Scholars@Duke publication: Pearls and Oy-sters: A Patient on Lecanemab Newly Diagnosed With Atrial Fibrillation.

Pearls and Oy-sters: A Patient on Lecanemab Newly Diagnosed With Atrial Fibrillation.

Publication , Journal Article

Ryan, D; Zwischenberger, BA; Liu, AJ

Published in: Neurology

December 24, 2024

A 77-year-old woman with a medical history of amnestic mild cognitive impairment on lecanemab presented to the hospital with new onset shortness of breath. ECG revealed new diagnosis of atrial fibrillation with rapid ventricular response. Considering the patient's risk factors with a CHA2DS2-VASc score of 6, the patient would warrant use of anticoagulation, with the caveat that this is currently not recommended with use of lecanemab. In this case, we describe the management dilemma posed by new diagnosis of atrial fibrillation using anti-amyloid immunotherapies and suggest possible solutions in this unique population.

Duke Scholars

Author Brittany Anne Zwischenberger Surgery, Cardiovascular and Thoracic Surgery

Author Andrew John Liu Neurology, Behavioral Neurology

Author Dylan Thomas Ryan Neurology, Stroke and Vascular Neurology

Published In

Neurology

DOI

10.1212/WNL.0000000000210125

EISSN

1526-632X

Publication Date

December 24, 2024

Volume

103

Issue

Start / End Page

e210125

Location

United States

Related Subject Headings

Neurology & Neurosurgery
Humans
Female
Electrocardiography
Cognitive Dysfunction
Atrial Fibrillation
Aged
3209 Neurosciences
3202 Clinical sciences
1702 Cognitive Sciences

Citation

APA

Chicago

ICMJE

MLA

NLM

Ryan, D., Zwischenberger, B. A., & Liu, A. J. (2024). Pearls and Oy-sters: A Patient on Lecanemab Newly Diagnosed With Atrial Fibrillation. Neurology, 103(12), e210125. https://doi.org/10.1212/WNL.0000000000210125

Ryan, Dylan, Brittany A. Zwischenberger, and Andy J. Liu. “Pearls and Oy-sters: A Patient on Lecanemab Newly Diagnosed With Atrial Fibrillation.” Neurology 103, no. 12 (December 24, 2024): e210125. https://doi.org/10.1212/WNL.0000000000210125.

Ryan D, Zwischenberger BA, Liu AJ. Pearls and Oy-sters: A Patient on Lecanemab Newly Diagnosed With Atrial Fibrillation. Neurology. 2024 Dec 24;103(12):e210125.

Ryan, Dylan, et al. “Pearls and Oy-sters: A Patient on Lecanemab Newly Diagnosed With Atrial Fibrillation.” Neurology, vol. 103, no. 12, Dec. 2024, p. e210125. Pubmed, doi:10.1212/WNL.0000000000210125.

Ryan D, Zwischenberger BA, Liu AJ. Pearls and Oy-sters: A Patient on Lecanemab Newly Diagnosed With Atrial Fibrillation. Neurology. 2024 Dec 24;103(12):e210125.