Overview
While striving to provide excellent clinical care, I also have several research interests:
1. Investigate a neurodevelopmental disorder, Tuberous Sclerosis Complex, which has the potential to provide insight into the pathophysiological mechanism of a neurodegenerative disorders, Alzheimer's Disease.
2. In collaboration with Dr. Cathrine Hoyo, we are investigating an epigenetic mechanism to explain the racial disparities in the development of Alzheimer's disease between underrepresented minorities and European Americans.
3. I am interested establishing biomarkers to diagnose various neurodegenerative diseases.
1. Investigate a neurodevelopmental disorder, Tuberous Sclerosis Complex, which has the potential to provide insight into the pathophysiological mechanism of a neurodegenerative disorders, Alzheimer's Disease.
2. In collaboration with Dr. Cathrine Hoyo, we are investigating an epigenetic mechanism to explain the racial disparities in the development of Alzheimer's disease between underrepresented minorities and European Americans.
3. I am interested establishing biomarkers to diagnose various neurodegenerative diseases.
Current Appointments & Affiliations
Associate Professor of Neurology
·
2024 - Present
Neurology, Behavioral Neurology,
Neurology
Associate Professor in Pathology
·
2024 - Present
Pathology,
Clinical Science Departments
Recent Publications
DNA methylation of imprint control regions associated with Alzheimer's disease in non-Hispanic Blacks and non-Hispanic Whites.
Journal Article Clin Epigenetics · April 25, 2024 Alzheimer's disease (AD) prevalence is twice as high in non-Hispanic Blacks (NHBs) as in non-Hispanic Whites (NHWs). The objective of this study was to determine whether aberrant methylation at imprint control regions (ICRs) is associated with AD. Differen ... Full text Link to item CiteSkin Biopsy Detection of Phosphorylated α-Synuclein in Patients With Synucleinopathies.
Journal Article JAMA · April 16, 2024 IMPORTANCE: Finding a reliable diagnostic biomarker for the disorders collectively known as synucleinopathies (Parkinson disease [PD], dementia with Lewy bodies [DLB], multiple system atrophy [MSA], and pure autonomic failure [PAF]) is an urgent unmet need ... Full text Link to item CiteAssociation between F2-isoprostanes and self-reported stressors in pregnant americans of African and European ancestry.
Journal Article Heliyon · February 15, 2024 BACKGROUND: Poor birth outcomes such as preterm birth/delivery disproportionately affect African Americans compared to White individuals. Reasons for this disparity are likely multifactorial, and include prenatal psychosocial stressors, and attendant incre ... Full text Link to item CiteRecent Grants
Automated High-purity Exosome isolation-based AD diagnostics system (AHEADx)
ResearchCo-Principal Investigator · Awarded by National Institute on Aging · 2023 - 2028A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Safety, and Tolerability of BIIB080 in Subjects with Mild Cognitive Impairment Due to Alzheimer¿s Disease o
Clinical TrialPrincipal Investigator · Awarded by Biogen MA, Inc. · 2023 - 2027Adaptive Neuromodulation of Working Memory Networks in Aging and Dementia
ResearchCo Investigator · Awarded by National Institute on Aging · 2022 - 2027View All Grants
Education, Training & Certifications
Rosalind Franklin University of Medicine and Science, Chicago Medical School ·
2013
M.D.
Rosalind Franklin University of Medicine and Science ·
2008
M.S.