Thrombolysis for ischaemic stroke despite direct oral anticoagulation.
Publication
, Journal Article
Purrucker, JC; Meinel, TR; Wilson, D; Xian, Y; Wu, TY; Seiffge, DJ
Published in: Stroke Vasc Neurol
November 5, 2024
Intravenous thrombolysis is not recommended in anticoagulated patients receiving direct oral anticoagulants (DOACs) and a recent intake within the last 48 hours in US and European guidelines. However, three observational studies now suggest safety of thrombolysis in patients with recent intake of DOACs, and thus support previous experimental data. In this perspective, the current evidence and practical consequences are discussed.
Duke Scholars
Published In
Stroke Vasc Neurol
DOI
EISSN
2059-8696
Publication Date
November 5, 2024
Volume
9
Issue
5
Start / End Page
464 / 466
Location
England
Related Subject Headings
- Treatment Outcome
- Time Factors
- Thrombolytic Therapy
- Risk Factors
- Risk Assessment
- Ischemic Stroke
- Humans
- Hemorrhage
- Fibrinolytic Agents
- Clinical Decision-Making
Citation
APA
Chicago
ICMJE
MLA
NLM
Purrucker, J. C., Meinel, T. R., Wilson, D., Xian, Y., Wu, T. Y., & Seiffge, D. J. (2024). Thrombolysis for ischaemic stroke despite direct oral anticoagulation. Stroke Vasc Neurol, 9(5), 464–466. https://doi.org/10.1136/svn-2023-002727
Purrucker, Jan C., Thomas R. Meinel, Duncan Wilson, Ying Xian, Teddy Y. Wu, and David J. Seiffge. “Thrombolysis for ischaemic stroke despite direct oral anticoagulation.” Stroke Vasc Neurol 9, no. 5 (November 5, 2024): 464–66. https://doi.org/10.1136/svn-2023-002727.
Purrucker JC, Meinel TR, Wilson D, Xian Y, Wu TY, Seiffge DJ. Thrombolysis for ischaemic stroke despite direct oral anticoagulation. Stroke Vasc Neurol. 2024 Nov 5;9(5):464–6.
Purrucker, Jan C., et al. “Thrombolysis for ischaemic stroke despite direct oral anticoagulation.” Stroke Vasc Neurol, vol. 9, no. 5, Nov. 2024, pp. 464–66. Pubmed, doi:10.1136/svn-2023-002727.
Purrucker JC, Meinel TR, Wilson D, Xian Y, Wu TY, Seiffge DJ. Thrombolysis for ischaemic stroke despite direct oral anticoagulation. Stroke Vasc Neurol. 2024 Nov 5;9(5):464–466.
Published In
Stroke Vasc Neurol
DOI
EISSN
2059-8696
Publication Date
November 5, 2024
Volume
9
Issue
5
Start / End Page
464 / 466
Location
England
Related Subject Headings
- Treatment Outcome
- Time Factors
- Thrombolytic Therapy
- Risk Factors
- Risk Assessment
- Ischemic Stroke
- Humans
- Hemorrhage
- Fibrinolytic Agents
- Clinical Decision-Making