Expression of Concern: Increasing cardiac contractility after myocardial infarction exacerbates cardiac injury and pump dysfunction (Circulation Research (2010) 107 (800-809) DOI: 10.1161/CIRCRESAHA.110.219220)

Harvard Medical School and Brigham and Women's Hospital (BWH) have notified the American Heart Association that they have completed a review into concerns about the integrity of certain data generated in a former laboratory at BWH. The review concluded that there were issues with data reported in the following publications: 1. Circ Res. 2008;102:597-606 2. Circ Res. 2009;105:1128-1140 3. Circ Res. 2010;107:305-315 4. Circ Res. 2010;107:800-809 5. Circ Res. 2010;107:1374-1386 6. Circ Res. 2011;108:1071-1083 7. Circ Res. 2011;108:1467-1481 8. Circ Res. 2011;109:941-961 9. Circ Res. 2012;111:152-155 10. Circ Res. 2012;110:701-715 11. Circ Res. 2012;111:894-906 12. Circ Res. 2012;111:1286-1296 13. Circulation. 2011;123:1287-1296 14. Circulation. 2013;128:2211-2223 15. Circulation. 2014;129:157-172 We are communicating with the authors of these publications as well as Harvard Medical School. We are publishing this Expression of Concern while we await the outcome of these communications and to indicate that the data in the listed publications may not be reliable. N.A. Mark Estes III, MD Chairperson, AHA Scientific Publishing Committee This Expression of Concern is copublished in Circulation and Circulation Research.

Duke Scholars

Author Walter J. Koch Surgery, Cardiovascular and Thoracic Surgery