Recrudescence of Severe Carbamazepine- Induced DRESS Syndrome after Initiation of Levetiracetam.
Publication
, Journal Article
Jiang, SW; Floyd, L; Cardones, AR; Selim, MA; Shearer, SM
Published in: Skinmed
2023
Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a potentially fatal cutaneous hypersensitivity reaction commonly precipitated by antiepileptic drugs (AEDs). Cross-reactivity among aromatic AEDs is well-documented, but between aromatic and nonaromatic AEDs. We report a patient with severe DRESS syndrome precipitated by aromatic AED carbamazepine with recrudescence approximately 2 weeks after substitution with nonaromatic AED levetiracetam. The patient was treated with high-dose corticosteroids and switched to the benzodiazepine AED clobazam. At follow-up appointment several weeks later, the patient's rash, liver injury, and eosinophilia had resolved.
Duke Scholars
Published In
Skinmed
EISSN
1751-7125
Publication Date
2023
Volume
21
Issue
6
Start / End Page
445 / 447
Location
United States
Related Subject Headings
- Levetiracetam
- Humans
- Eosinophilia
- Drug Hypersensitivity Syndrome
- Dermatology & Venereal Diseases
- Carbamazepine
- Benzodiazepines
- Anticonvulsants
Citation
APA
Chicago
ICMJE
MLA
NLM
Jiang, S. W., Floyd, L., Cardones, A. R., Selim, M. A., & Shearer, S. M. (2023). Recrudescence of Severe Carbamazepine- Induced DRESS Syndrome after Initiation of Levetiracetam. Skinmed, 21(6), 445–447.
Jiang, Simon W., Lauren Floyd, Adela R. Cardones, M Angelica Selim, and Sabrina M. Shearer. “Recrudescence of Severe Carbamazepine- Induced DRESS Syndrome after Initiation of Levetiracetam.” Skinmed 21, no. 6 (2023): 445–47.
Jiang SW, Floyd L, Cardones AR, Selim MA, Shearer SM. Recrudescence of Severe Carbamazepine- Induced DRESS Syndrome after Initiation of Levetiracetam. Skinmed. 2023;21(6):445–7.
Jiang, Simon W., et al. “Recrudescence of Severe Carbamazepine- Induced DRESS Syndrome after Initiation of Levetiracetam.” Skinmed, vol. 21, no. 6, 2023, pp. 445–47.
Jiang SW, Floyd L, Cardones AR, Selim MA, Shearer SM. Recrudescence of Severe Carbamazepine- Induced DRESS Syndrome after Initiation of Levetiracetam. Skinmed. 2023;21(6):445–447.
Published In
Skinmed
EISSN
1751-7125
Publication Date
2023
Volume
21
Issue
6
Start / End Page
445 / 447
Location
United States
Related Subject Headings
- Levetiracetam
- Humans
- Eosinophilia
- Drug Hypersensitivity Syndrome
- Dermatology & Venereal Diseases
- Carbamazepine
- Benzodiazepines
- Anticonvulsants