Scholars@Duke publication: The dynamic changes of DNA methylation in primordial germ cell differentiation.

The dynamic changes of DNA methylation in primordial germ cell differentiation.

Publication , Journal Article

Duan, L; Liu, Y; Wang, J; Liao, J; Hu, J

Published in: Gene

October 15, 2016

The discovery of DNA methylation has provided a new perspective on how DNA may be dynamically regulated in the mammalian genome. DNA methylation is a dynamic process with a demethylation and de novo methylation from primordial germ cell to differentiation. DNA methylation and demethylation have been proposed to play important roles in somatic cell reprogramming. Some essential components were discussed, such as hydroxymethylation which has recently been confirmed as a modification of developmental importance.

Duke Scholars

Author Yongmei Liu Medicine, Cardiology

Published In

Gene

DOI

10.1016/j.gene.2016.06.036

EISSN

1879-0038

Publication Date

October 15, 2016

Volume

591

Issue

Start / End Page

305 / 312

Location

Netherlands

Related Subject Headings

Humans
Germ Cells
Gametogenesis
Developmental Biology
DNA Methylation
Animals
3105 Genetics
3102 Bioinformatics and computational biology
3101 Biochemistry and cell biology
1108 Medical Microbiology

Citation

APA

Chicago

ICMJE

MLA

NLM

Duan, L., Liu, Y., Wang, J., Liao, J., & Hu, J. (2016). The dynamic changes of DNA methylation in primordial germ cell differentiation. Gene, 591(2), 305–312. https://doi.org/10.1016/j.gene.2016.06.036

Duan, Lian, Yongmei Liu, Jie Wang, Jiangquan Liao, and Junyuan Hu. “The dynamic changes of DNA methylation in primordial germ cell differentiation.” Gene 591, no. 2 (October 15, 2016): 305–12. https://doi.org/10.1016/j.gene.2016.06.036.

Duan L, Liu Y, Wang J, Liao J, Hu J. The dynamic changes of DNA methylation in primordial germ cell differentiation. Gene. 2016 Oct 15;591(2):305–12.

Duan, Lian, et al. “The dynamic changes of DNA methylation in primordial germ cell differentiation.” Gene, vol. 591, no. 2, Oct. 2016, pp. 305–12. Pubmed, doi:10.1016/j.gene.2016.06.036.

Duan L, Liu Y, Wang J, Liao J, Hu J. The dynamic changes of DNA methylation in primordial germ cell differentiation. Gene. 2016 Oct 15;591(2):305–312.