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Isoscoparins R and S, two new ent-clerodane diterpenoids from Isodon scoparius.

Publication ,  Journal Article
Li, X-R; Fu, Q; Zhou, M; Hu, K; Du, X; Li, X-N; Sun, H-D; Yue, J-B; Zhang, H-B; Puno, P-T
Published in: Journal of Asian natural products research
October 2019

Two new ent-clerodane diterpenoids, named isoscoparins R and S (1 and 2), were isolated from the aerial parts of Isodon scoparius. Their structures were characterized mainly by analyzing the NMR and HRESIMS data, and the relative configuration of compound 1 was determined by single-crystal X-ray diffraction. Compound 2 showed weak activity as an autophagic inhibitor.

Duke Scholars

Published In

Journal of Asian natural products research

DOI

EISSN

1477-2213

ISSN

1028-6020

Publication Date

October 2019

Volume

21

Issue

10

Start / End Page

977 / 984

Related Subject Headings

  • X-Ray Diffraction
  • Spectrometry, Mass, Electrospray Ionization
  • Plant Components, Aerial
  • Molecular Structure
  • Medicinal & Biomolecular Chemistry
  • Magnetic Resonance Spectroscopy
  • Isodon
  • Immunosuppressive Agents
  • Humans
  • Hela Cells
 

Citation

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ICMJE
MLA
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Li, X.-R., Fu, Q., Zhou, M., Hu, K., Du, X., Li, X.-N., … Puno, P.-T. (2019). Isoscoparins R and S, two new ent-clerodane diterpenoids from Isodon scoparius. Journal of Asian Natural Products Research, 21(10), 977–984. https://doi.org/10.1080/10286020.2018.1481054
Li, Xing-Ren, Qiang Fu, Min Zhou, Kun Hu, Xue Du, Xiao-Nian Li, Han-Dong Sun, Jian-Bo Yue, Hong-Bin Zhang, and Pema-Tenzin Puno. “Isoscoparins R and S, two new ent-clerodane diterpenoids from Isodon scoparius.Journal of Asian Natural Products Research 21, no. 10 (October 2019): 977–84. https://doi.org/10.1080/10286020.2018.1481054.
Li X-R, Fu Q, Zhou M, Hu K, Du X, Li X-N, et al. Isoscoparins R and S, two new ent-clerodane diterpenoids from Isodon scoparius. Journal of Asian natural products research. 2019 Oct;21(10):977–84.
Li, Xing-Ren, et al. “Isoscoparins R and S, two new ent-clerodane diterpenoids from Isodon scoparius.Journal of Asian Natural Products Research, vol. 21, no. 10, Oct. 2019, pp. 977–84. Epmc, doi:10.1080/10286020.2018.1481054.
Li X-R, Fu Q, Zhou M, Hu K, Du X, Li X-N, Sun H-D, Yue J-B, Zhang H-B, Puno P-T. Isoscoparins R and S, two new ent-clerodane diterpenoids from Isodon scoparius. Journal of Asian natural products research. 2019 Oct;21(10):977–984.

Published In

Journal of Asian natural products research

DOI

EISSN

1477-2213

ISSN

1028-6020

Publication Date

October 2019

Volume

21

Issue

10

Start / End Page

977 / 984

Related Subject Headings

  • X-Ray Diffraction
  • Spectrometry, Mass, Electrospray Ionization
  • Plant Components, Aerial
  • Molecular Structure
  • Medicinal & Biomolecular Chemistry
  • Magnetic Resonance Spectroscopy
  • Isodon
  • Immunosuppressive Agents
  • Humans
  • Hela Cells