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Are insufficient corrections a major factor in distal junctional kyphosis? A simulated analysis of cervical deformity correction using in-construct measurements.

Publication ,  Journal Article
Ani, F; Sissman, E; Woo, D; Soroceanu, A; Mundis, G; Eastlack, RK; Smith, JS; Hamilton, DK; Kim, HJ; Daniels, AH; Klineberg, EO; Neuman, B ...
Published in: J Neurosurg Spine
May 1, 2024

OBJECTIVE: The present study utilized recently developed in-construct measurements in simulations of cervical deformity surgery in order to assess undercorrection and predict distal junctional kyphosis (DJK). METHODS: A retrospective review of a database of operative cervical deformity patients was analyzed for severe DJK and mild DJK. C2-lower instrumented vertebra (LIV) sagittal angle (SA) was measured postoperatively, and the correction was simulated in the preoperative radiograph in order to match the C2-LIV by using the planning software. Linear regression analysis that used C2 pelvic angle (CPA) and pelvic tilt (PT) determined the simulated PT that matched the virtual CPA. Linear regression analysis was used to determine the C2-T1 SA, C2-T4 SA, and C2-T10 SA that corresponded to DJK of 20° and cervical sagittal vertical axis (cSVA) of 40 mm. RESULTS: Sixty-nine cervical deformity patients were included. Severe and mild DJK occurred in 11 (16%) and 22 (32%) patients, respectively; 3 (4%) required DJK revision. Simulated corrections demonstrated that severe and mild DJK patients had worse alignment compared to non-DJK patients in terms of cSVA (42.5 mm vs 33.0 mm vs 23.4 mm, p < 0.001) and C2-LIV SVA (68.9 mm vs 57.3 mm vs 36.8 mm, p < 0.001). Linear regression revealed the relationships between in-construct measures (C2-T1 SA, C2-T4 SA, and C2-T10 SA), cSVA, and change in DJK (all R > 0.57, p < 0.001). A cSVA of 40 mm corresponded to C2-T4 SA of 10.4° and C2-T10 SA of 28.0°. A DJK angle change of 10° corresponded to C2-T4 SA of 5.8° and C2-T10 SA of 20.1°. CONCLUSIONS: Simulated cervical deformity corrections demonstrated that severe DJK patients have insufficient corrections compared to patients without DJK. In-construct measures assess sagittal alignment within the fusion separate from DJK and subjacent compensation. They can be useful as intraoperative tools to gauge the adequacy of cervical deformity correction.

Duke Scholars

Published In

J Neurosurg Spine

DOI

EISSN

1547-5646

Publication Date

May 1, 2024

Volume

40

Issue

5

Start / End Page

622 / 629

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Spinal Fusion
  • Retrospective Studies
  • Orthopedics
  • Middle Aged
  • Male
  • Kyphosis
  • Humans
  • Female
  • Cervical Vertebrae
 

Citation

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Ani, F., Sissman, E., Woo, D., Soroceanu, A., Mundis, G., Eastlack, R. K., … Protopsaltis, T. S. (2024). Are insufficient corrections a major factor in distal junctional kyphosis? A simulated analysis of cervical deformity correction using in-construct measurements. J Neurosurg Spine, 40(5), 622–629. https://doi.org/10.3171/2023.12.SPINE23481
Ani, Fares, Ethan Sissman, Dainn Woo, Alex Soroceanu, Gregory Mundis, Robert K. Eastlack, Justin S. Smith, et al. “Are insufficient corrections a major factor in distal junctional kyphosis? A simulated analysis of cervical deformity correction using in-construct measurements.J Neurosurg Spine 40, no. 5 (May 1, 2024): 622–29. https://doi.org/10.3171/2023.12.SPINE23481.
Ani F, Sissman E, Woo D, Soroceanu A, Mundis G, Eastlack RK, et al. Are insufficient corrections a major factor in distal junctional kyphosis? A simulated analysis of cervical deformity correction using in-construct measurements. J Neurosurg Spine. 2024 May 1;40(5):622–9.
Ani, Fares, et al. “Are insufficient corrections a major factor in distal junctional kyphosis? A simulated analysis of cervical deformity correction using in-construct measurements.J Neurosurg Spine, vol. 40, no. 5, May 2024, pp. 622–29. Pubmed, doi:10.3171/2023.12.SPINE23481.
Ani F, Sissman E, Woo D, Soroceanu A, Mundis G, Eastlack RK, Smith JS, Hamilton DK, Kim HJ, Daniels AH, Klineberg EO, Neuman B, Sciubba DM, Gupta MC, Kebaish KM, Passias PG, Hart RA, Bess S, Shaffrey CI, Schwab FJ, Lafage V, Ames CP, Protopsaltis TS. Are insufficient corrections a major factor in distal junctional kyphosis? A simulated analysis of cervical deformity correction using in-construct measurements. J Neurosurg Spine. 2024 May 1;40(5):622–629.

Published In

J Neurosurg Spine

DOI

EISSN

1547-5646

Publication Date

May 1, 2024

Volume

40

Issue

5

Start / End Page

622 / 629

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Spinal Fusion
  • Retrospective Studies
  • Orthopedics
  • Middle Aged
  • Male
  • Kyphosis
  • Humans
  • Female
  • Cervical Vertebrae