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A novel and efficient model of coronary artery ligation in the mouse.

Publication ,  Chapter
Gao, E; Koch, WJ
2013

Coronary artery ligation to induce myocardial infarction (MI) and ischemia/reperfusion (I/R) injury in mice is typically performed by an invasive and time-consuming approach that requires ventilation and a full thoracotomy (classical method), often resulting in extensive tissue damage and high mortality. Here, we describe a novel and rapid surgical method to induce MI that does not require ventilation. This method is much more efficient and safer than the classical method of MI and I/R injury.

Duke Scholars

DOI

Publication Date

2013

Volume

1037

Start / End Page

299 / 311

Related Subject Headings

  • Vascular Surgical Procedures
  • Myocardial Reperfusion Injury
  • Myocardial Infarction
  • Mice
  • Ligation
  • Disease Models, Animal
  • Developmental Biology
  • Coronary Vessels
  • Animals
  • 3404 Medicinal and biomolecular chemistry
 

Citation

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Gao, E., & Koch, W. J. (2013). A novel and efficient model of coronary artery ligation in the mouse. (Vol. 1037, pp. 299–311). https://doi.org/10.1007/978-1-62703-505-7_17
Gao, Erhe, and Walter J. Koch. “A novel and efficient model of coronary artery ligation in the mouse.,” 1037:299–311, 2013. https://doi.org/10.1007/978-1-62703-505-7_17.
Gao, Erhe, and Walter J. Koch. A novel and efficient model of coronary artery ligation in the mouse. Vol. 1037, 2013, pp. 299–311. Pubmed, doi:10.1007/978-1-62703-505-7_17.

DOI

Publication Date

2013

Volume

1037

Start / End Page

299 / 311

Related Subject Headings

  • Vascular Surgical Procedures
  • Myocardial Reperfusion Injury
  • Myocardial Infarction
  • Mice
  • Ligation
  • Disease Models, Animal
  • Developmental Biology
  • Coronary Vessels
  • Animals
  • 3404 Medicinal and biomolecular chemistry