Skip to main content
Journal cover image

Characterization of cDNA clones encoding two putative isoforms of the alpha 1 subunit of the dihydropyridine-sensitive voltage-dependent calcium channel isolated from rat brain and rat aorta.

Publication ,  Journal Article
Koch, WJ; Hui, A; Shull, GE; Ellinor, P; Schwartz, A
Published in: FEBS Lett
July 3, 1989

cDNA clones encoding rat brain and rat aorta isoforms of the alpha 1 subunit of the dihydropyridine-sensitive, voltage-dependent calcium channel were isolated and sequenced. These tissue-specific cDNA clones share significant amino acid similarity with the rabbit skeletal muscle calcium channel alpha 1 subunit (75% and 66% amino acid identity for rat brain and rat aorta isoforms, respectively). Northern analysis revealed transcript sizes of 6.5 and 8.6 kb in aorta and 8.6 kb in brain.

Duke Scholars

Published In

FEBS Lett

DOI

ISSN

0014-5793

Publication Date

July 3, 1989

Volume

250

Issue

2

Start / End Page

386 / 388

Location

England

Related Subject Headings

  • Rats
  • Molecular Sequence Data
  • Dihydropyridines
  • DNA
  • Cloning, Molecular
  • Calcium Channels
  • Calcium Channel Blockers
  • Brain
  • Blotting, Northern
  • Biochemistry & Molecular Biology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Koch, W. J., Hui, A., Shull, G. E., Ellinor, P., & Schwartz, A. (1989). Characterization of cDNA clones encoding two putative isoforms of the alpha 1 subunit of the dihydropyridine-sensitive voltage-dependent calcium channel isolated from rat brain and rat aorta. FEBS Lett, 250(2), 386–388. https://doi.org/10.1016/0014-5793(89)80761-6
Koch, W. J., A. Hui, G. E. Shull, P. Ellinor, and A. Schwartz. “Characterization of cDNA clones encoding two putative isoforms of the alpha 1 subunit of the dihydropyridine-sensitive voltage-dependent calcium channel isolated from rat brain and rat aorta.FEBS Lett 250, no. 2 (July 3, 1989): 386–88. https://doi.org/10.1016/0014-5793(89)80761-6.
Journal cover image

Published In

FEBS Lett

DOI

ISSN

0014-5793

Publication Date

July 3, 1989

Volume

250

Issue

2

Start / End Page

386 / 388

Location

England

Related Subject Headings

  • Rats
  • Molecular Sequence Data
  • Dihydropyridines
  • DNA
  • Cloning, Molecular
  • Calcium Channels
  • Calcium Channel Blockers
  • Brain
  • Blotting, Northern
  • Biochemistry & Molecular Biology