X-ray diffraction imaging of glioblastoma and ductal carcinoma in-situ
Publication
, Conference
Greenberg, JA; Richmond, T; Gude, ZW; Li, X; Nanda, A; Coccarelli, D; Factor, R; McCall, S; Kapadia, A
Published in: Progress in Biomedical Optics and Imaging Proceedings of SPIE
January 1, 2024
Specimen radiography is critical to cancer diagnostics, but conventional transmission X-ray imaging often lacks the contrast to conclusively differentiate healthy from cancerous tissue. X-ray diffraction (XRD), however, has been shown to be sensitive to structural changes in tissue that are correlated with cancer progression. We use a home-built XRD imaging system to study glioblastoma in brain tissue and ductal carcinoma in situ (DCIS) in breast tissue, and identify both commonalities and unique aspects of cancer structural changes in the brain and breast. These findings demonstrate the potential for XRD imaging as a new tool for use in both research and diagnostic medicine.
Duke Scholars
Published In
Progress in Biomedical Optics and Imaging Proceedings of SPIE
DOI
ISSN
1605-7422
Publication Date
January 1, 2024
Volume
12925
Citation
APA
Chicago
ICMJE
MLA
NLM
Greenberg, J. A., Richmond, T., Gude, Z. W., Li, X., Nanda, A., Coccarelli, D., … Kapadia, A. (2024). X-ray diffraction imaging of glioblastoma and ductal carcinoma in-situ. In Progress in Biomedical Optics and Imaging Proceedings of SPIE (Vol. 12925). https://doi.org/10.1117/12.3006600
Greenberg, J. A., T. Richmond, Z. W. Gude, X. Li, A. Nanda, D. Coccarelli, R. Factor, S. McCall, and A. Kapadia. “X-ray diffraction imaging of glioblastoma and ductal carcinoma in-situ.” In Progress in Biomedical Optics and Imaging Proceedings of SPIE, Vol. 12925, 2024. https://doi.org/10.1117/12.3006600.
Greenberg JA, Richmond T, Gude ZW, Li X, Nanda A, Coccarelli D, et al. X-ray diffraction imaging of glioblastoma and ductal carcinoma in-situ. In: Progress in Biomedical Optics and Imaging Proceedings of SPIE. 2024.
Greenberg, J. A., et al. “X-ray diffraction imaging of glioblastoma and ductal carcinoma in-situ.” Progress in Biomedical Optics and Imaging Proceedings of SPIE, vol. 12925, 2024. Scopus, doi:10.1117/12.3006600.
Greenberg JA, Richmond T, Gude ZW, Li X, Nanda A, Coccarelli D, Factor R, McCall S, Kapadia A. X-ray diffraction imaging of glioblastoma and ductal carcinoma in-situ. Progress in Biomedical Optics and Imaging Proceedings of SPIE. 2024.
Published In
Progress in Biomedical Optics and Imaging Proceedings of SPIE
DOI
ISSN
1605-7422
Publication Date
January 1, 2024
Volume
12925