Optimal Dynamic Treatment Regimes

A dynamic treatment regime is a set of sequential decision rules, each corresponding to a key decision point in a disease or disorder process that dictates the next treatment for a patient based on accrued information on the patient. An optimal dynamic treatment regime is a regime that leads to the most favorable outcome on average if used to select treatment for the entire patient population. This entry reviews a statistical framework in which an optimal dynamic treatment regime can be defined precisely and methods by which it can be estimated from data under appropriate assumptions.

Duke Scholars

Author Marie Davidian Biostatistics & Bioinformatics, Division of Biostatistics