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Treatment of relapsed/refractory severe aplastic anemia in children: Evidence-based recommendations.

Publication ,  Journal Article
Shimano, KA; Sasa, G; Broglie, L; Gloude, NJ; Myers, K; Nakano, TA; Sharathkumar, A; Rothman, JA; Pereda, MA; Overholt, K; Narla, A; Lau, BW ...
Published in: Pediatr Blood Cancer
August 2024

Severe aplastic anemia (SAA) is a rare potentially fatal hematologic disorder. Although overall outcomes with treatment are excellent, there are variations in management approach, including differences in treatment between adult and pediatric patients. Certain aspects of treatment are under active investigation in clinical trials. Because of the rarity of the disease, some pediatric hematologists may have relatively limited experience with the complex management of SAA. The following recommendations reflect an up-to-date evidence-based approach to the treatment of children with relapsed or refractory SAA.

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Published In

Pediatr Blood Cancer

DOI

EISSN

1545-5017

Publication Date

August 2024

Volume

71

Issue

8

Start / End Page

e31075

Location

United States

Related Subject Headings

  • Recurrence
  • Oncology & Carcinogenesis
  • Humans
  • Hematopoietic Stem Cell Transplantation
  • Evidence-Based Medicine
  • Child
  • Anemia, Aplastic
  • 3213 Paediatrics
  • 3211 Oncology and carcinogenesis
  • 1114 Paediatrics and Reproductive Medicine
 

Citation

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Shimano, K. A., Sasa, G., Broglie, L., Gloude, N. J., Myers, K., Nakano, T. A., … Boklan, J. (2024). Treatment of relapsed/refractory severe aplastic anemia in children: Evidence-based recommendations. Pediatr Blood Cancer, 71(8), e31075. https://doi.org/10.1002/pbc.31075
Shimano, Kristin A., Ghadir Sasa, Larisa Broglie, Nicholas J. Gloude, Kasiani Myers, Taizo A. Nakano, Anjali Sharathkumar, et al. “Treatment of relapsed/refractory severe aplastic anemia in children: Evidence-based recommendations.Pediatr Blood Cancer 71, no. 8 (August 2024): e31075. https://doi.org/10.1002/pbc.31075.
Shimano KA, Sasa G, Broglie L, Gloude NJ, Myers K, Nakano TA, et al. Treatment of relapsed/refractory severe aplastic anemia in children: Evidence-based recommendations. Pediatr Blood Cancer. 2024 Aug;71(8):e31075.
Shimano, Kristin A., et al. “Treatment of relapsed/refractory severe aplastic anemia in children: Evidence-based recommendations.Pediatr Blood Cancer, vol. 71, no. 8, Aug. 2024, p. e31075. Pubmed, doi:10.1002/pbc.31075.
Shimano KA, Sasa G, Broglie L, Gloude NJ, Myers K, Nakano TA, Sharathkumar A, Rothman JA, Pereda MA, Overholt K, Narla A, McGuinn C, Lau BW, Geddis AE, Dror Y, de Jong JLO, Castillo P, Allen SW, Boklan J. Treatment of relapsed/refractory severe aplastic anemia in children: Evidence-based recommendations. Pediatr Blood Cancer. 2024 Aug;71(8):e31075.
Journal cover image

Published In

Pediatr Blood Cancer

DOI

EISSN

1545-5017

Publication Date

August 2024

Volume

71

Issue

8

Start / End Page

e31075

Location

United States

Related Subject Headings

  • Recurrence
  • Oncology & Carcinogenesis
  • Humans
  • Hematopoietic Stem Cell Transplantation
  • Evidence-Based Medicine
  • Child
  • Anemia, Aplastic
  • 3213 Paediatrics
  • 3211 Oncology and carcinogenesis
  • 1114 Paediatrics and Reproductive Medicine