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Revision Strategy for Proximal Junctional Failure: Combined Effect of Proximal Extension and Focal Correction.

Publication ,  Journal Article
Lafage, R; Kim, H-J; Eastlack, RK; Daniels, AH; Diebo, BG; Mundis, G; Khalifé, M; Smith, JS; Bess, SR; Shaffrey, CI; Ames, CP; Burton, DC ...
Published in: Global Spine J
April 2025

Study designRetrospective review of a prospectively-collected multicenter database.ObjectivesThe objective of this study was to determine optimal strategies in terms of focal angular correction and length of proximal extension during revision for PJF.Methods134 patients requiring proximal extension for PJF were analyzed in this study. The correlation between amount of proximal junctional angle (PJA) reduction and recurrence of proximal junctional kyphosis (PJK) and/or PJF was investigated. Following stratification by the degree of PJK correction and the numbers of levels extended proximally, rates of radiographic PJK (PJA >28° & ΔPJA >22°), and recurrent surgery for PJF were reported.ResultsBefore revision, mean PJA was 27.6° ± 14.6°. Mean number of levels extended was 6.0 ± 3.3. Average PJA reduction was 18.8° ± 18.9°. A correlation between the degree of PJA reduction and rate of recurrent PJK was observed (r = -.222). Recurrent radiographic PJK (0%) and clinical PJF (4.5%) were rare in patients undergoing extension ≥8 levels, regardless of angular correction. Patients with small reductions (<5°) and small extensions (<4 levels) experienced moderate rates of recurrent PJK (19.1%) and PJF (9.5%). Patients with large reductions (>30°) and extensions <8 levels had the highest rate of recurrent PJK (31.8%) and PJF (16.0%).ConclusionWhile the degree of focal PJK correction must be determined by the treating surgeon based upon clinical goals, recurrent PJK may be minimized by limiting reduction to <30°. If larger PJA correction is required, more extensive proximal fusion constructs may mitigate recurrent PJK/PJF rates.

Duke Scholars

Published In

Global Spine J

DOI

ISSN

2192-5682

Publication Date

April 2025

Volume

15

Issue

3

Start / End Page

1644 / 1652

Location

England

Related Subject Headings

  • 3202 Clinical sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Lafage, R., Kim, H.-J., Eastlack, R. K., Daniels, A. H., Diebo, B. G., Mundis, G., … ISSG. (2025). Revision Strategy for Proximal Junctional Failure: Combined Effect of Proximal Extension and Focal Correction. Global Spine J, 15(3), 1644–1652. https://doi.org/10.1177/21925682241254805
Lafage, Renaud, Han-Jo Kim, Robert K. Eastlack, Alan H. Daniels, Bassel G. Diebo, Greg Mundis, Marc Khalifé, et al. “Revision Strategy for Proximal Junctional Failure: Combined Effect of Proximal Extension and Focal Correction.Global Spine J 15, no. 3 (April 2025): 1644–52. https://doi.org/10.1177/21925682241254805.
Lafage R, Kim H-J, Eastlack RK, Daniels AH, Diebo BG, Mundis G, et al. Revision Strategy for Proximal Junctional Failure: Combined Effect of Proximal Extension and Focal Correction. Global Spine J. 2025 Apr;15(3):1644–52.
Lafage, Renaud, et al. “Revision Strategy for Proximal Junctional Failure: Combined Effect of Proximal Extension and Focal Correction.Global Spine J, vol. 15, no. 3, Apr. 2025, pp. 1644–52. Pubmed, doi:10.1177/21925682241254805.
Lafage R, Kim H-J, Eastlack RK, Daniels AH, Diebo BG, Mundis G, Khalifé M, Smith JS, Bess SR, Shaffrey CI, Ames CP, Burton DC, Gupta MC, Klineberg EO, Schwab FJ, Lafage V, ISSG. Revision Strategy for Proximal Junctional Failure: Combined Effect of Proximal Extension and Focal Correction. Global Spine J. 2025 Apr;15(3):1644–1652.
Journal cover image

Published In

Global Spine J

DOI

ISSN

2192-5682

Publication Date

April 2025

Volume

15

Issue

3

Start / End Page

1644 / 1652

Location

England

Related Subject Headings

  • 3202 Clinical sciences