaya CD, Potts EA, Fu K-MG, Haid RW, Knightly JJ, Mummaneni PV, Bisson EF, Asher AL, Bydon M. Does diabetes affect outcome or reoperation rate after lumbar decompression or arthrodesis? A matched analysis of the Quality Outcomes Database data set. J Neurosurg Spine. 2024 Mar 1;40(3):331–342.

Published In

J Neurosurg Spine

DOI

EISSN

1547-5646

Publication Date

March 1, 2024

Volume

40

Issue

3

Start / End Page

331 / 342

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Spinal Fusion
  • Reoperation
  • Orthopedics
  • Middle Aged
  • Male
  • Humans
  • Female
  • Diabetes Mellitus
  • Decompression