Recent Insights into the Evolving Role of the Gut Microbiome in Critical Care.
Publication
, Journal Article
Lee, S; Wischmeyer, PE; Mintz, CD; Serbanescu, MA
Published in: Crit Care Clin
April 2025
This review explores the evolving understanding of gut microbiota's role in critical illness, focusing on how acute illness and exposures in intensive care unit (ICU) environment negatively impact the gut microbiota and the implications of these changes on host responses in critically-ill patients. Focusing on recent findings from clinical and preclinical studies, we discuss the effects of inflammation, enteral nutrient deprivation, and antibiotics on gut microbial dynamics. This review aims to enhance comprehension of microbial dynamics in the ICU and their implications for clinical outcomes and therapeutic strategies.
Duke Scholars
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Published In
Crit Care Clin
DOI
EISSN
1557-8232
Publication Date
April 2025
Volume
41
Issue
2
Start / End Page
379 / 396
Location
United States
Related Subject Headings
- Intensive Care Units
- Humans
- Gastrointestinal Microbiome
- Emergency & Critical Care Medicine
- Critical Illness
- Critical Care
- Anti-Bacterial Agents
- 4205 Nursing
- 3202 Clinical sciences
- 1110 Nursing
Citation
APA
Chicago
ICMJE
MLA
NLM
Lee, S., Wischmeyer, P. E., Mintz, C. D., & Serbanescu, M. A. (2025). Recent Insights into the Evolving Role of the Gut Microbiome in Critical Care. Crit Care Clin, 41(2), 379–396. https://doi.org/10.1016/j.ccc.2024.11.002
Lee, Seoho, Paul E. Wischmeyer, Cyrus D. Mintz, and Mara A. Serbanescu. “Recent Insights into the Evolving Role of the Gut Microbiome in Critical Care.” Crit Care Clin 41, no. 2 (April 2025): 379–96. https://doi.org/10.1016/j.ccc.2024.11.002.
Lee S, Wischmeyer PE, Mintz CD, Serbanescu MA. Recent Insights into the Evolving Role of the Gut Microbiome in Critical Care. Crit Care Clin. 2025 Apr;41(2):379–96.
Lee, Seoho, et al. “Recent Insights into the Evolving Role of the Gut Microbiome in Critical Care.” Crit Care Clin, vol. 41, no. 2, Apr. 2025, pp. 379–96. Pubmed, doi:10.1016/j.ccc.2024.11.002.
Lee S, Wischmeyer PE, Mintz CD, Serbanescu MA. Recent Insights into the Evolving Role of the Gut Microbiome in Critical Care. Crit Care Clin. 2025 Apr;41(2):379–396.
Published In
Crit Care Clin
DOI
EISSN
1557-8232
Publication Date
April 2025
Volume
41
Issue
2
Start / End Page
379 / 396
Location
United States
Related Subject Headings
- Intensive Care Units
- Humans
- Gastrointestinal Microbiome
- Emergency & Critical Care Medicine
- Critical Illness
- Critical Care
- Anti-Bacterial Agents
- 4205 Nursing
- 3202 Clinical sciences
- 1110 Nursing