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So Close yet So Far: The impact of undercorrection of cervical sagittal alignment during adult cervical deformity surgery - An Incremental correction analysis.

Publication ,  Journal Article
Das, A; Yung, A; Onafowokan, O; Mir, J; Fisher, MR; Williamson, TK; Cottrill, EJ; Buser, Z; Tretiakov, PS; Than, KD; Shah, NV; Shaffrey, CI ...
Published in: J Clin Neurosci
October 23, 2024

BACKGROUND: To compare degrees of cSVA correction and to theorize possible minimum and maximum thresholds of cSVA correction for patients to benefit clinically. METHODS: 657 operative ACD patients in a retrospective cohort study of a prospectively enrolled database with complete baseline and two year radiographic and HRQL data were examined. Patients were grouped into an optimally corrected cohort (OC; postop cSVA ≤ 4 cm) and an undercorrected cohort (UC; postop cSVA > 4 cm) based on postoperative radiographs. RESULTS: 265 patients met inclusion criteria (mean age 58.2 ± 11.4 years, BMI 28.9 ± 7.5, CCI 0.9 ± 1.3). 11.2 % of patients were UC, while 88.8 % of patients were OC. UC cohort experienced a significantly greater occurrence of radiographic complications (47.8 % v. 27.6 %, p = 0.046). UC also demonstrated a significantly greater rate of severe 6 M DJK (p < 0.001) and 1Y DJK (26.1 % v. 2.7 %, p < 0.001). In terms of HRQLs, the OC cohort demonstrated significantly greater 2Y EQ5D-Health values (76.9 v. 46.7, p = 0.012). Being UC was a significant predictor of moderate-high 1Y mJOA score (OR 3.0, CI 95 % 1.2-7.3, p = 0.015) Still, in terms of CIT, the threshold for DJF risk increased significantly (p = 0.026) when the cSVA were surgically corrected greater than 5 cm. CONCLUSION: Undercorrection of cSVA yielded worse clinical outcomes and posed a significant risk for radiographic complications. Although undercorrection does not seem to be efficacious, surgical correction beyond certain thresholds should still be respected as there is a risk for DJK on either end of the spectrum.

Duke Scholars

Published In

J Clin Neurosci

DOI

EISSN

1532-2653

Publication Date

October 23, 2024

Volume

130

Start / End Page

110869

Location

Scotland

Related Subject Headings

  • Neurology & Neurosurgery
  • 5202 Biological psychology
  • 3209 Neurosciences
  • 3202 Clinical sciences
  • 1109 Neurosciences
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
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Das, A., Yung, A., Onafowokan, O., Mir, J., Fisher, M. R., Williamson, T. K., … Passias, P. G. (2024). So Close yet So Far: The impact of undercorrection of cervical sagittal alignment during adult cervical deformity surgery - An Incremental correction analysis. J Clin Neurosci, 130, 110869. https://doi.org/10.1016/j.jocn.2024.110869
Das, Ankita, Anthony Yung, Oluwatobi Onafowokan, Jamshaid Mir, Max R. Fisher, Tyler K. Williamson, Ethan J. Cottrill, et al. “So Close yet So Far: The impact of undercorrection of cervical sagittal alignment during adult cervical deformity surgery - An Incremental correction analysis.J Clin Neurosci 130 (October 23, 2024): 110869. https://doi.org/10.1016/j.jocn.2024.110869.
Das A, Yung A, Onafowokan O, Mir J, Fisher MR, Williamson TK, et al. So Close yet So Far: The impact of undercorrection of cervical sagittal alignment during adult cervical deformity surgery - An Incremental correction analysis. J Clin Neurosci. 2024 Oct 23;130:110869.
Das, Ankita, et al. “So Close yet So Far: The impact of undercorrection of cervical sagittal alignment during adult cervical deformity surgery - An Incremental correction analysis.J Clin Neurosci, vol. 130, Oct. 2024, p. 110869. Pubmed, doi:10.1016/j.jocn.2024.110869.
Das A, Yung A, Onafowokan O, Mir J, Fisher MR, Williamson TK, Cottrill EJ, Buser Z, Tretiakov PS, Than KD, Shah NV, Shaffrey CI, Passias PG. So Close yet So Far: The impact of undercorrection of cervical sagittal alignment during adult cervical deformity surgery - An Incremental correction analysis. J Clin Neurosci. 2024 Oct 23;130:110869.
Journal cover image

Published In

J Clin Neurosci

DOI

EISSN

1532-2653

Publication Date

October 23, 2024

Volume

130

Start / End Page

110869

Location

Scotland

Related Subject Headings

  • Neurology & Neurosurgery
  • 5202 Biological psychology
  • 3209 Neurosciences
  • 3202 Clinical sciences
  • 1109 Neurosciences
  • 1103 Clinical Sciences