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Ongoing and future clinical trials of device therapies for patients with heart failure.

Publication ,  Journal Article
Khalid, SN; Mansoor, T; Bilal, MI; Ijaz, SH; Fudim, M; Greene, SJ; Nambi, V; Virani, SS; Fonarow, GC; Abramov, D; Minhas, AMK
Published in: Curr Probl Cardiol
November 2024

Heart failure continues to pose a significant burden in terms of morbidity, mortality, and healthcare costs worldwide despite the implementation of guideline-directed medical therapy. Addressing this challenge and improving clinical outcomes for this patient population remains an urgent priority. Recognizing the limitations in current medical approaches and exploring strategies to overcome these limitations are crucial steps toward improving future outcomes. Various device-based interventions, such as Cardiac Resynchronization Therapy devices and Left Ventricular Assist Devices, have demonstrated notable benefits for individuals with heart failure. Our review is aimed at summarizing the ongoing research into new device therapies for heart failure, emphasizing their potential to overcome the current challenges in treatment. By utilizing Clinicaltrials.gov, an online repository, we conducted a comprehensive search for trials investigating emerging device therapies for patients dealing with heart failure.

Duke Scholars

Published In

Curr Probl Cardiol

DOI

EISSN

1535-6280

Publication Date

November 2024

Volume

49

Issue

11

Start / End Page

102805

Location

Netherlands

Related Subject Headings

  • Humans
  • Heart-Assist Devices
  • Heart Failure
  • Defibrillators, Implantable
  • Clinical Trials as Topic
  • Cardiovascular System & Hematology
  • Cardiac Resynchronization Therapy Devices
  • Cardiac Resynchronization Therapy
  • 3201 Cardiovascular medicine and haematology
  • 1102 Cardiorespiratory Medicine and Haematology
 

Citation

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Khalid, S. N., Mansoor, T., Bilal, M. I., Ijaz, S. H., Fudim, M., Greene, S. J., … Minhas, A. M. K. (2024). Ongoing and future clinical trials of device therapies for patients with heart failure. Curr Probl Cardiol, 49(11), 102805. https://doi.org/10.1016/j.cpcardiol.2024.102805
Khalid, Subaina Naeem, Taha Mansoor, Muhammad Ibraiz Bilal, Sardar Hassan Ijaz, Marat Fudim, Stephen J. Greene, Vijay Nambi, et al. “Ongoing and future clinical trials of device therapies for patients with heart failure.Curr Probl Cardiol 49, no. 11 (November 2024): 102805. https://doi.org/10.1016/j.cpcardiol.2024.102805.
Khalid SN, Mansoor T, Bilal MI, Ijaz SH, Fudim M, Greene SJ, et al. Ongoing and future clinical trials of device therapies for patients with heart failure. Curr Probl Cardiol. 2024 Nov;49(11):102805.
Khalid, Subaina Naeem, et al. “Ongoing and future clinical trials of device therapies for patients with heart failure.Curr Probl Cardiol, vol. 49, no. 11, Nov. 2024, p. 102805. Pubmed, doi:10.1016/j.cpcardiol.2024.102805.
Khalid SN, Mansoor T, Bilal MI, Ijaz SH, Fudim M, Greene SJ, Nambi V, Virani SS, Fonarow GC, Abramov D, Minhas AMK. Ongoing and future clinical trials of device therapies for patients with heart failure. Curr Probl Cardiol. 2024 Nov;49(11):102805.
Journal cover image

Published In

Curr Probl Cardiol

DOI

EISSN

1535-6280

Publication Date

November 2024

Volume

49

Issue

11

Start / End Page

102805

Location

Netherlands

Related Subject Headings

  • Humans
  • Heart-Assist Devices
  • Heart Failure
  • Defibrillators, Implantable
  • Clinical Trials as Topic
  • Cardiovascular System & Hematology
  • Cardiac Resynchronization Therapy Devices
  • Cardiac Resynchronization Therapy
  • 3201 Cardiovascular medicine and haematology
  • 1102 Cardiorespiratory Medicine and Haematology