Paul Edmund Wischmeyer
Professor of Anesthesiology
Paul Wischmeyer M.D., EDIC, FASPEN, FCCM is a critical care, perioperative, and nutrition physician-researcher who specializes in enhancing preparation and recovery from surgery, critical care and COVID-19. He serves as a Tenured Professor of Anesthesiology and Surgery at Duke. He also serves as the Associate Vice Chair for Clinical Research in the Dept. of Anesthesiology and Director of the TPN/Nutrition Team at Duke. Dr. Wischmeyer earned his medical degree with honors at The University of Chicago Pritzker School of Medicine, where he was elected into the honor society of Alpha Omega Alpha for outstanding academic achievement. He completed his pediatric internship at University of Colorado Children’s Hospital and his anesthesiology/critical care residency training at the University of Chicago. He also completed a Clinical Pharmacology fellowship and the NIH K30 Clinical Research Scientist Training Program while at University of Chicago.
Dr. Wischmeyer’s clinical and research focus is in critical care, perioperative care exercise, and nutrition to help patients prepare and recover from illness and surgery. His research interests include surgical and ICU nutrition and exercise rehabilitation; role of parenteral, enteral, and oral nutrition to improve patient outcomes; perioperative optimization; post-illness muscle mass and functional recovery; and probiotics/microbiome. His research interests have also recently been focused on COVID-19 research into COVID-19 metabolism, role of probiotics in COVID19 prevention and treatment, and exercise and nutrition programs to recover from COVID-19 and Long COVID-19. Dr. Wischmeyer’s research group has been awarded multiple NIH, DOD, and other peer reviewed grants to perform research ranging from basic mechanistic cell work to large-scale multi-center clinical trials in the fields of critical care, perioperative medicine, nutrition, illness metabolism, microbiome/probiotics, and exercise interventions to improve functional outcomes. For his research work and clinical work, Dr. Wischmeyer has received numerous awards from national and international societies including, The Jeffrey Silverstein Award and Memorial Lecture for Humanism in Medicine from the American Delirium Society, The John M. Kinney Award for the most significant contribution to field of general nutrition, the Stanley Dudrick Research Scholar Award by the American Society for Parenteral and Enteral Nutrition and The Lifetime Achievement Award of the International Parenteral Nutrition Society (IPENEMA) for significant contributions to the field of nutrition. Dr. Wischmeyer has over 200 peer-reviewed publications in critical care, anesthesiology, and nutrition, including in the New England Journal of Medicine. Finally, he has been an invited speaker at numerous national and international medical meetings delivering over 850 invited presentations over his career. He has an H-index of 68 with over 15,300 citations to his work, including 50 publications with > 100 citations.
Dr. Wischmeyer passion for helping patients recover from illness and surgery arises from his personal experiences as both doctor and patient in the ICU. Dr. Wischmeyer has undergone over 20 major surgeries and personally experienced multiple ICU stays due to a childhood GI illness that took more than half of his intestinal tract. Thus, preparation for surgery/critical care and recovery from illness are a way of life for Dr. Wischmeyer that he is passionate about teaching his patients and other caregivers worldwide.
Current Research Interests
His research interests include:
1) ICU and surgical nutrition therapy
2) Personalized Exercise Interventions to promote recovery for COVID-19, Long COVID, Critical Care, and Perioperative Care
3) Health Outcome and Large Database research focused on TPN, oral/enteral nutrition, and ICU/surgical outcomes
5) Role of parenteral nutrition in improving outcomes in surgery, trauma, and critical care
6) Perioperative optimization studies
7) Post-illness muscle mass and functional recovery studies
8) Role of probiotics/microbiome in prevention of COVID-19, treating illness and improving cognition.
9) Health Outcome and Large Database research focused on TPN, oral/enteral nutrition, and ICU/surgical outcomes
10) Role of parenteral nutrition in improving outcomes in surgery, trauma, and critical care
Further, we focus on studies of metabolism, indirect calorimetry, novel muscle mass measures via ultrasound and other techniques, and body composition in illnesses including COVID-19, critical care and surgery. Finally, we carry out a range of exercise based and High Intensity Interval training interventions to improve recovery from illness (including COVID-19), from ICU and surgery.
Current Appointments & Affiliations
- Professor of Anesthesiology, Anesthesiology, Critical Care Medicine, Anesthesiology 2017
- Professor in the Department of Surgery, Trauma, Acute, and Critical Care Surgery, Surgery 2017
Contact Information
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paul.wischmeyer@duke.edu
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Paul Wischmeyer's Google Scholar Link and H-Index
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Paul Wischmeyer's Instagram Link
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Paul Wischmeyer's Lectures on YouTube Channel
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Paul Wischmeyer's LinkedIn Site
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Paul Wischmeyer's Researchgate Site
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Paul Wischmeyer's Twitter Site
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Perioperative and Critical Care Nutrition Site for Patients and Providers
- Background
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Education, Training, & Certifications
- Clinical Pharmacology Fellowship, The University of Chicago 2000 - 2001
- Residency in Anesthesiology, The University of Chicago 1997 - 2000
- M.D., The University of Chicago 1996
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Previous Appointments & Affiliations
- Member of the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 2016 - 2020
- Instructor in the Department of Anesthesiology, Anesthesiology, Critical Care Medicine, Anesthesiology 2016 - 2017
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Leadership & Clinical Positions at Duke
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Director of Nutrition and TPN Team at Duke University Hospital
Associate Vice-Chair of Clinical Research for Anesthesiology
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Director of Nutrition and TPN Team at Duke University Hospital
- Recognition
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In the News
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JAN 18, 2023 School of Medicine Magnify -
JAN 7, 2022 Medical News-Life Sciences -
JUN 4, 2020 PR News Wire -
MAY 31, 2019 Royal College of Anesthesia -
NOV 12, 2018 Mastering Intensive Care Podcast -
NOV 10, 2018 DCRI Nutrition in Surgery Podcast -
AUG 19, 2018 TopMedTalks Podcast -
AUG 18, 2018 TopMedTalks Podcast -
AUG 17, 2018 TopMedTalks Podcast -
MAR 30, 2018 Outpatient Surgery -
FEB 28, 2018 Duke Clinical Research Center -
AUG 11, 2017 U.S. New and World Reports -
JUN 19, 2017 Modern Healthcare -
MAR 28, 2017 Critical Care Practitioner -
SEP 6, 2016 Popular Science -
SEP 6, 2016 Huffington Post -
SEP 2, 2016 Researchgate -
AUG 31, 2016 mBIOSPHERE
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Awards & Honors
- Clinical Nutrition Team of Distinction Award . American Society of Parenteral and Enteral Nutrition . March 2022
- George Blackburn Excellence in Nutrition Research Mentorship Award . American Society for Parenteral and Enteral Nutrition . April 2020
- Excellence in Nutrition Support Education Award – ASPEN Society . American Society of Parenteral and Enteral Nutrition . March 2020
- Faculty of Critical Care Medicine (FCCM) Elected Member. Society of Critical Care Medicine . January 2020
- Samuel Thompson Rowling Honorary Oration . Royal College of Anesthesiology. May 2019
- FASPEN. The American Society for Parenteral and Enteral Nutrition (ASPEN). March 2019
- Jeffrey Silverstein Award and Memorial Lecture for Humanism in Medicine . American Delirium Society. June 2016
- Academy of Mentors, Elected Member. Foundation for Anesthesia Education and Research . 2016
- Best Doctors in America: Critical Care. Best Doctors in America - voted by peer physicians. 2014
- Invited Member of European Society of Clinical Nutrition and Metabolic Care (ESPEN) Faculty. ESPEN Society. 2010
- Society of Critical Care Medicine (SCCM) Congress Co-Chairman. Society of Critical Care Medicine (SCCM). 2009
- Stanley Dudrick Honorary Award for Significant Lifetime Contribution to Research in Nutrition. American Society for Parenteral and Enteral Nutrition. 2008
- Lifetime Achievement Award . International Parenteral Nutrition Education and Methodology Advancement Society. 2007
- AUA Elected Member . Association of University Anesthesiologists (AUA). 2006
- Young Investigator Award of European Society of Parenteral and Enteral Nutrition (ESPEN) . European Society of Parenteral and Enteral Nutrition. 2005
- John M. Kinney International Award For General Nutrition 2004 (Award for Most Outstanding Work Directly Relevant to Field of General Nutrition. "Nutrition" Journal. 2004
- New Inventor of YEar. University of Colorado School of Medicine. 2003
- Outstanding Teacher of the Year Award. Department of Anesthesiology, University of Colorado . 2003
- Shock Society Young Investigator Award Finalist. Shock Society. 2001
- Alpha Omega Alpha Medical School Honor Society. University of Chicago Pritzker School of Medicine. 1995
- Student Research Award- Honorable Mention. American Gastroenterological Association (AGA). 1992
- USA Today Academic All-American Team. USA Today. 1992
- Expertise
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Subject Headings
- Anesthesiology
- Basal Metabolism
- COVID-19
- COVID-19 (Disease)
- Critical Care
- Glutamine
- Heat shock proteins
- Malnutrition
- Metabolism
- Microbiome
- Nutrition
- Nutrition Assessment
- Nutrition Disorders
- Nutrition Policy
- Nutrition Processes
- Nutrition Therapy
- Parenteral Nutrition
- Parenteral Nutrition Solutions
- Parenteral Nutrition, Home
- Parenteral Nutrition, Home Total
- Parenteral Nutrition, Total
- Parenteral feeding
- Perioperative Care
- Probiotics
- Protein-Energy Malnutrition
- Proteins in human nutrition
- Surgical diseases
- Surgical intensive care
- Surgical wound infections
- Therapeutics, Surgical
- Research
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Selected Grants
- Remotely Monitored, Mobile health-supported High Intensity Interval Training after COVID-19 Critical Illness (REMM HIIT-Covid19) awarded by National Institutes of Health 2021 - 2026
- UNC-Duke Collaborative Clinical Pharmacology Postdoctoral Training Program awarded by University of North Carolina - Chapel Hill 2016 - 2026
- Integrated Training in Anesthesiology Research awarded by National Institutes of Health 1996 - 2026
- Personalized Targeted Nutrition via StructurEd Nutrition Delivery Pathway to Improve Recovery of Physical Function in Trauma - SeND Home awarded by Department of Defense 2022 - 2026
- A Phase 3, Randomized, Double-Blind, Active and Placebo-Controlled Study on the Use of CUSA-081 for Dysfunctional Central Venous Access Devices (CVADs) awarded by Chiesi Farmaceutici SPA 2020 - 2024
- The Role of the IL-1 Receptor in the AKI to CKD transition awarded by National Institutes of Health 2019 - 2024
- CYCLE (Critical Care Cycling to Improve Lower Extremity Strength): An International, MultiCenter, Randomized Study of Early Cycle Ergometry for Mechanically Ventilated Patients awarded by McMaster University 2019 - 2024
- REmotely Monitored, Mobile-Health High Intensity Interval Training after Critical Care (REMM-HIIT) awarded by Society of Critical Care Medicine 2021 - 2024
- Evaluation of the enhanced Kangaroo feeding tube with IRIS technology for post-pyloric placement in critically ill patients: A prospective multicenter international cohort study. awarded by Royal Melbourne Hospital 2020 - 2024
- Metabolic Cart-Guided Early Parenteral Nutrition and Structured Nutrition Pathway In Acute Care Abdominal Surgery and Trauma to Decrease Underfeeding and Complications: The PASTDUe Nutrition EcoSystem Project awarded by Baxter Healthcare Corporation 2020 - 2023
- Utilization and Outcomes of Peptide-based versus other Tube Feeding Formulae among Surgical Critical Care Patients in the United States awarded by Abbott Nutrition 2020 - 2023
- Longitudinal Evaluation of Energy Expenditure in ICU Patients From Admission to Discharge Using A Novel Indirect Calorimeter: LEEP-Forward Trial awarded by Baxter Healthcare Corporation 2019 - 2023
- Incidence and role of severe micronutrient and vitamin deficiencies caused by continuous renal replacement therapy (CRRT) in critically ill patients awarded by Baxter Healthcare Corporation 2019 - 2023
- Right Ventricular Metabolic Dysregulation after Surgery for Heart Failure awarded by International Anesthesia Research Society 2021 - 2023
- (LEEP-ON) Longitudinal Energy Expenditure in the ICU and Post-ICU Phases in Obese and Non-Obese Hospitalized Patients awarded by American Society for Parenteral and Enteral Nutrition 2022
- Effect of Prebiotic Fiber-Enriched Enteral Feeding on the Microbiome in Trauma Patients awarded by Abbott Nutrition 2017 - 2022
- Targeting microbially-derived juvenile protective factors to resolve neuroinflammation and delirium awarded by National Institutes of Health 2019 - 2022
- Impact of SMOF Lipid on Clinical Outcomes Among Patients Receiving Total Parenteral Nutrition: An Interrupted Time Series Analysis awarded by Fresenius Kabi AG 2020 - 2021
- Abbott Nutritional Project awarded by Abbott Nutrition 2018 - 2021
- The Impact of Race and Socioeconomic Status on Malnutrition in Surgical Patients awarded by American Society for Parenteral and Enteral Nutrition 2020 - 2021
- Preoperative exercise and nutrition to improve perioperative outcomes (PREvENT) pilot awarded by Nutricia Research B.V. 2019 - 2021
- Takeda 954-2004 for the Prophylaxis and Treatment of Postop GI Dysfunction awarded by Takeda Pharmaceuticals North America Inc. 2019 - 2021
- CAPER Support for Paul Wischmeyer Salary awarded by Institute for Medical Research, Inc. 2020
- Preoperative exercise to improve vagal tone (PREVENT) study awarded by International Anesthesia Research Society 2019 - 2020
- CYCLE Pilot: A Pilot Randomized Study of Early Cycle Ergometry versus Routine Physiotherapy in Mechanically Ventilated Patients awarded by McMaster University 2017 - 2018
- Lyric IV LP101 in patients with enteral feeding intolerance awarded by Lyric Pharmaceuticals, Inc. 2016 - 2018
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External Relationships
- ART Medical
- Abbott Nutrition (Abbott Labs)
- Baxter Healthcare
- Cardinal Health, Inc.
- DSM biomedical
- Fresenius-Kabi
- MuscleSound
- Nestle Health Sciences
- Nutricia
- Takeda Pharmaceutical Co. Ltd.
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Ma, Qing, and Paul E. Wischmeyer. “Effects of glutamine and n-3 polyunsaturated fatty acid mixed lipid emulsion supplementation of parenteral nutrition on sepsis score and bacterial clearance in early experimental sepsis.” Clin Nutr Espen 54 (April 2023): 406–11. https://doi.org/10.1016/j.clnesp.2023.02.012.Full Text Link to Item
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Morrison, Chet, Carla M. Prado, Paul Wischmeyer, Robert G. Martindale, Jose Pimiento, Jennifer Katz, Jeffrey I. Mechanick, and Jayshil J. Patel. “Nutrition for the high-risk surgical patient, when they need it most: Question and answer session.” Jpen J Parenter Enteral Nutr 47 Suppl 1 (February 2023): S69–71. https://doi.org/10.1002/jpen.2442.Full Text Link to Item
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Prado, Carla M., Katherine L. Ford, M Cristina Gonzalez, Lisa C. Murnane, Chelsia Gillis, Paul E. Wischmeyer, Chet A. Morrison, and Dileep N. Lobo. “Nascent to novel methods to evaluate malnutrition and frailty in the surgical patient.” Jpen J Parenter Enteral Nutr 47 Suppl 1, no. Suppl 1 (February 2023): S54–68. https://doi.org/10.1002/jpen.2420.Full Text Link to Item
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Haines, Krista L., Tetsu Ohnuma, Charles Trujillo, Obanor Osamudiamen, Vijay Krishnamoorthy, Karthik Raghunathan, and Paul E. Wischmeyer. “Hospital change to mixed lipid emulsion from soybean oil-based lipid emulsion for parenteral nutrition in hospitalized and critically ill adults improves outcomes: a pre-post-comparative study.” Crit Care 26, no. 1 (October 18, 2022): 317. https://doi.org/10.1186/s13054-022-04194-8.Full Text Open Access Copy Link to Item
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Rigiroli, Francesca, Dylan Zhang, Jeroen Molinger, Yingqi Wang, Andrew Chang, Paul E. Wischmeyer, Brant A. Inman, and Rajan T. Gupta. “Automated versus manual analysis of body composition measures on computed tomography in patients with bladder cancer.” Eur J Radiol 154 (September 2022): 110413. https://doi.org/10.1016/j.ejrad.2022.110413.Full Text Link to Item
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Davies, T. W., R. J. J. van Gassel, M. van de Poll, J. Gunst, M. P. Casaer, K. B. Christopher, J. C. Preiser, et al. “Core outcome measures for clinical effectiveness trials of nutritional and metabolic interventions in critical illness: an international modified Delphi consensus study evaluation (CONCISE).” Crit Care 26, no. 1 (August 6, 2022): 240. https://doi.org/10.1186/s13054-022-04113-x.Full Text Link to Item
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Fah, Megan, Laura E. Van Althuis, Tetsu Ohnuma, Hilary M. Winthrop, Krista L. Haines, David G. A. Williams, Vijay Krishnamoorthy, Karthik Raghunathan, and Paul E. Wischmeyer. “Micronutrient deficiencies in critically ill patients receiving continuous renal replacement therapy.” Clin Nutr Espen 50 (August 2022): 247–54. https://doi.org/10.1016/j.clnesp.2022.05.008.Full Text Link to Item
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Lew, Meagan V., Yi Ren, Yen P. Lowder, Sharareh Siamakpour-Reihani, Sendhilnathan Ramalingam, Kristi M. Romero, Jillian C. Thompson, et al. “Geriatric Assessment Reveals Actionable Impairments in Hematopoietic Stem Cell Transplantation Candidates Age 18 to 80 Years.” Transplant Cell Ther 28, no. 8 (August 2022): 498.e1-498.e9. https://doi.org/10.1016/j.jtct.2022.05.018.Full Text Link to Item
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Martindale, Robert G., Stanislaw Klek, Zudin Puthucheary, Martin D. Rosenthal, Christian Stoppe, Arthur R. H. van Zanten, Dan L. Waitzberg, and Paul E. Wischmeyer. “Commentary on "Guidelines for the provision of nutrition support therapy in the adult critically ill patient: The American Society for Parenteral and Enteral Nutrition".” Jpen J Parenter Enteral Nutr 46, no. 6 (August 2022): 1223–25. https://doi.org/10.1002/jpen.2376.Full Text Link to Item
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Williams, David Ga, Solomon Aronson, Sutton Murray, Matt Fuller, Elizabeth Villalta, Krista L. Haines, and Paul E. Wischmeyer. “Validation of the perioperative nutrition screen for prediction of postoperative outcomes.” Jpen J Parenter Enteral Nutr 46, no. 6 (August 2022): 1307–15. https://doi.org/10.1002/jpen.2310.Full Text Link to Item
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Haines, Krista, Virginia Parker, Tetsu Ohnuma, Vijay Krishnamoorthy, Karthik Raghunathan, Suela Sulo, Kirk W. Kerr, Beth Y. Besecker, Bridget A. Cassady, and Paul E. Wischmeyer. “Role of Early Enteral Nutrition in Mechanically Ventilated COVID-19 Patients.” Crit Care Explor 4, no. 4 (April 2022): e0683. https://doi.org/10.1097/CCE.0000000000000683.Full Text Link to Item
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Wischmeyer, Paul. “The Critical Role of Nutrition and Exercise: Optimization in the Patient With Cancer.” J Adv Pract Oncol 13, no. 3 (April 2022): 270–74. https://doi.org/10.6004/jadpro.2022.13.3.18.Full Text Link to Item
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Williams, D. G. A., and P. E. Wischmeyer. “Nutrition Status Optimization for Improved Perioperative Outcomes.” Current Anesthesiology Reports 12, no. 1 (March 1, 2022): 59–64. https://doi.org/10.1007/s40140-021-00504-y.Full Text
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Preiser, Jean-Charles, Yaseen M. Arabi, Mette M. Berger, Michael Casaer, Stephen McClave, Juan C. Montejo-González, Sandra Peake, et al. “A guide to enteral nutrition in intensive care units: 10 expert tips for the daily practice.” Crit Care 25, no. 1 (December 14, 2021): 424. https://doi.org/10.1186/s13054-021-03847-4.Full Text Link to Item
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Eisa, Mohamed, Stephen A. McClave, Sally Suliman, and Paul Wischmeyer. “How Differences in the Disease Process of the COVID-19 Pandemic Pose Challenges to the Delivery of Critical Care Nutrition.” Curr Nutr Rep 10, no. 4 (December 2021): 288–99. https://doi.org/10.1007/s13668-021-00379-9.Full Text Link to Item
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Niederer, Laura E., Hilary Miller, Krista L. Haines, Jeroen Molinger, John Whittle, David B. MacLeod, Stephen A. McClave, and Paul E. Wischmeyer. “Prolonged progressive hypermetabolism during COVID-19 hospitalization undetected by common predictive energy equations.” Clin Nutr Espen 45 (October 2021): 341–50. https://doi.org/10.1016/j.clnesp.2021.07.021.Full Text Link to Item
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Robinson, Katie N., Bridget A. Cassady, Refaat A. Hegazi, and Paul E. Wischmeyer. “Preoperative carbohydrate loading in surgical patients with type 2 diabetes: Are concerns supported by data?” Clinical Nutrition Espen 45 (October 2021): 1–8. https://doi.org/10.1016/j.clnesp.2021.08.023.Full Text
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Cereda, Emanuele, Pere Clavé, Peter F. Collins, Anne Holdoway, and Paul E. Wischmeyer. “Recovery Focused Nutritional Therapy across the Continuum of Care: Learning from COVID-19.” Nutrients 13, no. 9 (September 21, 2021). https://doi.org/10.3390/nu13093293.Full Text Link to Item
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De Waele, Elisabeth, Joop Jonckheer, and Paul E. Wischmeyer. “Indirect calorimetry in critical illness: a new standard of care?” Curr Opin Crit Care 27, no. 4 (August 1, 2021): 334–43. https://doi.org/10.1097/MCC.0000000000000844.Full Text Link to Item
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Berger, Mette M., Marcus Broman, Lui Forni, Marlies Ostermann, Elisabeth De Waele, and Paul E. Wischmeyer. “Nutrients and micronutrients at risk during renal replacement therapy: a scoping review.” Curr Opin Crit Care 27, no. 4 (August 1, 2021): 367–77. https://doi.org/10.1097/MCC.0000000000000851.Full Text Link to Item
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Wischmeyer, Paul E. “Editorial: Objective measurement of nutrition and metabolism in the ICU: the future of personalized metabolic therapy.” Curr Opin Crit Care 27, no. 4 (August 1, 2021): 329–33. https://doi.org/10.1097/MCC.0000000000000848.Full Text Link to Item
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Tang, Helen, Lauren Bohannon, Meagan Lew, David Jensen, Sin-Ho Jung, Aaron Zhao, Anthony D. Sung, and Paul E. Wischmeyer. “Randomised, double-blind, placebo-controlled trial of Probiotics To Eliminate COVID-19 Transmission in Exposed Household Contacts (PROTECT-EHC): a clinical trial protocol.” Bmj Open 11, no. 5 (May 5, 2021): e047069. https://doi.org/10.1136/bmjopen-2020-047069.Full Text Open Access Copy Link to Item
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De Waele, Elisabeth, Julie Roth Jakubowski, Reto Stocker, and Paul E. Wischmeyer. “Review of evolution and current status of protein requirements and provision in acute illness and critical care.” Clin Nutr 40, no. 5 (May 2021): 2958–73. https://doi.org/10.1016/j.clnu.2020.12.032.Full Text Link to Item
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Wischmeyer, Paul E. “Overcoming challenges to enteral nutrition delivery in critical care.” Curr Opin Crit Care 27, no. 2 (April 1, 2021): 169–76. https://doi.org/10.1097/MCC.0000000000000801.Full Text Link to Item
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Wang, Yingqi, Andrew Chang, Wei Phin Tan, Joseph J. Fantony, Ajay Gopalakrishna, Gregory J. Barton, Paul E. Wischmeyer, Rajan T. Gupta, and Brant A. Inman. “Diet and Exercise Are not Associated with Skeletal Muscle Mass and Sarcopenia in Patients with Bladder Cancer.” Eur Urol Oncol 4, no. 2 (April 2021): 237–45. https://doi.org/10.1016/j.euo.2019.04.012.Full Text Open Access Copy Link to Item
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Wischmeyer, Paul E., Jeroen Molinger, and Krista Haines. “Point-Counterpoint: Indirect Calorimetry Is Essential for Optimal Nutrition Therapy in the Intensive Care Unit.” Nutr Clin Pract 36, no. 2 (April 2021): 275–81. https://doi.org/10.1002/ncp.10643.Full Text Link to Item
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Pu, Hong, Philippa T. Heighes, Fiona Simpson, Yaoli Wang, Zeping Liang, Paul Wischmeyer, Thomas J. Hugh, and Gordon S. Doig. “Early oral protein-containing diets following elective lower gastrointestinal tract surgery in adults: a meta-analysis of randomized clinical trials.” Perioper Med (Lond) 10, no. 1 (March 23, 2021): 10. https://doi.org/10.1186/s13741-021-00179-3.Full Text Link to Item
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Haines, Krista L., William Lao, Benjamin P. Nguyen, Vijay Krishnamoorthy, David Williams, Scott Gallagher, Suresh Agarwal, and Paul E. Wischmeyer. “Evaluation of malnutrition via modified GLIM criteria for in patients undergoing emergent gastrointestinal surgery.” Clin Nutr 40, no. 3 (March 2021): 1367–75. https://doi.org/10.1016/j.clnu.2020.08.026.Full Text Link to Item
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Williams, David G. A., Tetsu Ohnuma, Krista L. Haines, Vijay Krishnamoorthy, Karthik Raghunathan, Suela Sulo, Bridget A. Cassady, Refaat Hegazi, and Paul E. Wischmeyer. “Association between early postoperative nutritional supplement utilisation and length of stay in malnourished hip fracture patients.” Br J Anaesth 126, no. 3 (March 2021): 730–37. https://doi.org/10.1016/j.bja.2020.12.026.Full Text Link to Item
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Williams, David G. A., Tetsu Ohnuma, Vijay Krishnamoorthy, Karthik Raghunathan, Suela Sulo, Bridget A. Cassady, Refaat Hegazi, and Paul E. Wischmeyer. “Postoperative Utilization of Oral Nutrition Supplements in Surgical Patients in US Hospitals.” Jpen. Journal of Parenteral and Enteral Nutrition 45, no. 3 (March 2021): 596–606. https://doi.org/10.1002/jpen.1862.Full Text
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Gillis, Chelsia, Sarah J. Davies, Francesco Carli, Paul E. Wischmeyer, Stephen A. Wootton, Alan A. Jackson, Bernhard Riedel, Luise V. Marino, Denny Z. H. Levett, and Malcolm A. West. “Current Landscape of Nutrition Within Prehabilitation Oncology Research: A Scoping Review.” Front Nutr 8 (2021): 644723. https://doi.org/10.3389/fnut.2021.644723.Full Text Open Access Copy Link to Item
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Fudim, Marat, Yawar J. Qadri, Kamrouz Ghadimi, David B. MacLeod, Jeroen Molinger, Jonathan P. Piccini, John Whittle, Paul E. Wischmeyer, Manesh R. Patel, and Luis Ulloa. “Implications for Neuromodulation Therapy to Control Inflammation and Related Organ Dysfunction in COVID-19.” J Cardiovasc Transl Res 13, no. 6 (December 2020): 894–99. https://doi.org/10.1007/s12265-020-10031-6.Full Text Open Access Copy Link to Item
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Oshima, Taku, Marta Delsoglio, Yves M. Dupertuis, Pierre Singer, Elisabeth De Waele, Cecilia Veraar, Claudia-Paula Heidegger, et al. “The clinical evaluation of the new indirect calorimeter developed by the ICALIC project.” Clin Nutr 39, no. 10 (October 2020): 3105–11. https://doi.org/10.1016/j.clnu.2020.01.017.Full Text Link to Item
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Wischmeyer, Paul E., Oscar E. Suman, Rosemary Kozar, Steven E. Wolf, Jeroen Molinger, and Amy M. Pastva. “Role of anabolic testosterone agents and structured exercise to promote recovery in ICU survivors.” Curr Opin Crit Care 26, no. 5 (October 2020): 508–15. https://doi.org/10.1097/MCC.0000000000000757.Full Text Link to Item
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Whittle, John, Jeroen Molinger, David MacLeod, Krista Haines, Paul E. Wischmeyer, and Paul E. LEEP-COVID Study Group. “Persistent hypermetabolism and longitudinal energy expenditure in critically ill patients with COVID-19.” Crit Care 24, no. 1 (September 28, 2020): 581. https://doi.org/10.1186/s13054-020-03286-7.Full Text Open Access Copy Link to Item
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Williams, David G. A., Elizabeth Villalta, Solomon Aronson, Sutton Murray, Jeanna Blitz, Virginia Kosmos, Paul E. Wischmeyer, and Paul E. Duke Perioperative Enhancement Team (POET). “Tutorial: Development and Implementation of a Multidisciplinary Preoperative Nutrition Optimization Clinic.” Jpen J Parenter Enteral Nutr 44, no. 7 (September 2020): 1185–96. https://doi.org/10.1002/jpen.1824.Full Text Link to Item
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Grimberg, Dominic C., Ankeet Shah, Jeroen Molinger, John Whittle, Rajan T. Gupta, Paul E. Wischmeyer, Shelley R. McDonald, and Brant A. Inman. “Assessments of frailty in bladder cancer.” Urol Oncol 38, no. 9 (September 2020): 698–705. https://doi.org/10.1016/j.urolonc.2020.04.036.Full Text Open Access Copy Link to Item
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Molinger, Jeroen, Amy M. Pastva, John Whittle, and Paul E. Wischmeyer. “Novel approaches to metabolic assessment and structured exercise to promote recovery in ICU survivors.” Curr Opin Crit Care 26, no. 4 (August 2020): 369–78. https://doi.org/10.1097/MCC.0000000000000748.Full Text Open Access Copy Link to Item
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Ohnuma, Tetsu, Vijay Krishnamoorthy, Karthik Raghunathan, David G. A. Williams, Suela Sulo, Refaat Hegazi, and Paul E. Wischmeyer. “Overcoming confounding by indication in nutrition research using electronic healthcare data.” Clin Nutr 39, no. 4 (April 2020): 985–87. https://doi.org/10.1016/j.clnu.2020.01.024.Full Text Link to Item
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Williams, David G. A., and Paul E. Wischmeyer. “Perioperative Nutrition Care of Orthopedic Surgery Patient.” Tech Orthop 35, no. 1 (March 2020): 15–18. https://doi.org/10.1097/bto.0000000000000412.Full Text Link to Item
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Wischmeyer, Paul E., Rachael A. Mintz-Cole, Christine H. Baird, Kirk A. Easley, Addison K. May, Harry C. Sax, Kenneth A. Kudsk, et al. “Role of heat shock protein and cytokine expression as markers of clinical outcomes with glutamine-supplemented parenteral nutrition in surgical ICU patients.” Clin Nutr 39, no. 2 (February 2020): 563–73. https://doi.org/10.1016/j.clnu.2019.02.045.Full Text Link to Item
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Jonckheere, Wim, Michaël Mekeirele, Steven Hendrickx, Joop Jonckheer, Marc Diltoer, Idris Ghijselings, Matthias Raes, et al. “Percutaneous tracheostomy for long-term ventilated COVID-19-patients: rationale and first clinical-safe for all-experience.” Anaesthesiol Intensive Ther 52, no. 5 (2020): 366–72. https://doi.org/10.5114/ait.2020.101216.Full Text Link to Item
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Watson, John D., Tracy T. Urban, Suhong S. Tong, Jeanne Zenge, Ludmilla Khailova, Paul E. Wischmeyer, and Jesse A. Davidson. “Immediate Post-operative Enterocyte Injury, as Determined by Increased Circulating Intestinal Fatty Acid Binding Protein, Is Associated With Subsequent Development of Necrotizing Enterocolitis After Infant Cardiothoracic Surgery.” Front Pediatr 8 (2020): 267. https://doi.org/10.3389/fped.2020.00267.Full Text Open Access Copy Link to Item
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Wischmeyer, Paul E. “Enteral Nutrition Can Be Given to Patients on Vasopressors.” Crit Care Med 48, no. 1 (January 2020): 122–25. https://doi.org/10.1097/CCM.0000000000003965.Full Text Link to Item
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Williams, David G. A., Tetsu Ohnuma, Vijay Krishnamoorthy, Karthik Raghunathan, Suela Sulo, Bridget A. Cassady, Refaat Hegazi, and Paul E. Wischmeyer. “Impact of early postoperative oral nutritional supplement utilization on clinical outcomes in colorectal surgery.” Perioper Med (Lond) 9 (2020): 29. https://doi.org/10.1186/s13741-020-00160-6.Full Text Open Access Copy Link to Item
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McClave, Stephen A., Paul E. Wischmeyer, Keith R. Miller, and Arthur R. H. van Zanten. “Mitochondrial Dysfunction in Critical Illness: Implications for Nutritional Therapy.” Curr Nutr Rep 8, no. 4 (December 2019): 363–73. https://doi.org/10.1007/s13668-019-00296-y.Full Text Link to Item
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Zanten, Arthur Raymond Hubert van, Elisabeth De Waele, and Paul Edmund Wischmeyer. “Nutrition therapy and critical illness: practical guidance for the ICU, post-ICU, and long-term convalescence phases.” Crit Care 23, no. 1 (November 21, 2019): 368. https://doi.org/10.1186/s13054-019-2657-5.Full Text Open Access Copy Link to Item
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Wischmeyer, Paul E. “Glutamine in Burn Injury.” Nutr Clin Pract 34, no. 5 (October 2019): 681–87. https://doi.org/10.1002/ncp.10362.Full Text Link to Item
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Wernerman, Jan, Kenneth B. Christopher, Djillali Annane, Michael P. Casaer, Craig M. Coopersmith, Adam M. Deane, Elisabeth De Waele, et al. “Metabolic support in the critically ill: a consensus of 19.” Crit Care 23, no. 1 (September 18, 2019): 318. https://doi.org/10.1186/s13054-019-2597-0.Full Text Link to Item
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Wischmeyer, Paul E. “The glutamine debate in surgery and critical care.” Curr Opin Crit Care 25, no. 4 (August 2019): 322–28. https://doi.org/10.1097/MCC.0000000000000633.Full Text Link to Item
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Williams, David G. A., Jeroen Molinger, and Paul E. Wischmeyer. “The malnourished surgery patient: a silent epidemic in perioperative outcomes?” Curr Opin Anaesthesiol 32, no. 3 (June 2019): 405–11. https://doi.org/10.1097/ACO.0000000000000722.Full Text Link to Item
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Bottiger, Brandi A., Alina Nicoara, Laurie D. Snyder, Paul E. Wischmeyer, Jacob N. Schroder, Chetan B. Patel, Mani A. Daneshmand, Robert N. Sladen, and Kamrouz Ghadimi. “Frailty in the End-Stage Lung Disease or Heart Failure Patient: Implications for the Perioperative Transplant Clinician.” J Cardiothorac Vasc Anesth 33, no. 5 (May 2019): 1382–92. https://doi.org/10.1053/j.jvca.2018.08.002.Full Text Link to Item
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Davidson, Jesse A., Tracy T. Urban, Suhong Tong, Aline Maddux, Gerald Hill, Benjamin S. Frank, John D. Watson, James Jaggers, Eric A. F. Simões, and Paul Wischmeyer. “Alkaline Phosphatase Activity and Endotoxemia After Infant Cardiothoracic Surgery.” Shock 51, no. 3 (March 2019): 328–36. https://doi.org/10.1097/SHK.0000000000001162.Full Text Link to Item
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Davison, James M., and Paul E. Wischmeyer. “Probiotic and synbiotic therapy in the critically ill: State of the art.” Nutrition 59 (March 2019): 29–36. https://doi.org/10.1016/j.nut.2018.07.017.Full Text Link to Item
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Fierro, Michael A., Eric I. Ehieli, Mary Cooter, Austin Traylor, Mark Stafford-Smith, Madhav Swaminathan, and Madhav Duke Critical Care Outcomes Research Endeavors (C-CORE) Group. “Renal Angina Is a Sensitive, but Nonspecific Identifier of Postcardiac Surgery Acute Kidney Injury.” J Cardiothorac Vasc Anesth 33, no. 2 (February 2019): 357–64. https://doi.org/10.1053/j.jvca.2018.07.017.Full Text Link to Item
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Gillis, C., and P. E. Wischmeyer. “Pre-operative nutrition and the elective surgical patient: why, how and what?” Anaesthesia 74 Suppl 1 (January 2019): 27–35. https://doi.org/10.1111/anae.14506.Full Text Open Access Copy Link to Item
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Wischmeyer, Paul E., Michelle M. McMoon, Nathan H. Waldron, and Elizabeth J. Dye. “Successful Identification of Anatomical Markers and Placement of Feeding Tubes in Critically Ill Patients via Camera-Assisted Technology with Real-Time Video Guidance.” Jpen J Parenter Enteral Nutr 43, no. 1 (January 2019): 118–25. https://doi.org/10.1002/jpen.1313.Full Text Link to Item
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Davidson, Jesse A., Zachary Pfeifer, Benjamin Frank, Suhong Tong, Tracy T. Urban, Paul A. Wischmeyer, Peter Mourani, Bruce Landeck, Uwe Christians, and Jelena Klawitter. “Metabolomic Fingerprinting of Infants Undergoing Cardiopulmonary Bypass: Changes in Metabolic Pathways and Association With Mortality and Cardiac Intensive Care Unit Length of Stay.” J Am Heart Assoc 7, no. 24 (December 18, 2018): e010711. https://doi.org/10.1161/JAHA.118.010711.Full Text Link to Item
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Whittle, John, Paul E. Wischmeyer, Michael P. W. Grocott, and Timothy E. Miller. “Surgical Prehabilitation: Nutrition and Exercise.” Anesthesiol Clin 36, no. 4 (December 2018): 567–80. https://doi.org/10.1016/j.anclin.2018.07.013.Full Text Link to Item
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Wischmeyer, P. E., F. Carli, and D. C. Evans. “American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Nutrition Screening and Therapy Within a Surgical Enhanced Recovery Pathway (vol 126, pg 1883, 2018).” Anesthesia and Analgesia 127, no. 5 (November 1, 2018): E95–E95.Link to Item
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Gopalakrishna, Ajay, Andrew Chang, Thomas A. Longo, Joseph J. Fantony, Michael R. Harrison, Paul E. Wischmeyer, and Brant A. Inman. “Dietary patterns and health-related quality of life in bladder cancer survivors.” Urol Oncol 36, no. 10 (October 2018): 469.e21-469.e29. https://doi.org/10.1016/j.urolonc.2018.06.001.Full Text Link to Item
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Abola, Ramon E., Elliott Bennett-Guerrero, Michael L. Kent, Liane S. Feldman, Julio F. Fiore, Andrew D. Shaw, Julie K. M. Thacker, et al. “American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Patient-Reported Outcomes in an Enhanced Recovery Pathway.” Anesth Analg 126, no. 6 (June 2018): 1874–82. https://doi.org/10.1213/ANE.0000000000002758.Full Text Open Access Copy Link to Item
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Hedrick, Traci L., Matthew D. McEvoy, Michael Monty G. Mythen, Roberto Bergamaschi, Ruchir Gupta, Stefan D. Holubar, Anthony J. Senagore, et al. “American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Postoperative Gastrointestinal Dysfunction Within an Enhanced Recovery Pathway for Elective Colorectal Surgery.” Anesth Analg 126, no. 6 (June 2018): 1896–1907. https://doi.org/10.1213/ANE.0000000000002742.Full Text Open Access Copy Link to Item
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Russell, Mary K., and Paul E. Wischmeyer. “Supplemental Parenteral Nutrition: Review of the Literature and Current Nutrition Guidelines.” Nutr Clin Pract 33, no. 3 (June 2018): 359–69. https://doi.org/10.1002/ncp.10096.Full Text Link to Item
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Wischmeyer, Paul E., Franco Carli, David C. Evans, Sarah Guilbert, Rosemary Kozar, Aurora Pryor, Robert H. Thiele, et al. “American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Nutrition Screening and Therapy Within a Surgical Enhanced Recovery Pathway.” Anesth Analg 126, no. 6 (June 2018): 1883–95. https://doi.org/10.1213/ANE.0000000000002743.Full Text Open Access Copy Link to Item
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Persson, Jessica N., Christine H. Baird, Suhong Tong, Tracy T. Urban, Jelena Klawitter, Paul E. Wischmeyer, and Jesse A. Davidson. “Infant cardiopulmonary bypass: CD73 kinetics, association with clinical outcomes, and influence on serum adenosine production capacity.” Pediatr Res 83, no. 4 (April 2018): 858–65. https://doi.org/10.1038/pr.2017.325.Full Text Link to Item
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Aronson, Solomon, Julie Westover, Nicole Guinn, Tracy Setji, Paul Wischmeyer, Padma Gulur, Thomas Hopkins, et al. “A Perioperative Medicine Model for Population Health: An Integrated Approach for an Evolving Clinical Science.” Anesth Analg 126, no. 2 (February 2018): 682–90. https://doi.org/10.1213/ANE.0000000000002606.Full Text Link to Item
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Wischmeyer, Paul E. “Nutrition Therapy in Sepsis.” Crit Care Clin 34, no. 1 (January 2018): 107–25. https://doi.org/10.1016/j.ccc.2017.08.008.Full Text Link to Item
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McDonald, Daniel, Embriette Hyde, Justine W. Debelius, James T. Morton, Antonio Gonzalez, Gail Ackermann, Alexander A. Aksenov, et al. “American Gut: an Open Platform for Citizen Science Microbiome Research.” Msystems 3, no. 3 (2018). https://doi.org/10.1128/mSystems.00031-18.Full Text Link to Item
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Marini, John J., Daniel De Backer, Can Ince, Mervyn Singer, Frank Van Haren, Martin Westphal, and Paul Wischmeyer. “Seven unconfirmed ideas to improve future ICU practice.” Crit Care 21, no. Suppl 3 (December 28, 2017): 315. https://doi.org/10.1186/s13054-017-1904-x.Full Text Open Access Copy Link to Item
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Wischmeyer, Paul E. “Tailoring nutrition therapy to illness and recovery.” Crit Care 21, no. Suppl 3 (December 28, 2017): 316. https://doi.org/10.1186/s13054-017-1906-8.Full Text Open Access Copy Link to Item
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Khailova, Ludmila, Christine H. Baird, Aubri A. Rush, Christopher Barnes, and Paul E. Wischmeyer. “Lactobacillus rhamnosus GG treatment improves intestinal permeability and modulates inflammatory response and homeostasis of spleen and colon in experimental model of Pseudomonas aeruginosa pneumonia.” Clin Nutr 36, no. 6 (December 2017): 1549–57. https://doi.org/10.1016/j.clnu.2016.09.025.Full Text Link to Item
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Davidson, Jesse A., Tracy T. Urban, Christine Baird, Suhong Tong, Alan Woodruff, Mark Twite, James Jaggers, Eric A. F. Simões, and Paul Wischmeyer. “Alkaline Phosphatase in Infant Cardiopulmonary Bypass: Kinetics and Relationship to Organ Injury and Major Cardiovascular Events.” J Pediatr 190 (November 2017): 49-55.e2. https://doi.org/10.1016/j.jpeds.2017.07.035.Full Text Link to Item
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Wischmeyer, Paul E., Zudin Puthucheary, Iñigo San Millán, Daniel Butz, and Michael P. W. Grocott. “Muscle mass and physical recovery in ICU: innovations for targeting of nutrition and exercise.” Curr Opin Crit Care 23, no. 4 (August 2017): 269–78. https://doi.org/10.1097/MCC.0000000000000431.Full Text Link to Item
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Wischmeyer, Paul E., Michel Hasselmann, Christine Kummerlen, Rosemary Kozar, Demetrios James Kutsogiannis, Constantine J. Karvellas, Beth Besecker, et al. “A randomized trial of supplemental parenteral nutrition in underweight and overweight critically ill patients: the TOP-UP pilot trial.” Crit Care 21, no. 1 (June 9, 2017): 142. https://doi.org/10.1186/s13054-017-1736-8.Full Text Open Access Copy Link to Item
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Williams, J. D., and Paul E. Wischmeyer. “Assessment of perioperative nutrition practices and attitudes-A national survey of colorectal and GI surgical oncology programs.” Am J Surg 213, no. 6 (June 2017): 1010–18. https://doi.org/10.1016/j.amjsurg.2016.10.008.Full Text Link to Item
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Manzanares, William, Pascal L. Langlois, and Paul E. Wischmeyer. “Restoring the Microbiome in Critically Ill Patients: Are Probiotics Our True Friends When We Are Seriously Ill?” Jpen J Parenter Enteral Nutr 41, no. 4 (May 2017): 530–33. https://doi.org/10.1177/0148607117700572.Full Text Link to Item
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Manzanares, William, and Paul E. Wischmeyer. “Response to "Reassessing the death risk related to probiotics in critically ill patients".” Crit Care 21, no. 1 (February 27, 2017): 43. https://doi.org/10.1186/s13054-017-1618-0.Full Text Link to Item
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Manzanares, William, and Paul E. Wischmeyer. “Erratum to: Probiotic and synbiotic therapy in critical illness: a systematic review and meta-analysis.” Crit Care 21, no. 1 (February 27, 2017): 42. https://doi.org/10.1186/s13054-017-1622-4.Full Text Link to Item
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Morrow, Lee E., and Paul Wischmeyer. “Blurred Lines: Dysbiosis and Probiotics in the ICU.” Chest 151, no. 2 (February 2017): 492–99. https://doi.org/10.1016/j.chest.2016.10.006.Full Text Link to Item
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Arora, Rakesh C., Paul E. Wischmeyer, and Rohit K. Singal. “Extracorporeal membrane oxygenation postcardiotomy: "With great power comes great responsibility".” J Thorac Cardiovasc Surg 153, no. 1 (January 2017): 102–3. https://doi.org/10.1016/j.jtcvs.2016.09.065.Full Text Open Access Copy Link to Item
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Heyland, Daren K., Paul Wischmeyer, Marc G. Jeschke, Lucy Wibbenmeyer, Alexis F. Turgeon, Henry T. Stelfox, Andrew G. Day, and Dominique Garrel. “A RandomizEd trial of ENtERal Glutamine to minimIZE thermal injury (The RE-ENERGIZE Trial): a clinical trial protocol.” Scars Burn Heal 3 (2017): 2059513117745241. https://doi.org/10.1177/2059513117745241.Full Text Link to Item
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Puthucheary, Zudin A., and Paul Wischmeyer. “Predicting critical illness mortality and personalizing therapy: moving to multi-dimensional data.” Critical Care (London, England) 21, no. 1 (January 2017): 20. https://doi.org/10.1186/s13054-016-1597-6.Full Text
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West, Malcolm A., Paul E. Wischmeyer, and Michael P. W. Grocott. “Prehabilitation and Nutritional Support to Improve Perioperative Outcomes.” Curr Anesthesiol Rep 7, no. 4 (2017): 340–49. https://doi.org/10.1007/s40140-017-0245-2.Full Text Link to Item
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Manzanares, William, Margot Lemieux, Pascal L. Langlois, and Paul E. Wischmeyer. “Probiotic and synbiotic therapy in critical illness: a systematic review and meta-analysis.” Crit Care 19 (August 19, 2016): 262. https://doi.org/10.1186/s13054-016-1434-y.Full Text Open Access Copy Link to Item
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Oshima, Taku, Nicolaas E. Deutz, Gordon Doig, Paul E. Wischmeyer, and Claude Pichard. “Protein-energy nutrition in the ICU is the power couple: A hypothesis forming analysis.” Clin Nutr 35, no. 4 (August 2016): 968–74. https://doi.org/10.1016/j.clnu.2015.10.016.Full Text Link to Item
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Wischmeyer, Paul E. “Are we creating survivors…or victims in critical care? Delivering targeted nutrition to improve outcomes.” Curr Opin Crit Care 22, no. 4 (August 2016): 279–84. https://doi.org/10.1097/MCC.0000000000000332.Full Text Open Access Copy Link to Item
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Wischmeyer, Paul E., Daniel McDonald, and Rob Knight. “Role of the microbiome, probiotics, and 'dysbiosis therapy' in critical illness.” Curr Opin Crit Care 22, no. 4 (August 2016): 347–53. https://doi.org/10.1097/MCC.0000000000000321.Full Text Open Access Copy Link to Item
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Ziegler, Thomas R., Addison K. May, Gautam Hebbar, Kirk A. Easley, Daniel P. Griffith, Nisha Dave, Bryan R. Collier, et al. “Efficacy and Safety of Glutamine-supplemented Parenteral Nutrition in Surgical ICU Patients: An American Multicenter Randomized Controlled Trial.” Ann Surg 263, no. 4 (April 2016): 646–55. https://doi.org/10.1097/SLA.0000000000001487.Full Text Link to Item
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Davidson, Jesse A., Tracy Urban, Suhong Tong, Mark Twite, Alan Woodruff, Paul E. Wischmeyer, and Jelena Klawitter. “Alkaline Phosphatase, Soluble Extracellular Adenine Nucleotides, and Adenosine Production after Infant Cardiopulmonary Bypass.” Plos One 11, no. 7 (2016): e0158981. https://doi.org/10.1371/journal.pone.0158981.Full Text Link to Item
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McDonald, Daniel, Gail Ackermann, Ludmila Khailova, Christine Baird, Daren Heyland, Rosemary Kozar, Margot Lemieux, et al. “Extreme Dysbiosis of the Microbiome in Critical Illness.” Msphere 1, no. 4 (2016). https://doi.org/10.1128/mSphere.00199-16.Full Text Link to Item
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Xue, Hongyu, Wenhua Ren, Melanie Denkinger, Ewald Schlotzer, and Paul E. Wischmeyer. “Nutrition Modulation of Cardiotoxicity and Anticancer Efficacy Related to Doxorubicin Chemotherapy by Glutamine and ω-3 Polyunsaturated Fatty Acids.” Jpen J Parenter Enteral Nutr 40, no. 1 (January 2016): 52–66. https://doi.org/10.1177/0148607115581838.Full Text Link to Item
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Davidson, Jesse, Tracy T. Urban, Suhong Tong, Mark Twite, Christine Baird, Ludmila Khailova, James Jaggers, and Paul Wischmeyer. “Alkaline Phosphatase Activity After Infant Cardiac Surgery: Kinetics and Association With Post-operative Cardiovascular Support.” Circulation 132 (November 10, 2015).Link to Item
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Wischmeyer, Paul. “Glutamine Supplementation in Parenteral Nutrition and Intensive Care Unit Patients: Are We Throwing the Baby Out With the Bathwater?” Jpen J Parenter Enteral Nutr 39, no. 8 (November 2015): 893–97. https://doi.org/10.1177/0148607115593792.Full Text Link to Item
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Wischmeyer, Paul E. “Ensuring Optimal Survival and Post-ICU Quality of Life in High-Risk ICU Patients: Permissive Underfeeding Is Not Safe!.” Crit Care Med 43, no. 8 (August 2015): 1769–72. https://doi.org/10.1097/CCM.0000000000001098.Full Text Link to Item
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Heyland, Daren K., Gunnar Elke, Deborah Cook, Mette M. Berger, Paul E. Wischmeyer, Martin Albert, John Muscedere, Gwynne Jones, Andrew G. Day, and Andrew G. Canadian Critical Care Trials Group. “Glutamine and antioxidants in the critically ill patient: a post hoc analysis of a large-scale randomized trial.” Jpen J Parenter Enteral Nutr 39, no. 4 (May 2015): 401–9. https://doi.org/10.1177/0148607114529994.Full Text Link to Item
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Preiser, Jean-Charles, Arthur R. H. van Zanten, Mette M. Berger, Gianni Biolo, Michael P. Casaer, Gordon S. Doig, Richard D. Griffiths, et al. “Metabolic and nutritional support of critically ill patients: consensus and controversies.” Crit Care 19, no. 1 (January 29, 2015): 35. https://doi.org/10.1186/s13054-015-0737-8.Full Text Open Access Copy Link to Item
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Fernandez-Bustamante, Ana, Amanda Agazio, Paul Wilson, Nancy Elkins, Luke Domaleski, Qianbin He, Kaily A. Baer, Angela F. D. Moss, Paul E. Wischmeyer, and John E. Repine. “Brief Glutamine Pretreatment Increases Alveolar Macrophage CD163/Heme Oxygenase-1/p38-MAPK Dephosphorylation Pathway and Decreases Capillary Damage but Not Neutrophil Recruitment in IL-1/LPS-Insufflated Rats.” Plos One 10, no. 7 (2015): e0130764. https://doi.org/10.1371/journal.pone.0130764.Full Text Open Access Copy Link to Item
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Marini, John J., Luciano Gattinoni, Can Ince, Sibylle Kozek-Langenecker, Ravindra L. Mehta, Claude Pichard, Martin Westphal, Paul Wischmeyer, and Jean-Louis Vincent. “A few of our favorite unconfirmed ideas.” Crit Care 19 Suppl 3, no. Suppl 3 (2015): S1. https://doi.org/10.1186/cc14719.Full Text Open Access Copy Link to Item
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Wischmeyer, Paul E. “Alternative lipid emulsions as a new standard of care for total parenteral nutrition: finally available in the United States?” Crit Care Med 43, no. 1 (January 2015): 230–31. https://doi.org/10.1097/CCM.0000000000000757.Full Text Link to Item
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Wischmeyer, Paul E., and Inigo San-Millan. “Winning the war against ICU-acquired weakness: new innovations in nutrition and exercise physiology.” Crit Care 19 Suppl 3, no. Suppl 3 (2015): S6. https://doi.org/10.1186/cc14724.Full Text Link to Item
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Lakdawalla, D., Snider J. Thornton, D. Perlroth, C. LaVallee, M. T. Linthicum, T. J. Philipson, J. Partridge, and P. Wischmeyer. “Effect of Oral Nutritional Supplements On Hospital Outcomes in Patients Aged 65+ With Congestive Heart Failure.” Value Health 17, no. 7 (November 2014): A503. https://doi.org/10.1016/j.jval.2014.08.1518.Full Text Link to Item
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Lakdawalla, Darius N., Julia Thornton Snider, Daniella J. Perlroth, Chris LaVallee, Mark T. Linthicum, Tomas J. Philipson, Jamie S. Partridge, and Paul E. Wischmeyer. “Can Oral Nutritional Supplements Improve Medicare Patient Outcomes in the Hospital?” Forum Health Econ Policy 17, no. 2 (September 1, 2014): 131–51. https://doi.org/10.1515/fhep-2014-0011.Full Text Link to Item
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Lakdawalla, Darius N., Julia Thornton Snider, Mark T. Linthicum, Daniella J. Perlroth, Chris LaVallee, Tomas J. Philipson, Jamie S. Partridge, and Paul E. Wischmeyer. “Can Oral Nutritional Supplements Improve Medicare Patient Outcomes in the Hospital?” Forum for Health Economics & Policy 17, no. 2 (September 2014): 21–21.
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Mourtzakis, Marina, and Paul Wischmeyer. “Bedside ultrasound measurement of skeletal muscle.” Curr Opin Clin Nutr Metab Care 17, no. 5 (September 2014): 389–95. https://doi.org/10.1097/MCO.0000000000000088.Full Text Link to Item
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Tillquist, Maggie, Demetrios J. Kutsogiannis, Paul E. Wischmeyer, Christine Kummerlen, Roger Leung, Daniel Stollery, Constantine J. Karvellas, et al. “Bedside ultrasound is a practical and reliable measurement tool for assessing quadriceps muscle layer thickness.” Jpen J Parenter Enteral Nutr 38, no. 7 (September 2014): 886–90. https://doi.org/10.1177/0148607113501327.Full Text Link to Item
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Wischmeyer, Paul E., Rupinder Dhaliwal, Michele McCall, Thomas R. Ziegler, and Daren K. Heyland. “Parenteral glutamine supplementation in critical illness: a systematic review.” Crit Care 18, no. 2 (April 18, 2014): R76. https://doi.org/10.1186/cc13836.Full Text Link to Item
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Glenn, Jacquelyn O’ Herrin, and Paul E. Wischmeyer. “Enteral fish oil in critical illness: perspectives and systematic review.” Curr Opin Clin Nutr Metab Care 17, no. 2 (March 2014): 116–23. https://doi.org/10.1097/MCO.0000000000000039.Full Text Link to Item
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Khailova, Ludmila, Benjamin Petrie, Christine H. Baird, Jessica A. Dominguez Rieg, and Paul E. Wischmeyer. “Lactobacillus rhamnosus GG and Bifidobacterium longum attenuate lung injury and inflammatory response in experimental sepsis.” Plos One 9, no. 5 (2014): e97861. https://doi.org/10.1371/journal.pone.0097861.Full Text Link to Item
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Khailova, Ludmila, Christine H. Baird, Aubri A. Rush, Eoin N. McNamee, and Paul E. Wischmeyer. “Lactobacillus rhamnosus GG improves outcome in experimental pseudomonas aeruginosa pneumonia: potential role of regulatory T cells.” Shock 40, no. 6 (December 2013): 496–503. https://doi.org/10.1097/SHK.0000000000000066.Full Text Link to Item
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Wilson, Joel, David Higgins, Haley Hutting, Natalie Serkova, Christine Baird, Ludmila Khailova, Kelly Queensland, Zung Vu Tran, Lindsay Weitzel, and Paul E. Wischmeyer. “Early propranolol treatment induces lung heme-oxygenase-1, attenuates metabolic dysfunction, and improves survival following experimental sepsis.” Crit Care 17, no. 5 (September 10, 2013): R195. https://doi.org/10.1186/cc12889.Full Text Open Access Copy Link to Item
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Braga, Marco, Paul E. Wischmeyer, John Drover, and Daren K. Heyland. “Clinical evidence for pharmaconutrition in major elective surgery.” Jpen J Parenter Enteral Nutr 37, no. 5 Suppl (September 2013): 66S-72S. https://doi.org/10.1177/0148607113494406.Full Text Link to Item
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McClave, Stephen A., Rosemary Kozar, Robert G. Martindale, Daren K. Heyland, Marco Braga, Francesco Carli, John W. Drover, et al. “Summary points and consensus recommendations from the North American Surgical Nutrition Summit.” Jpen J Parenter Enteral Nutr 37, no. 5 Suppl (September 2013): 99S-105S. https://doi.org/10.1177/0148607113495892.Full Text Link to Item
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Miller, Keith R., Paul E. Wischmeyer, Beth Taylor, and Stephen A. McClave. “An evidence-based approach to perioperative nutrition support in the elective surgery patient.” Jpen J Parenter Enteral Nutr 37, no. 5 Suppl (September 2013): 39S-50S. https://doi.org/10.1177/0148607113493928.Full Text Link to Item
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Pierre, Joseph F., Aaron F. Heneghan, Christy M. Lawson, Paul E. Wischmeyer, Rosemary A. Kozar, and Kenneth A. Kudsk. “Pharmaconutrition review: physiological mechanisms.” Jpen J Parenter Enteral Nutr 37, no. 5 Suppl (September 2013): 51S-65S. https://doi.org/10.1177/0148607113493326.Full Text Link to Item
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Heyland, Daren K., and Paul E. Wischmeyer. “Does artificial nutrition improve outcome of critical illness? An alternative viewpoint!.” Crit Care 17, no. 4 (August 27, 2013): 324. https://doi.org/10.1186/cc12701.Full Text Link to Item
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Heyland, Daren, Paul E. Wischmeyer, Andrew G. Day, and Andrew G. Canadian Clinical Care Trials Group. “Glutamine and antioxidants in critically ill patients.” N Engl J Med 369, no. 5 (August 1, 2013): 484–85. https://doi.org/10.1056/NEJMc1306658.Full Text Link to Item
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Cheng, S., C. Baird, E. Luzier, K. N. Nordenholz, D. Matero, M. McCarter, N. Pearlman, C. Gajdos, Z. Tran, and P. Wischmeyer. “Association of perioperative inflammation and coagulation status with delayed VTE after major surgery.” Journal of Thrombosis and Haemostasis 11 (July 1, 2013): 1009–1009.Link to Item
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Khailova, Ludmila, Daniel N. Frank, Jessica A. Dominguez, and Paul E. Wischmeyer. “Probiotic administration reduces mortality and improves intestinal epithelial homeostasis in experimental sepsis.” Anesthesiology 119, no. 1 (July 2013): 166–77. https://doi.org/10.1097/ALN.0b013e318291c2fc.Full Text Link to Item
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Niederlechner, Stefanie, Christine Baird, and Paul E. Wischmeyer. “P38MAP kinase, but not phosphoinositol-3 kinase, signal downstream of glutamine-mediated fibronectin-integrin signaling after intestinal injury.” Nutr J 12, no. 1 (June 21, 2013): 88. https://doi.org/10.1186/1475-2891-12-88.Full Text Link to Item
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Heyland, Daren, John Muscedere, Paul E. Wischmeyer, Deborah Cook, Gwynne Jones, Martin Albert, Gunnar Elke, Mette M. Berger, Andrew G. Day, and Andrew G. Canadian Critical Care Trials Group. “A randomized trial of glutamine and antioxidants in critically ill patients.” N Engl J Med 368, no. 16 (April 18, 2013): 1489–97. https://doi.org/10.1056/NEJMoa1212722.Full Text Link to Item
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Niederlechner, Stefanie, Christine Baird, Benjamin Petrie, Erhard Wischmeyer, and Paul E. Wischmeyer. “Epidermal growth factor receptor expression and signaling are essential in glutamine's cytoprotective mechanism in heat-stressed intestinal epithelial-6 cells.” Am J Physiol Gastrointest Liver Physiol 304, no. 5 (March 1, 2013): G543–52. https://doi.org/10.1152/ajpgi.00418.2012.Full Text Link to Item
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Weijs, Peter J. M., and Paul E. Wischmeyer. “Optimizing energy and protein balance in the ICU.” Curr Opin Clin Nutr Metab Care 16, no. 2 (March 2013): 194–201. https://doi.org/10.1097/MCO.0b013e32835bdf7e.Full Text Link to Item
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Baird, Christine H., Stefanie Niederlechner, Ryan Beck, Alyssa R. Kallweit, and Paul E. Wischmeyer. “L-Threonine induces heat shock protein expression and decreases apoptosis in heat-stressed intestinal epithelial cells.” Nutrition 29, no. 11–12 (2013): 1404–11. https://doi.org/10.1016/j.nut.2013.05.017.Full Text Link to Item
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Marini, John J., Jean-Louis Vincent, Paul Wischmeyer, Mervyn Singer, Luciano Gattinoni, Can Ince, and Tong Joo Gan. “Our favorite unproven ideas for future critical care.” Crit Care 17 Suppl 1, no. Suppl 1 (2013): S9. https://doi.org/10.1186/cc11507.Full Text Link to Item
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Weitzel, Lindsay B., Amrut V. Ambardekar, Andreas Brieke, Joseph C. Cleveland, Natalie J. Serkova, Paul E. Wischmeyer, and Brian D. Lowes. “Left ventricular assist device effects on metabolic substrates in the failing heart.” Plos One 8, no. 4 (2013): e60292. https://doi.org/10.1371/journal.pone.0060292.Full Text Link to Item
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Wischmeyer, Paul E. “The evolution of nutrition in critical care: how much, how soon?” Crit Care 17 Suppl 1, no. Suppl 1 (2013): S7. https://doi.org/10.1186/cc11505.Full Text Link to Item
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Wischmeyer, Paul E., Lindsay Weitzel, Katie Mercaldi, Gary Zaloga, Mary Hise, Alessandro Pontes-Arruda, and Robin Turpin. “Characteristics and current practice of parenteral nutrition in hospitalized patients.” Jpen J Parenter Enteral Nutr 37, no. 1 (January 2013): 56–67. https://doi.org/10.1177/0148607112444448.Full Text Link to Item
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Higgins, David M., Paul E. Wischmeyer, Kelly M. Queensland, Stefan H. Sillau, Alexandra J. Sufit, and Daren K. Heyland. “Relationship of vitamin D deficiency to clinical outcomes in critically ill patients.” Jpen J Parenter Enteral Nutr 36, no. 6 (November 2012): 713–20. https://doi.org/10.1177/0148607112444449.Full Text Link to Item
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Pontes-Arruda, Alessandro, Gary Zaloga, Paul Wischmeyer, Robin Turpin, Frank X. Liu, and Catherine Mercaldi. “Is there a difference in bloodstream infections in critically ill patients associated with ready-to-use versus compounded parenteral nutrition?” Clin Nutr 31, no. 5 (October 2012): 728–34. https://doi.org/10.1016/j.clnu.2012.03.004.Full Text Link to Item
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Kallweit, Alyssa R., Christine Hamiel Baird, Diana K. Stutzman, and Paul E. Wischmeyer. “Glutamine prevents apoptosis in intestinal epithelial cells and induces differential protective pathways in heat and oxidant injury models.” Jpen J Parenter Enteral Nutr 36, no. 5 (September 2012): 551–55. https://doi.org/10.1177/0148607112445579.Full Text Link to Item
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Sufit, Alexandra, Lindsay B. Weitzel, Christine Hamiel, Kelly Queensland, Ira Dauber, Olav Rooyackers, and Paul E. Wischmeyer. “Pharmacologically dosed oral glutamine reduces myocardial injury in patients undergoing cardiac surgery: a randomized pilot feasibility trial.” Jpen J Parenter Enteral Nutr 36, no. 5 (September 2012): 556–61. https://doi.org/10.1177/0148607112448823.Full Text Link to Item
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Niederlechner, Stefanie, Jelena Klawitter, Christine Baird, Alyssa Kallweit, Uwe Christians, and Paul Wischmeyer. “Fibronectin stabilization and Fibronectin-Integrin signaling via MAPK are required in L-Glutamine-mediated protection against gut injury.” Faseb Journal 26 (April 1, 2012).Link to Item
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Cheng, Sara S., Kristen Nordenholz, David Matero, Nathan Pearlman, Martin McCarter, Csaba Gajdos, Christine Hamiel, et al. “Standard subcutaneous dosing of unfractionated heparin for venous thromboembolism prophylaxis in surgical ICU patients leads to subtherapeutic factor Xa inhibition.” Intensive Care Med 38, no. 4 (April 2012): 642–48. https://doi.org/10.1007/s00134-011-2453-4.Full Text Link to Item
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Wischmeyer, Paul. “Parenteral nutrition and calorie delivery in the ICU: controversy, clarity, or call to action?” Curr Opin Crit Care 18, no. 2 (April 2012): 164–73. https://doi.org/10.1097/MCC.0b013e3283514be5.Full Text Link to Item
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Niederlechner, Stefanie, Jelena Klawitter, Christine Baird, Alyssa R. Kallweit, Uwe Christians, and Paul E. Wischmeyer. “Fibronectin-integrin signaling is required for L-glutamine's protection against gut injury.” Plos One 7, no. 11 (2012): e50185. https://doi.org/10.1371/journal.pone.0050185.Full Text Link to Item
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Turpin, Robin S., Todd Canada, Frank Xiaoqing Liu, Catherine J. Mercaldi, Alessandro Pontes-Arruda, and Paul Wischmeyer. “Nutrition therapy cost analysis in the US: pre-mixed multi-chamber bag vs compounded parenteral nutrition.” Appl Health Econ Health Policy 9, no. 5 (September 1, 2011): 281–92. https://doi.org/10.2165/11594980-000000000-00000.Full Text Link to Item
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Wischmeyer, Paul. “Nutritional pharmacology in surgery and critical care: 'you must unlearn what you have learned'.” Curr Opin Anaesthesiol 24, no. 4 (August 2011): 381–88. https://doi.org/10.1097/ACO.0b013e32834872b6.Full Text Link to Item
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Wischmeyer, Paul. “What's new in Shock, July 2011?” Shock 36, no. 1 (July 2011): 1–4. https://doi.org/10.1097/SHK.0b013e31821f7611.Full Text Link to Item
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Drover, John W., Rupinder Dhaliwal, Lindsay Weitzel, Paul E. Wischmeyer, Juan B. Ochoa, and Daren K. Heyland. “Perioperative use of arginine-supplemented diets: a systematic review of the evidence.” J Am Coll Surg 212, no. 3 (March 2011): 385-399.e1. https://doi.org/10.1016/j.jamcollsurg.2010.10.016.Full Text Link to Item
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Xue, Hongyu, Alexandra J. D. Sufit, and Paul E. Wischmeyer. “Glutamine therapy improves outcome of in vitro and in vivo experimental colitis models.” Jpen J Parenter Enteral Nutr 35, no. 2 (March 2011): 188–97. https://doi.org/10.1177/0148607110381407.Full Text Link to Item
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Higgins, D., K. Queensland, P. Wischmeyer, A. Sufit, and D. Heyland. “IMPACT OF VITAMIN D DEFICIENCY ON OUTCOME IN CRITICALLY ILL PATIENTS.” Journal of Investigative Medicine 59, no. 1 (January 1, 2011): 202–202.Link to Item
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Wischmeyer, P. E. “Malnutrition in the acutely ill patient: Is it more than just protein and energy?” South African Journal of Clinical Nutrition 24, no. 3 SUPPL. 1 (January 1, 2011): 1–7. https://doi.org/10.1080/16070658.2011.11734372.Full Text
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Hegazi, Refaat A., and Paul E. Wischmeyer. “Clinical review: Optimizing enteral nutrition for critically ill patients--a simple data-driven formula.” Crit Care 15, no. 6 (2011): 234. https://doi.org/10.1186/cc10430.Full Text Open Access Copy Link to Item
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Xue, Hongyu, Michael B. Sawyer, Paul E. Wischmeyer, and Vickie E. Baracos. “Nutrition modulation of gastrointestinal toxicity related to cancer chemotherapy: from preclinical findings to clinical strategy.” Jpen J Parenter Enteral Nutr 35, no. 1 (January 2011): 74–90. https://doi.org/10.1177/0148607110377338.Full Text Link to Item
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Weitzel, Lindsay-Rae B., Tim Byers, Jenna Allen, Christina Finlayson, Steve M. Helmke, John E. Hokanson, Stephen W. Hunsucker, et al. “Discovery and verification of protein differences between Er positive/Her2/neu negative breast tumor tissue and matched adjacent normal breast tissue.” Breast Cancer Res Treat 124, no. 2 (November 2010): 297–305. https://doi.org/10.1007/s10549-009-0721-6.Full Text Link to Item
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Wischmeyer, Paul E. “Pharmaconutrition and nutrition therapy in critical illness. Preface.” Crit Care Clin 26, no. 3 (July 2010): xiii–xiv. https://doi.org/10.1016/j.ccc.2010.05.001.Full Text Link to Item
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Weitzel, Lindsay-Rae B., and Paul E. Wischmeyer. “Glutamine in critical illness: the time has come, the time is now.” Crit Care Clin 26, no. 3 (July 2010): 515–x. https://doi.org/10.1016/j.ccc.2010.04.006.Full Text Link to Item
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Wischmeyer, Paul E., and Daren K. Heyland. “The future of critical care nutrition therapy.” Crit Care Clin 26, no. 3 (July 2010): 433–vii. https://doi.org/10.1016/j.ccc.2010.04.011.Full Text Link to Item
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Kuhn, Katharina S., Maurizio Muscaritoli, Paul Wischmeyer, and Peter Stehle. “Glutamine as indispensable nutrient in oncology: experimental and clinical evidence.” Eur J Nutr 49, no. 4 (June 2010): 197–210. https://doi.org/10.1007/s00394-009-0082-2.Full Text Link to Item
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Drover, John W., Naomi E. Cahill, Jim Kutsogiannis, Giuseppe Pagliarello, Paul Wischmeyer, Miao Wang, Andrew G. Day, and Daren K. Heyland. “Nutrition therapy for the critically ill surgical patient: we need to do better!.” Jpen J Parenter Enteral Nutr 34, no. 6 (2010): 644–52. https://doi.org/10.1177/0148607110372391.Full Text Link to Item
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Hamiel, Christine R., Shanti Pinto, Ann Hau, and Paul E. Wischmeyer. “Glutamine enhances heat shock protein 70 expression via increased hexosamine biosynthetic pathway activity.” Am J Physiol Cell Physiol 297, no. 6 (December 2009): C1509–19. https://doi.org/10.1152/ajpcell.00240.2009.Full Text Link to Item
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Weitzel, Lindsay-Rae B., Paul A. Sandoval, W Jonathan Mayles, and Paul E. Wischmeyer. “Performance-enhancing sports supplements: role in critical care.” Crit Care Med 37, no. 10 Suppl (October 2009): S400–409. https://doi.org/10.1097/CCM.0b013e3181b6f2e6.Full Text Link to Item
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Weitzel, Lindsay-Rae B., William J. Mayles, Paul A. Sandoval, and Paul E. Wischmeyer. “Effects of pharmaconutrients on cellular dysfunction and the microcirculation in critical illness.” Curr Opin Anaesthesiol 22, no. 2 (April 2009): 177–83. https://doi.org/10.1097/ACO.0b013e328328d32f.Full Text Link to Item
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Wischmeyer, Paul E. “Glutamine in acute lung injury: the experimental model matters.” Am J Physiol Lung Cell Mol Physiol 296, no. 3 (March 2009): L286–87. https://doi.org/10.1152/ajplung.00003.2009.Full Text Link to Item
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Arcaroli, John J., John E. Hokanson, Edward Abraham, Mark Geraci, James R. Murphy, Russell P. Bowler, Charles A. Dinarello, et al. “Extracellular superoxide dismutase haplotypes are associated with acute lung injury and mortality.” Am J Respir Crit Care Med 179, no. 2 (January 15, 2009): 105–12. https://doi.org/10.1164/rccm.200710-1566OC.Full Text Link to Item
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Ariefdjohan, M., K. Queensland, L. Weitzel, D. Heyland, and P. Wischmeyer. “ELEVATED ADMISSION IL-10 LEVEL IS ASSOCIATED WITH DEVEOPMENT OF SEPSIS IN CRITICALLY ILL ADULTS.” Shock 31 (January 1, 2009): 85–86.Link to Item
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Hamiel, C., A. Baer, E. Luzier, S. Cheng, and P. Wischmeyer. “GOAL-DIRECTED INTRAVENOUS HEPARIN, BUT NOT SUBCUTANEOUS HEPARIN, IMPROVES POST-SURGICAL HYPERCOAGULABLE STATE IN SICU PATIENTS.” Shock 31 (January 1, 2009): 36–36.Link to Item
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Weitzel, L., R. Dhaliwal, J. Drover, G. Haeussner, D. Heyland, and P. Wischmeyer. “SYSTEMATIC REVIEW OF PERI-OPERATIVE IMMUNE-MODULATING NUTRITION THERAPY: A NEW STANDARD OF CARE?” Shock 31 (January 1, 2009): 62–63.Link to Item
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McClave, Stephen A., Daren K. Heyland, and Paul E. Wischmeyer. “Comment on: probiotic prophylaxis in predicted severe acute pancreatitis: a randomized, double-blind, placebo-controlled trial.” Jpen J Parenter Enteral Nutr 33, no. 4 (2009): 444–46. https://doi.org/10.1177/0148607108331176.Full Text Link to Item
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Ganter, Michael T., Saskia Schmuck, Christine R. Hamiel, Paul E. Wischmeyer, Daniela Heule, Andreas Zollinger, and Christoph K. Hofer. “Monitoring recombinant factor VIIa treatment: efficacy depends on high levels of fibrinogen in a model of severe dilutional coagulopathy.” J Cardiothorac Vasc Anesth 22, no. 5 (October 2008): 675–80. https://doi.org/10.1053/j.jvca.2008.01.017.Full Text Link to Item
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Singleton, Kristen D., and Paul E. Wischmeyer. “Glutamine attenuates inflammation and NF-kappaB activation via Cullin-1 deneddylation.” Biochem Biophys Res Commun 373, no. 3 (August 29, 2008): 445–49. https://doi.org/10.1016/j.bbrc.2008.06.057.Full Text Link to Item
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Wischmeyer, Paul E. “Glutamine: role in critical illness and ongoing clinical trials.” Curr Opin Gastroenterol 24, no. 2 (March 2008): 190–97. https://doi.org/10.1097/MOG.0b013e3282f4db94.Full Text Link to Item
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Landzinski, James, Tyree H. Kiser, Douglas N. Fish, Paul E. Wischmeyer, and Robert MacLaren. “Gastric motility function in critically ill patients tolerant vs intolerant to gastric nutrition.” Jpen J Parenter Enteral Nutr 32, no. 1 (2008): 45–50. https://doi.org/10.1177/014860710803200145.Full Text Link to Item
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MacLaren, Robert, Tyree H. Kiser, Douglas N. Fish, and Paul E. Wischmeyer. “Erythromycin vs metoclopramide for facilitating gastric emptying and tolerance to intragastric nutrition in critically ill patients.” Jpen J Parenter Enteral Nutr 32, no. 4 (2008): 412–19. https://doi.org/10.1177/0148607108319803.Full Text Link to Item
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Singleton, Kristen D., and Paul E. Wischmeyer. “Glutamine induces heat shock protein expression via O-glycosylation and phosphorylation of HSF-1 and Sp1.” Jpen J Parenter Enteral Nutr 32, no. 4 (2008): 371–76. https://doi.org/10.1177/0148607108320661.Full Text Link to Item
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Skillman, Heather E., and Paul E. Wischmeyer. “Nutrition therapy in critically ill infants and children.” Jpen J Parenter Enteral Nutr 32, no. 5 (2008): 520–34. https://doi.org/10.1177/0148607108322398.Full Text Link to Item
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Wischmeyer, Paul E. “JPEN: State of the Journal.” Jpen J Parenter Enteral Nutr 32, no. 1 (2008): 101–3. https://doi.org/10.1177/0148607108032001101.Full Text Link to Item
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Wischmeyer, Paul. “Research and advocacy in nutrition therapy: our specialty needs you.” Jpen J Parenter Enteral Nutr 32, no. 2 (2008): 210–12. https://doi.org/10.1177/0148607108314767.Full Text Link to Item
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Wischmeyer, Paul E., Bradley R. Johnson, Joel E. Wilson, Colleen Dingmann, Heidi M. Bachman, Evan Roller, Zung Vu Tran, and Thomas K. Henthorn. “A survey of propofol abuse in academic anesthesia programs.” Anesth Analg 105, no. 4 (October 2007): 1066–71. https://doi.org/10.1213/01.ane.0000270215.86253.30.Full Text Link to Item
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Wischmeyer, Paul E. “Glutamine: mode of action in critical illness.” Crit Care Med 35, no. 9 Suppl (September 2007): S541–44. https://doi.org/10.1097/01.CCM.0000278064.32780.D3.Full Text Link to Item
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Singleton, Kristen D., and Paul E. Wischmeyer. “Glutamine's protection against sepsis and lung injury is dependent on heat shock protein 70 expression.” Am J Physiol Regul Integr Comp Physiol 292, no. 5 (May 2007): R1839–45. https://doi.org/10.1152/ajpregu.00755.2006.Full Text Link to Item
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Singleton, K. D., and P. E. Wischmeyer. “Reply to Eisenhut [2].” American Journal of Physiology Lung Cellular and Molecular Physiology 292, no. 1 (January 1, 2007). https://doi.org/10.1152/ajplung.00339.2006.Full Text
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Heyland, Daren K., Rupinder Dhaliwalm, Andrew Day, John Drover, Helene Cote, and Paul Wischmeyer. “Optimizing the dose of glutamine dipeptides and antioxidants in critically ill patients: a phase I dose-finding study.” Jpen J Parenter Enteral Nutr 31, no. 2 (2007): 109–18. https://doi.org/10.1177/0148607107031002109.Full Text Link to Item
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Wischmeyer, P. “Author's response.” Journal of Parenteral and Enteral Nutrition 30, no. 5 (December 1, 2006): 407.
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Friese, Randall S., and Paul Wischmeyer. “Glutamine attenuation of cell death and inducible nitric oxide synthase expression following inflammatory cytokine-induced injury is dependent on heat shock factor-1 expression - Discussant - Author's response.” Journal of Parenteral and Enteral Nutrition 30, no. 5 (September 1, 2006): 406–7.Link to Item
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Wischmeyer, Paul E. “Glutamine: role in gut protection in critical illness.” Curr Opin Clin Nutr Metab Care 9, no. 5 (September 2006): 607–12. https://doi.org/10.1097/01.mco.0000241672.09676.03.Full Text Link to Item
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Morrison, Angela L., Martin Dinges, Kristen D. Singleton, Kelli Odoms, Hector R. Wong, and Paul E. Wischmeyer. “Glutamine's protection against cellular injury is dependent on heat shock factor-1.” Am J Physiol Cell Physiol 290, no. 6 (June 2006): C1625–32. https://doi.org/10.1152/ajpcell.00635.2005.Full Text Link to Item
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Singleton, Kristen D., and Paul E. Wischmeyer. “Effects of HSP70.1/3 gene knockout on acute respiratory distress syndrome and the inflammatory response following sepsis.” Am J Physiol Lung Cell Mol Physiol 290, no. 5 (May 2006): L956–61. https://doi.org/10.1152/ajplung.00466.2005.Full Text Link to Item
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Wischmeyer, Paul E. “Glutamine: the first clinically relevant pharmacological regulator of heat shock protein expression?” Curr Opin Clin Nutr Metab Care 9, no. 3 (May 2006): 201–6. https://doi.org/10.1097/01.mco.0000222100.44256.6b.Full Text Link to Item
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Wischmeyer, Paul E. “The glutamine story: where are we now?” Curr Opin Crit Care 12, no. 2 (April 2006): 142–48. https://doi.org/10.1097/01.ccx.0000216582.87674.a4.Full Text Link to Item
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Singleton, Kristen D., and Paul E. Wischmeyer. “Oral glutamine enhances heat shock protein expression and improves survival following hyperthermia.” Shock 25, no. 3 (March 2006): 295–99. https://doi.org/10.1097/01.shk.0000196548.10634.02.Full Text Link to Item
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Peng, Zhi Yong, Natalie J. Serkova, Douglas J. Kominsky, Jaimi L. Brown, and Paul E. Wischmeyer. “Glutamine-mediated attenuation of cellular metabolic dysfunction and cell death after injury is dependent on heat shock factor-1 expression.” Jpen J Parenter Enteral Nutr 30, no. 5 (2006): 373–78. https://doi.org/10.1177/0148607106030005373.Full Text Link to Item
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Peng, Zhi-Yong, Christine R. Hamiel, Anirban Banerjee, Paul E. Wischmeyer, Randall S. Friese, and Paul Wischmeyer. “Glutamine attenuation of cell death and inducible nitric oxide synthase expression following inflammatory cytokine-induced injury is dependent on heat shock factor-1 expression.” Jpen J Parenter Enteral Nutr 30, no. 5 (2006): 400–406. https://doi.org/10.1177/0148607106030005400.Full Text Link to Item
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Singleton, K. D., V. E. Beckey, and P. E. Wischmeyer. “GLUTAMINE PREVENTS ACTIVATION OF NF-kappaB AND STRESS KINASE PATHWAYS, ATTENUATES INFLAMMATORY CYTOKINE RELEASE, AND PREVENTS ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) FOLLOWING SEPSIS.” Shock (Augusta, Ga.) 24, no. 6 (December 1, 2005): 583–89.
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Singleton, Kristen D., Virginia E. Beckey, and Paul E. Wischmeyer. “GLUTAMINE PREVENTS ACTIVATION OF NF-kappaB AND STRESS KINASE PATHWAYS, ATTENUATES INFLAMMATORY CYTOKINE RELEASE, AND PREVENTS ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) FOLLOWING SEPSIS.” Shock 24, no. 6 (December 2005): 583–89. https://doi.org/10.1097/01.shk.0000185795.96964.71.Full Text Link to Item
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Ziegler, Thomas R., Lorraine G. Ogden, Kristen D. Singleton, Menghua Luo, Concepcion Fernandez-Estivariz, Daniel P. Griffith, John R. Galloway, and Paul E. Wischmeyer. “Parenteral glutamine increases serum heat shock protein 70 in critically ill patients.” Intensive Care Med 31, no. 8 (August 2005): 1079–86. https://doi.org/10.1007/s00134-005-2690-5.Full Text Link to Item
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Singleton, Kristen D., Natalie Serkova, Virgina E. Beckey, and Paul E. Wischmeyer. “Glutamine attenuates lung injury and improves survival after sepsis: role of enhanced heat shock protein expression.” Crit Care Med 33, no. 6 (June 2005): 1206–13. https://doi.org/10.1097/01.ccm.0000166357.10996.8a.Full Text Link to Item
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Wischmeyer, Paul E. “Can glutamine turn off the motor that drives systemic inflammation?” Crit Care Med 33, no. 5 (May 2005): 1175–78. https://doi.org/10.1097/01.ccm.0000162686.28604.81.Full Text Link to Item
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Singleton, Kristen D., Natalie Serkova, Anirban Banerjee, Xianzhong Meng, Fabia Gamboni-Robertson, and Paul E. Wischmeyer. “Glutamine attenuates endotoxin-induced lung metabolic dysfunction: potential role of enhanced heat shock protein 70.” Nutrition 21, no. 2 (February 2005): 214–23. https://doi.org/10.1016/j.nut.2004.05.023.Full Text Link to Item
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Wischmeyer, Paul. “John M. Kinney International Award for General Nutrition. Glutamine, heat shock protein, and inflammation--opportunity from the midst of difficulty.” Nutrition 20, no. 6 (June 2004): 583–85. https://doi.org/10.1016/j.nut.2004.03.006.Full Text Link to Item
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Wischmeyer, P. “Glutamine, heat shock protein, and inflammation - Opportunity from the midst of difficulty.” South African Journal of Clinical Nutrition 17, no. 3 (January 1, 2004): 84–86. https://doi.org/10.1080/16070658.2004.11734024.Full Text
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Savarese, Diane M. F., Gayle Savy, Linda Vahdat, Paul E. Wischmeyer, and Barbara Corey. “Prevention of chemotherapy and radiation toxicity with glutamine.” Cancer Treat Rev 29, no. 6 (December 2003): 501–13. https://doi.org/10.1016/s0305-7372(03)00133-6.Full Text Link to Item
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Wischmeyer, Paul E. “Clinical applications of L-glutamine: past, present, and future.” Nutr Clin Pract 18, no. 5 (October 2003): 377–85. https://doi.org/10.1177/0115426503018005377.Full Text Link to Item
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Kelly, David, and Paul E. Wischmeyer. “Role of L-glutamine in critical illness: new insights.” Curr Opin Clin Nutr Metab Care 6, no. 2 (March 2003): 217–22. https://doi.org/10.1097/00075197-200303000-00011.Full Text Link to Item
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Singleton, K. D., and P. E. Wischmeyer. “Distance of cecum ligated influences mortality, tumor necrosis factor-alpha and interleukin-6 expression following cecal ligation and puncture in the rat.” Eur Surg Res 35, no. 6 (2003): 486–91. https://doi.org/10.1159/000073387.Full Text Link to Item
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Wischmeyer, Paul E., David Jayakar, Ursula Williams, Kristen D. Singleton, Jacob Riehm, Emile A. Bacha, Valluvan Jeevanandam, Uwe Christians, and Natalie Serkova. “Single dose of glutamine enhances myocardial tissue metabolism, glutathione content, and improves myocardial function after ischemia-reperfusion injury.” Jpen J Parenter Enteral Nutr 27, no. 6 (2003): 396–403. https://doi.org/10.1177/0148607103027006396.Full Text Link to Item
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Wischmeyer, Paul E., Jacob Riehm, Kristen D. Singleton, Hongyu Ren, Mark W. Musch, Madelyn Kahana, and Eugene B. Chang. “Glutamine attenuates tumor necrosis factor-alpha release and enhances heat shock protein 72 in human peripheral blood mononuclear cells.” Nutrition 19, no. 1 (January 2003): 1–6. https://doi.org/10.1016/s0899-9007(02)00839-0.Full Text Link to Item
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Wischmeyer, Paul E., Terry L. Vanden Hoek, Changquiung Li, Zuohui Shao, Hongyu Ren, Jacob Riehm, and Lance B. Becker. “Glutamine preserves cardiomyocyte viability and enhances recovery of contractile function after ischemia-reperfusion injury.” Jpen J Parenter Enteral Nutr 27, no. 2 (2003): 116–22. https://doi.org/10.1177/0148607103027002116.Full Text Link to Item
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Wischmeyer, P. “Intravenous glutamine administration after major burn injury: Nutrition or pharmacology?” International Journal of Intensive Care 9, no. 4 (December 1, 2002): 188–94.
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Wischmeyer, Paul E. “Glutamine and heat shock protein expression.” Nutrition 18, no. 3 (March 2002): 225–28. https://doi.org/10.1016/s0899-9007(01)00796-1.Full Text Link to Item
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Liedel, J. L., M. D. Kahana, T. Krausz, H. Y. Ren, M. W. Musch, P. Wischmeyer, R. Wolfson, and E. B. Chang. “Intermittent isoflurane does not attenuate hyperoxic lung injury in the rat.” Critical Care Medicine 29, no. 12 (December 1, 2001): A152–A152.Link to Item
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Wischmeyer, P. E., D. Jayakar, U. Williams, E. A. Bacha, V. Jeevanandum, and M. Kahana. “Glutamine pre-conditioning enhances recovery of cardiac function following ischemia/reperfusion injury in the rat.” Critical Care Medicine 29, no. 12 (December 1, 2001): A104–A104.Link to Item
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Wischmeyer, P. E., J. Lynch, J. Liedel, R. Wolfson, J. Riehm, L. Gottlieb, and M. Kahana. “Glutamine administration reduces Gram-negative bacteremia in severely burned patients: a prospective, randomized, double-blind trial versus isonitrogenous control.” Crit Care Med 29, no. 11 (November 2001): 2075–80. https://doi.org/10.1097/00003246-200111000-00006.Full Text Link to Item
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Wischmeyer, P. E., M. Kahana, R. Wolfson, H. Ren, M. M. Musch, and E. B. Chang. “Glutamine reduces cytokine release, organ damage, and mortality in a rat model of endotoxemia.” Shock 16, no. 5 (November 2001): 398–402. https://doi.org/10.1097/00024382-200116050-00014.Full Text Link to Item
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Wischmeyer, P. E., M. Kahana, R. Wolfson, H. Ren, M. M. Musch, and E. B. Chang. “Glutamine induces heat shock protein and protects against endotoxin shock in the rat.” J Appl Physiol (1985) 90, no. 6 (June 2001): 2403–10. https://doi.org/10.1152/jappl.2001.90.6.2403.Full Text Link to Item
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Wischmeyer, P. E., J. L. Liedel, R. K. Wolfson, J. Lynch, J. Riehm, L. Gottlieb, and M. D. Kahana. “Glutamine administration reduces gram negative: Bacteremia in severely burned patients.” Critical Care Medicine 28, no. 12 (December 1, 2000): A148–A148.Link to Item
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Wischmeyer, P. E., M. D. Kahana, T. L. Vanden Hoek, C. Q. Li, Z. H. Shao, J. L. Liedel, J. Riehm, and L. B. Becker. “Glutamine reduces cell death and induces recovery of contractile function in cardiac myocytes after ischemia/reperfusion injury.” Critical Care Medicine 28, no. 12 (December 1, 2000): A33–A33.Link to Item
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Conran, A., P. Wischmeyer, R. Wolfson, M. Musch, and M. Kahana. “Alpha-2-agonists (A2As) increases anesthetic mortality in a rat model of endotoxemia.” Anesthesiology 93, no. 3A (September 1, 2000): U161–U161.Link to Item
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Musch, Mark W., Paul Wischmeyer, Hongyu Ren, Madelyn Kahana, and Eugene B. Chang. “Glutamine infusion induces heat shock proteins 25 and 72 in rat colon, lung, and heart: Potential role as a cytoprotective therapeutic agent.” Gastroenterology 118, no. 4 (April 2000): A75–A75. https://doi.org/10.1016/s0016-5085(00)82375-6.Full Text
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Wischmeyer, P. E., M. Musch, M. Kahana, E. Chang, and M. Roizen. “Heat shock protein induction in heart and lung tissue after glutamine infusion.” Anesthesia and Analgesia 90, no. 2 (February 1, 2000): U98–U98.Link to Item
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Wischmeyer, P. E., M. W. Musch, M. B. Madonna, R. Thisted, and E. B. Chang. “Glutamine protects intestinal epithelial cells: role of inducible HSP70.” Am J Physiol 272, no. 4 Pt 1 (April 1997): G879–84. https://doi.org/10.1152/ajpgi.1997.272.4.G879.Full Text Link to Item
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Wischmeyer, P. E., M. W. Musch, M. B. Madonna, R. Thisted, and E. B. Chang. “Glutamine protects intestinal epithelial cells: Role of inducible HSP70.” American Journal of Physiology Gastrointestinal and Liver Physiology 272, no. 4 (April 1, 1997): G879–84.Link to Item
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WISCHMEYER, P., M. W. MUSCH, R. THISTED, G. BURRESS, and E. B. CHANG. “GLUTAMINE CYTOPROTECTS INTESTINAL EPITHELIAL-CELLS VIA HEAT-SHOCK PROTEIN INDUCTION.” Gastroenterology 108, no. 4 (April 1, 1995): A943–A943.Link to Item
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WISCHMEYER, P., M. W. MUSCH, D. JURIVITCH, and E. B. CHANG. “GLUTAMINE CYTOPROTECTS VIA HEAT-SHOCK PROTEIN INDUCTION IN INTESTINAL EPITHELIAL-CELLS.” Gastroenterology 106, no. 4 (April 1, 1994): A1055–A1055.Link to Item
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Wischmeyer, P., J. H. Pemberton, and S. F. Phillips. “Chronic pouchitis after ileal pouch-anal anastomosis: responses to butyrate and glutamine suppositories in a pilot study.” Mayo Clin Proc 68, no. 10 (October 1993): 978–81. https://doi.org/10.1016/s0025-6196(12)62270-8.Full Text Link to Item
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Book Sections
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Xue, H., and P. Wischmeyer. “Therapeutic role of glutamine in inflammatory bowel disease.” In Glutamine: Biochemistry, Physiology, and Clinical Applications, 165–82, 2017. https://doi.org/10.1201/9781315373164.Full Text
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Kim, Mike, and Paul E. Wischmeyer. “Glutamine.,” 105:90–96, 2013. https://doi.org/10.1159/000341276.Full Text Link to Item
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Wischmeyer, P. E. “Preface,” Vol. 26, 2010. https://doi.org/10.1016/j.ccc.2010.05.001.Full Text
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Journal Issues
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Munger, M. C., and M. Hinich. “Editors' Introduction.” Public Choice: Empirical Studies in Comparative Politics. Springer Verlag (Germany), 1998.
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Conference Papers
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Haines, Krista L., Charles N. Trujillo, Tetsu Ohnuma, Vijay Krishnamoorthy, Karthik Raghunathan, Suela Sulo, Kirk W. Kerr, Beth Besecker, Bridget Cassady, and Paul E. Wischmeyer. “Early Enteral Nutrition Improves Outcomes in Critically Ill Mechanically Ventilated Patients.” In Anesthesia and Analgesia, 134:305–6, 2022.Link to Item
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Haines, Krista, Tetsu Ohnuma, Vijay Krishnamoorthy, Karthik Raghunathan, and Paul Wischmeyer. “HOSPITAL CHANGE TO SMOF LIPID PARENTERAL NUTRITION IN CRITICALLY ILL ADULTS IMPROVES OUTCOMES.” In Critical Care Medicine, 50:282–282, 2022.Link to Item
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Wischmeyer, Paul, Tetsu Ohnuma, Vijay Krishnamoorthy, Karthik Raghunathan, and Krista Haines. “HOSPITAL CHANGE TO SMOF LIPID PARENTERAL NUTRITION IN THE PEDIATRIC ICU IMPROVES CLINICAL OUTCOMES.” In Critical Care Medicine, 50:298–298, 2022.Link to Item
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Obanor, Osamudiamen, Krista L. Haines, Vijay Krishnamoorthy, David G. Williams, Karthik Raghunathan, Tetsu Ohnuma, and Paul E. Wischmeyer. “Initiation of SMOFLipid in Single Health System affects Hospital Length of Stay among Critically Ill Adults Requiring Total Parenteral Nutrition.” In Anesthesia and Analgesia, 132:212–13, 2021.Link to Item
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Lao, William Shihao, Krista L. Haines, Scott Gallagher, Suresh Agarwal, Paul E. Wischmeyer, and Vijay Krishnamoorthy. “GLIM Directed Malnutrition Predicts Morbidity and Mortality Following Emergent GI Surgery.” In Anesthesia and Analgesia, 130:215–215, 2020.Link to Item
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Lao, William, Krista Haines, David Anderson, Scott Gallagher, Suresh Agarwal, and Paul Wischmeyer. “GLIM-DIRECTED MALNUTRITION PREDICTS MORBIDITY AND MORTALITY AFTER EMERGENT GASTROINTESTINAL SURGERY.” In Critical Care Medicine, Vol. 48, 2020.Link to Item
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Williams, D. G., T. Ohnuma, V. Krishnamoorthy, K. Raghunathan, S. Sulo, B. A. Cassady, R. Hegazi, and P. E. Wischmeyer. “ORAL NUTRITIONAL SUPPLEMENTATION CAN IMPROVE POSTOPERATIVE OUTCOMES FOR COLORECTAL SURGERY PATIENTS.” In Value in Health, 23:S10–S10, 2020.Link to Item
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Williams, David G., Tetsu Ohnuma, Vijay Krishnamoorthy, Karthik Raghunathan, Suela Sulo, Bridget Cassady, Refaat Hegazi, and Paul E. Wischmeyer. “Utilization of Oral Nutritional Supplements in Postoperative Hospitalized US Surgical Patients.” In Anesthesia and Analgesia, 130:829–829, 2020.Link to Item
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Wischmeyer, Paul, Yaozhu J. Chen, Jen Judy, Dorothy Baumer, Scott B. Robinson, George Dukes, Cristina Almansa, David Liska, and Conor P. Delaney. “IMPACT OF POST-OPERATIVE ILEUS AMONG INPATIENTS UNDERGOING GASTROINTESTINAL SURGERIES IN THE UNITED STATES.” In Gastroenterology, 158:S1553–S1553, 2020.Link to Item
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Lew, Meagan V., Yi Ren, Yen P. Lowder, Kristi M. Romero, Jillian C. Thompson, Lauren M. Bohannon, Harvey Cohen, et al. “Geriatric Assessment Identifies Impairments in Younger Candidates for Allogeneic Hematopoietic Stem Cell Transplantation.” In Blood, 134:1984–1984. American Society of Hematology, 2019. https://doi.org/10.1182/blood-2019-127264.Full Text
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Paul, M., D. Lanctin, J. Partridge, D. G. Williams, and P. E. Wischmeyer. “PAM8 IMPACT OF PERIOPERATIVE NUTRITION ON HEALTH OUTCOMES IN ONCOLOGY PATIENTS UNDERGOING GASTROINTESTINAL SURGERIES.” In Value in Health, 22:S45–S45. Elsevier BV, 2019. https://doi.org/10.1016/j.jval.2019.04.072.Full Text
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Wang, Yingqi, Andrew Chang, Wei Phin Tan, Joseph Fantony, Gregory Barton, Paul Wischmeyer, Rajan Gupta, and Brant Inman. “INCREASING ADIPOSITY IN BLADDER CANCER SURVIVORS: DOES DIET MATTER?” In Journal of Urology, 201:E47–E47. LIPPINCOTT WILLIAMS & WILKINS, 2019.Link to Item
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Barton, Gregory John, Jeanette Wang, Andrew Chang, Wei Phin Tan, Joseph J. Fantony, Paul E. Wischmeyer, Rajan T. Gupta, and Brant Allen Inman. “Sarcopenia in bladder cancer patients is an unmodifiable outcomes predictor.” In Journal of Clinical Oncology, 37:480–480. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.7_suppl.480.Full Text
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Fleming, Jenna K., Carine M. Renner, Christine H. Baird, Jon Henderson, Paul E. Wischmeyer, and Jesse Davidson. “ALKALINE PHOSPHATASE ALTERS CLOT INITIATION, AMPLIFICATION, AND PROPAGATION IN HEALTHY HUMAN ADULT DONORS.” In Shock, 47:110–110. LIPPINCOTT WILLIAMS & WILKINS, 2017.Link to Item
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Renner, Carine M., Jenna K. Fleming, Christine H. Baird, Jon Henderson, and Paul E. Wischmeyer. “SONOCLOT ANALYSIS MEASURES INITIAL HYPER-COAGULABLE STATE IN TRAUMATIC BRAIN INJURY.” In Shock, 47:110–11. LIPPINCOTT WILLIAMS & WILKINS, 2017.Link to Item
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Gorman, K., D. McDonald, and P. Wischmeyer. “QUANTIFYING ANTIBIOTIC PRESSURE SCORES TO DETERMINE IMPACT ON ORAL AND FECAL MICROBIOME IN CRITICALLY ILL PATIENTS.” In Journal of Investigative Medicine, 65:278–278. BMJ PUBLISHING GROUP, 2017. https://doi.org/10.1136/jim-2016-000365.423.Full Text Link to Item
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Barnes, C., C. H. Baird, C. Pisani, J. Henderson, and P. Wischmeyer. “SONOCLOT CAN SIMULTANEOUSLY MONITOR GLYCOPROTEIN IIB/IIIA-MEDIATED PLATELET INHIBITION, ACTIVATED CLOTTING TIME AND CLOT RATE RESULTS.” In Shock, 45:87–88. LIPPINCOTT WILLIAMS & WILKINS, 2016.Link to Item
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Wischmeyer, P., C. H. Baird, M. Jeschke, O. Rooijackers, and D. Heyland. “A MULTI-CENTER RANDOMIZED TRIAL OF ENTERAL GLUTAMINE IN BURN PATIENTS: RE-ENERGIZE PILOT TRIAL RESULTS.” In Shock, 45:44–45. LIPPINCOTT WILLIAMS & WILKINS, 2016.Link to Item
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Wischmeyer, P., D. Mcdonald, C. H. Baird, D. Heyland, and R. Knight. “THE ICU MICROBIOME PROJECT: CRITICAL ILLNESS ASSOCIATES WITH LOSS OF MICROBIAL DIVERSITY AND ALTERATIONS IN METAGENOMICS.” In Shock, 45:16–17. LIPPINCOTT WILLIAMS & WILKINS, 2016.Link to Item
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Wischmeyer, P., R. Kozar, R. Dhaliwal, X. Jiang, A. Day, and D. Heyland. “THE TOP-UP PILOT TRIAL: A RANDOMIZED TRIAL OF SUPPLEMENTAL PARENTERAL NUTRITION IN UNDER AND OVER WEIGHT ICU PATIENTS.” In Shock, 45:71–72. LIPPINCOTT WILLIAMS & WILKINS, 2016.Link to Item
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Davidson, Jesse, Tracy Urban, Suhong Tong, Christine Baird, Ludmila Khailova, James Jaggers, and Paul Wischmeyer. “ALKALINE PHOSPHATASE ACTIVITY PREDICTS ORGAN INJURY AND DYSFUNCTION AFTER INFANT CARDIAC SURGERY.” In Critical Care Medicine, Vol. 43. LIPPINCOTT WILLIAMS & WILKINS, 2015.Link to Item
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Heyland, Daren, Paul Wischmeyer, Lucy Wibbenmeyer, Bruce Friedman, Jonathan Pollack, Nathan Kemalyan, Marc Jeschke, and Dominique Garrel. “A RANDOMIZED TRIAL OF ENTERAL GLUTAMINE IN BURN PATIENTS: RESULTS OF A MULTICENTER PILOT STUDY.” In Critical Care Medicine, Vol. 43. LIPPINCOTT WILLIAMS & WILKINS, 2015.Link to Item
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Roller, Lauren, Robert MacLaren, Tyree Kiser, Scott Mueller, Douglas Fish, and Paul Wischmeyer. “The influence of acid suppressants on oral and fecal microbiomes in critically ill patients.” In Pharmacotherapy, 35:E265–E265. WILEY-BLACKWELL, 2015.Link to Item
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Baird, C. H., L. Khailova, and P. Wischmeyer. “LACTOBACILLUS RHAMNOSUS GG TREATMENT INCREASES COLONIC RETINALDEHYDE DEHYDROGENASE 2 LEVELS IN MURINE PSEUDOMONAS AERUGINOSA INDUCED PNEUMONIA.” In Shock, 43:85–85. LIPPINCOTT WILLIAMS & WILKINS, 2015.Link to Item
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Barnes, C., L. Khailova, C. H. Baird, and P. Wischmeyer. “TLR/COX-2 PATHWAYS ARE INVOLVED IN PROTECTIVE EFFECT OF LACTOBACILLUS RHAMNOSUS GG TREATMENT IN EXPERIMENTAL MODEL OF PSEUDOMONAS AERUGINOSA INDUCED PNEUMONIA.” In Shock, 43:119–20. LIPPINCOTT WILLIAMS & WILKINS, 2015.Link to Item
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Khailova, L., C. H. Baird, A. Fletcher, C. Evans, and P. Wischmeyer. “MUC5B EXPRESSION IS VITAL TO LACTOBACILLUS GG-MEDIATED SURVIVAL FOLLOWING EXPERIMENTAL PSEUDOMONAS AERUGINOSA PNEUMONIA.” In Shock, 43:118–118. LIPPINCOTT WILLIAMS & WILKINS, 2015.Link to Item
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Khailova, L., C. H. Baird, and P. Wischmeyer. “PROBIOTIC TREATMENT IN EXPERIMENTAL MODEL OF PSEUDOMONAS AERUGINOSA INDUCED PNEUMONIA: DOES GENDER PLAY A ROLE?” In Shock, 43:120–120. LIPPINCOTT WILLIAMS & WILKINS, 2015.Link to Item
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McDonald, D., G. Ackerman, L. Khailova, C. H. Baird, R. Knight, and P. Wischmeyer. “CHARACTERIZATION OF MICROBIOME IN CRITICALLY ILL PATIENTS AND RELATIONSHIP TO CLINICAL OUTCOME: THE ICU MICROBIOME MULTI-CENTER TRIAL PROJECT.” In Shock, 43:17–17. LIPPINCOTT WILLIAMS & WILKINS, 2015.Link to Item
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Snider, Julia Thornton, Anupam B. Jena, Mark T. Linthicum, Refaat A. Hegazi, Jamie S. Partridge, Chris LaVallee, Darius N. Lakdawalla, and Paul E. Wischmeyer. “Effect of hospital use of oral nutritional supplementation on length of stay, hospital cost, and 30-day readmissions among Medicare patients with COPD.” In Chest, 147:1477–84, 2015. https://doi.org/10.1378/chest.14-1368.Full Text Link to Item
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Baird, C. H., L. Khailova, and P. Wischmeyer. “LACTOBACILLUS RHAMNOSUS GG AND L-THREONINE TREATMENT ENHANCES MUC-2 MRNA EXPRESSION AND INCREASES CELL SURVIVAL IN HEAT STRESSED INTESTINAL EPITHELIAL CELLS.” In Shock, 41:81–82. LIPPINCOTT WILLIAMS & WILKINS, 2014.Link to Item
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Khailova, L., C. H. Baird, and P. Wischmeyer. “LACTOBACILLUS RHAMNOSUS LGG TREATMENT IMPROVES INTESTINAL PERMEABILITY IN EXPERIMENTAL PSEUDOMONAS AERUGINOSA INDUCED PNEUMONIA: ROLE OF MUCINS AND CLAUDIN-2.” In Shock, 41:98–98. LIPPINCOTT WILLIAMS & WILKINS, 2014.Link to Item
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Rush, A., L. Khailova, C. H. Baird, and P. Wischmeyer. “LACTOBACILLUS RHAMNOSUS GG IMPROVES HOMEOSTASIS IN THE COLON AND SPLEEN OF MICE WITH PSEUDOMONAS AERUGINOSA INDUCED PNEUMONIA.” In Shock, 41:86–86. LIPPINCOTT WILLIAMS & WILKINS, 2014.Link to Item
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Cheng, S., C. H. Baird, A. Almagro, E. Luzier, N. Pearlman, C. Gajdos, M. McCarter, et al. “PERIOPERATIVE VISCOELASTIC COAGULATION TESTING AS A PREDICTOR OF POST-DISCHARGE VTE AFTER MAJOR SURGERY.” In Shock, 39:93–93. LIPPINCOTT WILLIAMS & WILKINS, 2013.Link to Item
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Khailova, L., C. H. Baird, and P. E. Wischmeyer. “PROBIOTICS IMPROVE THE OUTCOME IN EXPERIMENTAL PSEUDOMONAS AERUGINOSA INDUCED PNEUMONIA: ROLE OF REGULATORY T CELLS.” In Shock, 39:15–16. LIPPINCOTT WILLIAMS & WILKINS, 2013.Link to Item
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Niederlechner, S., C. Aherne, A. Riegel, H. Eltzschig, and P. E. Wischmeyer. “GLUTAMINE IS PROTECTIVE IN THE INTESTINE VIA DIFFERENT PROTECTIVE PATHWAYS IN HEAT AND OXIDANT INJURY MODELS: ROLE OF NETRIN-1.” In Shock, 39:43–43. LIPPINCOTT WILLIAMS & WILKINS, 2013.Link to Item
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Van Swol, J. L., C. H. Baird, A. Kallweit, L. Khailova, and P. E. Wischmeyer. “GLUTAMINE TREATMENT INCREASES CLAUDIN-3 EXPRESSION AND NUCLEAR LOCALIZATION OF OCCLUDIN IN HEAT STRESSED INTESTINAL EPITHELIAL CELLS.” In Shock, 39:91–91. LIPPINCOTT WILLIAMS & WILKINS, 2013.Link to Item
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Winkler, Z., and P. Wischmeyer. “IDENTIFICATION OF A NOVEL PREDICTOR OF ANABOLIC/CATABOLIC BALANCE AND NUTRITIONAL STATUS IN CRITICAL ILLNESS: WHAT CAN BE LEARNED FROM ELITE ATHLETES?” In Journal of Investigative Medicine, 61:144–144. LIPPINCOTT WILLIAMS & WILKINS, 2013.Link to Item
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Niederlechner, Stefanie, Benjamin Petrie, and Paul Wischmeyer. “EPIDERMAL GROWTH FACTOR RECEPTOR EXPRESSION AND SIGNALING IS ESSENTIAL IN L-GLUTAMINE'S CYTOPROTECTIVE MECHANISM IN HEAT-STRESSED INTESTINAL EPITHELIAL-6 CELLS.” In Critical Care Medicine, 40:U95–U95. LIPPINCOTT WILLIAMS & WILKINS, 2012.Link to Item
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Xue, Hongyu, Dobromir Slavov, and Paul E. Wischmeyer. “Glutamine-mediated dual regulation of heat shock transcription factor-1 activation and expression.” In J Biol Chem, 287:40400–413, 2012. https://doi.org/10.1074/jbc.M112.410712.Full Text Link to Item
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Baird, Christine Hamiel, Alyssa Rene Kallweit, Ryan Beck, Stefanie Niederlechner, and Paul Edmund Wischmeyer. “Threonine treatment increases heat shock protein 25 and 70 expression and decreases apoptosis in heat stressed intestinal epithelial cells.” In Faseb Journal, Vol. 26. FEDERATION AMER SOC EXP BIOL, 2012.Link to Item
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Khailova, Ludmila, Paul Wischmeyer, and Jessica A. Dominguez. “Lactobacillus rhamnosus GG (LGG) and Bifidobacterium longum (BL) attenuate cytokine expression in the lungs of weanling mice with peritonitis-induced sepsis.” In Faseb Journal, Vol. 26. FEDERATION AMER SOC EXP BIOL, 2012.Link to Item
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Xue, Hongyu, Dobromir Slavov, and Paul Wischmeyer. “Glutamine activates heat shock transcription factor-1 (HSF1) gene transcription.” In Faseb Journal, Vol. 26. FEDERATION AMER SOC EXP BIOL, 2012.Link to Item
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Baird, C., A. Kallweit, S. Niederlechner, and P. E. Wischmeyer. “THREONINE TREATMENT DECREASES APOPTOSIS AND PHORPHORYLATION OF P38 MITOGEN ACTIVATED PROTEIN KINASE IN HEAT STRESSED INTESTINAL EPITHELIAL CELLS.” In Shock, 37:71–71. LIPPINCOTT WILLIAMS & WILKINS, 2012.Link to Item
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Khailova, L., P. Wischmeyer, and J. Dominguez. “LACTOBACILLUS RHAMNOSUS GG AND BIFIDOBACTERIUM LONGUM ATTENUATE INFLAMMATORY RESPONSE IN WEANLING MOUSE MODEL OF SEPTIC PERITONITIS.” In Shock, 37:79–79. LIPPINCOTT WILLIAMS & WILKINS, 2012.Link to Item
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Niederlechner, S., C. Aherne, A. Riegel, A. Kallweit, H. Eltzschig, and P. E. Wischmeyer. “NETRIN-1: NOVEL SURVIVAL FACTOR IN L-GLUTAMINE'S PROTECTIVE MECHANISM IN INTESTINAL EPITHELIAL CELLS.” In Shock, 37:92–93. LIPPINCOTT WILLIAMS & WILKINS, 2012.Link to Item
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Stutzman, D. K., C. Baird, A. Kallweit, L. Khailova, and P. E. Wischmeyer. “OSMOTICALLY ACTING AMINO ACIDS INDUCE HEAT SHOCK PROTEINS AND PROTECT INTESTINAL EPITHELIAL CELLS FROM LETHAL HEAT STRESS.” In Shock, 37:91–92. LIPPINCOTT WILLIAMS & WILKINS, 2012.Link to Item
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Xue, H., D. Slavov, and P. E. Wischmeyer. “DUAL REGULATION OF HEAT SHOCK TRANSCRIPTION FACTOR-1 (HSF1) TRANSACTIVATION ACTIVITY AND EXPRESSION BY GLUTAMINE.” In Shock, 37:93–93. LIPPINCOTT WILLIAMS & WILKINS, 2012.Link to Item
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Baird, C. H., A. R. Kallweit, S. Niederlechner, and P. E. Wischmeyer. “GLUTAMINE POST-TRANSLATIONALLY REGULATES INTRACELLULAR NUCLEAR FACTOR (ERYTHROID-DERIVED 2)-LIKE 2 PROTEIN LEVELS IN INTESTINAL EPITHELIAL CELLS.” In Shock, 35:71–71. LIPPINCOTT WILLIAMS & WILKINS, 2011.Link to Item
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Higgins, D., P. E. Wischmeyer, K. M. Queensland, S. H. Sillaun, A. J. Sufit, and D. K. Heyland. “RELATIONSHIP OF VITAMIN D DEFICIENCY TO CLINICAL OUTCOMES IN CRITICALLY ILL PATIENTS.” In Shock, 35:2–3. LIPPINCOTT WILLIAMS & WILKINS, 2011.Link to Item
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Kallweit, A. R., C. H. Baird, S. E. Niederlechner, and P. E. Wischmeyer. “GLUTAMINE PROTECTS INTESTINAL EPITHELIAL CELLS VIA DIFFERENT MOLECULAR MECHANISMS IN HEAT VS. OXIDANT STRESS.” In Shock, 35:9–9. LIPPINCOTT WILLIAMS & WILKINS, 2011.Link to Item
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Niederlechner, S., C. Baird, A. Kallweit, and P. Wischmeyer. “THE INVOLVEMENT OF INTEGRINS, SRC, AND EPIDERMAL GROWTH FACTOR RECEPTORS IN L-GLUTAMINE'S PROTECTIVE MECHANISM.” In Shock, 35:72–72. LIPPINCOTT WILLIAMS & WILKINS, 2011.Link to Item
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Xue, H., and P. E. Wischmeyer. “TRANSCRIPTIONAL REGULATION OF HEAT SHOCK TRANSCRIPTION FACTOR-1 (HSF1) BY GLUTAMINE.” In Shock, 35:43–43. LIPPINCOTT WILLIAMS & WILKINS, 2011.Link to Item
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Hamiel, Christine, Alyssa Kallweit, Alexandra Sufit, Lauren Zager, and Paul Wischmeyer. “GLUTAMINE TREATMENT INCREASES HEME OXYGENASE 1 AND NUCLEAR FACTOR (ERYTHROID-DERIVED 2)-LIKE 2 AND PROTECTS INTESTINAL EPITHELIAL CELLS FROM HEAT AND OXIDANT STRESS.” In Critical Care Medicine, 38:U19–U19. LIPPINCOTT WILLIAMS & WILKINS, 2010.Link to Item
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Higgins, David, Kelly Queensland, Alexandra Sufit, Daren Heyland, and Paul Wischmeyer. “IMPACT OF VITAMIN D DEFICIENCY ON OUTCOME IN CRITICALLY ILL PATIENTS.” In Critical Care Medicine, 38:U11–U11. LIPPINCOTT WILLIAMS & WILKINS, 2010.Link to Item
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Kallweit, Alyssa, Christine Hamiel Baird, Stefanie Niederlechner, Lauren Zager, Alexandra Sufit, and Paul Wischmeyer. “GLUTANHISIE'S MECHANISM OF CELLULAR PROTECTION AND HEAT SHOCK PROTEIN 25, 32 AND 70 ENHANCEMENT IS DEPENDENT ON THE HEXOSAMINE BIOSYNTHETIC PATHWAY IN HEAT STRESSED INTESTINAL EPITHELIAL CELLS.” In Critical Care Medicine, 38:U4–U4. LIPPINCOTT WILLIAMS & WILKINS, 2010.Link to Item
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Niederlechner, Stefanie, Jonathan Levi, Christine Hamiel Baird, Alyssa Kallweit, and Paul Wischmeyer. “L-GLUTAMINE'S PROTECTIVE MECHANISM VIA THE INTEGRIN/SRC PATHWAY IS DEPENDENT ON CELL SWELLING, O-GLYCOSYLATION, HSF-1, AND HSP EXPRESSION.” In Critical Care Medicine, 38:U4–U4. LIPPINCOTT WILLIAMS & WILKINS, 2010.Link to Item
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Baer, A., C. Hamiel, S. Cheng, E. Luzier, N. Pearlman, and P. E. Wischmeyer. “GOAL-DIRECTED INTRAVENOUS HEPARIN, BUT NOT SUBCUTANEOUS HEPARIN, NORMALIZES COAGULATION STATUS IN SICU PATIENTS.” In Shock, 33:29–30. LIPPINCOTT WILLIAMS & WILKINS, 2010.Link to Item
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Hamiel, C., and P. E. Wischmeyer. “GLUTAMINE TREATMENT INCREASES HSP32 BUT NOT HSP25 IN OXIDANT INJURED INTESTINAL EPITHELIAL CELLS.” In Shock, 33:35–35. LIPPINCOTT WILLIAMS & WILKINS, 2010.Link to Item
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Niederlechner, S., C. Hamiel, and P. E. Wischmeyer. “L-GLUTAMINE-MEDIATED CELLULAR PROTECTION, HSP70 EXPRESSION, AND O-GLYCOSYLATION IS DEPENDENT ON THE INTEGRIN OSMOSENSING PATHWAY.” In Shock, 33:23–23. LIPPINCOTT WILLIAMS & WILKINS, 2010.Link to Item
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Queensland, K., A. Edwards, L. B. Weitzel, D. Heyland, and P. E. Wischmeyer. “HEAT SHOCK PROTEIN 70 PREDICTS MORTALITY, INFECTION, AND HOSPITAL LENGTH OF STAY IN ADULT INTENSIVE CARE PATIENTS.” In Shock, 33:72–72. LIPPINCOTT WILLIAMS & WILKINS, 2010.Link to Item
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Sufit, A., C. Hamiel, A. Baer, K. Queensland, and P. E. Wischmeyer. “ORAL GLUTAMINE REDUCES MYOCARDIAL INJURY IN PATIENTS UNDERGOING CARDIAC SURGERY.” In Shock, 33:11–12. LIPPINCOTT WILLIAMS & WILKINS, 2010.Link to Item
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Weitzel, L., K. Queensland, P. Wischmeyer, and D. Heyland. “OPTIMIZING ENROLLMENT IN CLINICAL TRIALS OF ANTI-INFLAMMATORY THERAPY THROUGH IDENTIFICATION OF BIOMARKERS PRESENT AT ICU ADMISSION.” In Shock, 33:32–32. LIPPINCOTT WILLIAMS & WILKINS, 2010.Link to Item
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Xue, H., A. Sufit, and P. Wischmeyer. “GLUTAMINE UPREGULATES BOTH EXPRESSION AND TRANSACTIVATION ACTIVITY OF HSF-1 IN EXPERIMENTAL COLITIS.” In Shock, 33:11–11. LIPPINCOTT WILLIAMS & WILKINS, 2010.Link to Item
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Edwards, A. G., and P. E. Wischmeyer. “HSP-70 LEVELS DECLINE IN DECEASED CRITICALLY ILL PATIENTS, RISE IN ALIVE CRITICALLY ILL PATIENTS FOLLOWING ADMISSION TO THE ICU.” In Journal of Investigative Medicine, 58:146–47. BMJ PUBLISHING GROUP, 2010.Link to Item
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Edwards, A. G., and P. E. Wischmeyer. “HSP-70 LEVELS DECLINE IN DECEASED CRITICALLY ILL PATIENTS, RISE IN ALIVE CRITICALLY ILL PATIENTS FOLLOWING ADMISSION TO THE ICU.” In Journal of Investigative Medicine, 58:109–109. BMJ PUBLISHING GROUP, 2010.Link to Item
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Repine, J. J., A. C. Tan, C. J. Beehler, K. Crader, N. D. Elkins, J. Vina, P. Wilson, et al. “UNIQUE RAT STRAIN SURVIVES BREATHING PURE OXYGEN, EXERCISES AND LIVES LONGER: POSSIBLE ROLE FOR HEAT-SHOCK PROTEINS AND REDUCED INFLAMMATION.” In Journal of Investigative Medicine, 58:233–233. BMJ PUBLISHING GROUP, 2010.Link to Item
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Edwards, Anthony, Kelly Queensland, Christine Hamiel, Lindsay Weitzel, Daren Heyland, and Paul Wischmeyer. “COMPARED TO ICU PATIENTS ALIVE AT DAY 28, DECEASED ICU PATIENTS SHOW DECREASING LEVELS OF HSP70 AT DAY 7 OF HOSPITAL STAY.” In Critical Care Medicine, 37:A321–A321. LIPPINCOTT WILLIAMS & WILKINS, 2009.Link to Item
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Hamiel, Christine, Adam Cross, Alyssa Kallweit, Stefanie Niederlechner, and Paul Wischmeyer. “PHOSPHOINOSITIDE 3-KINASE PATHWAY INHIBITION ATTENUATES THREONINE-MEDIATED CELLULAR PROTECTION IN INTESTINAL EPITHELIAL CELLS.” In Critical Care Medicine, 37:A121–A121. LIPPINCOTT WILLIAMS & WILKINS, 2009.Link to Item
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Hamiel, Christine, Angie Baer, Elizabeth Luzier, Sara Cheng, Nathan Pearlman, and Paul Wischmeyer. “GOAL-DIRECTED INTRAVENOUS HEPARIN, BUT NOT SUBCUTANEOUS HEPARIN, NORMALIZES COAGULATION STATUS IN SICU PATIENTS.” In Critical Care Medicine, 37:A425–A425. LIPPINCOTT WILLIAMS & WILKINS, 2009.Link to Item
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Turpin, Robin, Paul Wischmeyer, Alessandro Pontes-Arruda, and Katie Williams. “BLOODSTREAM INFECTIONS AND ATTRIBUTABLE LENGTH OF STAY: DOES DELIVERY OF PARENTERAL NUTRITION VIA MULTI-CHAMBER BAG HAVE ANY IMPACT IN THE ICU?” In Critical Care Medicine, 37:A349–A349. LIPPINCOTT WILLIAMS & WILKINS, 2009.Link to Item
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Wischmeyer, Paul, Kelly Queensland, Connie Beehler, Nancy Elkins, Jonathan Repine, and John Repine. “HYPEROXIA TOLERANT RATS OVEREXPRESS LUNG HEME-OXYGENASE-1.” In Critical Care Medicine, 37:A169–A169. LIPPINCOTT WILLIAMS & WILKINS, 2009.Link to Item
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Wischmeyer, Paul, Lindsay Weitzel, Kelly Queensland, and Daren Heyland. “ELEVATED ADMISSION IL-8 LEVEL IS ASSOCIATED WITH MORTALITY IN CRITICALLY ILL ADULTS.” In Critical Care Medicine, 37:A229–A229. LIPPINCOTT WILLIAMS & WILKINS, 2009.Link to Item
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Hamiel, Christine R., Alyssa Kallweit, Paul E. Wischmeyer, and Ryan Beck. “L-THREONINE INDUCES CYTOPLASMIC HEAT SHOCK PROTEIN 25 AND INCREASES INTESTINAL CELL SURVIVAL FOLLOWING INJURY.” In Critical Care Medicine, 36:A28–A28. LIPPINCOTT WILLIAMS & WILKINS, 2008.Link to Item
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Hamiel, Christine R., and Paul E. Wischmeyer. “HEAT SHOCK FACTOR-1 IS MODIFIED BY GLUTAMINE MEDIATED O-LINKED-GLYCOSYLATION.” In Critical Care Medicine, 36:A3–A3. LIPPINCOTT WILLIAMS & WILKINS, 2008.Link to Item
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Wilson, J. E., N. Kiselanova, Q. Stevens, R. Lutz, T. Mandler, Z. V. Tran, and P. E. Wischmeyer. “A survey of inhalational anaesthetic abuse in anaesthesia training programmes.” In Anaesthesia, 63:616–20, 2008. https://doi.org/10.1111/j.1365-2044.2008.05444.x.Full Text Link to Item
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Hamiel, C. R., J. Henderson, A. Kallweit, D. Richter, and P. E. Wischmeyer. “P38 MAP kinase inhibition decreases glutamine meidated HSP70 expression and cellular protection.” In Shock, 29:57–58. LIPPINCOTT WILLIAMS & WILKINS, 2008.Link to Item
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Singleton, Kristen D., and Paul E. Wischmeyer. “Glutamine induces heat shock protein expression via O-glycosylation and phosphorylation of HSF-1 and SPI.” In Shock, 29:91–91. LIPPINCOTT WILLIAMS & WILKINS, 2008.Link to Item
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Hamiel, Christine R., Jane Henderson, Alyssa Kallweit, Don Richter, and Paul Wischmeyer. “P38 map kinase inhibition decreases glutamine mediated hsp70 expression.” In Critical Care Medicine, 35:A32–A32. LIPPINCOTT WILLIAMS & WILKINS, 2007.Link to Item
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Landzinski, James, Tyree Kiser, Douglas Fish, Robert MacLaren, and Paul Wischmeyer. “Gastric motility function in critically-ill patients tolerant versus intolerant to gastric nutrition.” In Critical Care Medicine, 35:A193–A193. LIPPINCOTT WILLIAMS & WILKINS, 2007.Link to Item
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MacLaren, Robert, Tyree Kiser, Douglas Fish, and Paul Wischmeyer. “Erythromycin versus metoclopramide for facilitating gastric emptying and tolerance to intra-gastric nutrition.” In Critical Care Medicine, 35:A192–A192. LIPPINCOTT WILLIAMS & WILKINS, 2007.Link to Item
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Singleton, Kristen, and Paul Wischmeyer. “Tissue specific sirna knock down of O-GlcNAc transferase (OGT) in the gut impairs heat shock protein expression.” In Critical Care Medicine, 35:A34–A34. LIPPINCOTT WILLIAMS & WILKINS, 2007.Link to Item
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Wilson, Joel E., Haley C. Gallup, Kristen D. Singleton, and Paul E. Wischmeyer. “Propranolol improves survival following experimental sepsis in rodents.” In Critical Care Medicine, 35:A110–A110. LIPPINCOTT WILLIAMS & WILKINS, 2007.Link to Item
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Hamiel, C., S. Pinto, K. Singleton, and P. E. Wischmeyer. “Glutamine treatment increases cell viabilily in heat stressed murine embryonic fibroblast cells via activation of the O-linked-N-acetyglucosamine pathway.” In Shock, 27:36–37. LIPPINCOTT WILLIAMS & WILKINS, 2007.Link to Item
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Singleton, K., and P. Wischmeyer. “Gln attenuates inflammation following sepsis through loss of Cul-1 neddylation and thereby inhibits NF-kappa B activation and IKB-alpha degredation.” In Shock, 27:41–41. LIPPINCOTT WILLIAMS & WILKINS, 2007.Link to Item
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Hamiel, Christine, Shanti Pinto, and Paul E. Wischmeyer. “MOLECULAR MECHANISM OF GLN INDUCTION OF HSP70 INVOLVES ACTIVATION OF THE O-LINKED-N-ACETYLGLUCOSAMINE PATHWAY.” In Critical Care Medicine, 34:A27–A27. Ovid Technologies (Wolters Kluwer Health), 2006. https://doi.org/10.1097/00003246-200612002-00101.Full Text
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Singleton, Kristen, Christine Hamiel, Shanti Pinto, and Paul E. Wischmeyer. “GLUCOSAMINE INCREASES HSP70 EXPRESSION IN VITRO AND IN VIVO FOLLOWING INJURY.” In Critical Care Medicine, 34:A27–A27. Ovid Technologies (Wolters Kluwer Health), 2006. https://doi.org/10.1097/00003246-200612002-00102.Full Text
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Peng, Z. Y., C. Hamiel, and P. E. Wischmeyer. “GLUTAMINE ATTENUATES INFLAMMATIONINDUCED MEDIATORS OF PRO-INFLAMMATORY RESPONSE AND ENHANCES HSP-70 IN TYPE II LUNG EPITHELIAL CELLS.” In Shock, 25:23–23. Ovid Technologies (Wolters Kluwer Health), 2006. https://doi.org/10.1097/00024382-200606001-00070.Full Text
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Singleton, K., Z. V. Tran, and P. E. Wischmeyer. “GLUTAMINE'S ATTENUATION OF NF-kB AND MORTALITY FOLLOWING SEPSIS ARE DEPENDENT ON HSP-70 EXPRESSION.” In Shock, 25:8–8. Ovid Technologies (Wolters Kluwer Health), 2006. https://doi.org/10.1097/00024382-200606001-00023.Full Text
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Wischmeyer, P. E., A. Morrison, K. Singleton, K. Odoms, and H. R. Wong. “GLUTAMINE ENHANCES HEAT SHOCK FACTOR-1 NUCLEAR TRANSLOCATION, PHOSHORYLATION AND PROMOTER BINDING FOLLOWING HEAT STRESS INJURY.” In Shock, 25:63–63. Ovid Technologies (Wolters Kluwer Health), 2006. https://doi.org/10.1097/00024382-200606001-00191.Full Text
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MacLaren, R., D. Fish, T. Kiser, E. Abraham, and P. Wischmeyer. “Erythromycin vs. metoclopramide for facilitating gastric emptying and tolerance to intragastric nutrition.” In Critical Care Medicine, 33:A97–A97. LIPPINCOTT WILLIAMS & WILKINS, 2005.Link to Item
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Roller, Evan, and Paul E. Wischmeyer. “HEAT SHOCK PROTEIN-70 IS A KEY MEDIATOR OF GLUTAMINEʼs PROTECTION AGAINST INJURY.” In Critical Care Medicine, 33:A31–A31. Ovid Technologies (Wolters Kluwer Health), 2005. https://doi.org/10.1097/00003246-200512002-00119.Full Text
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Singleton, Kristen D., and Paul E. Wischmeyer. “HSP-70 KNOCK-OUT MICE DEMONSTRATE ENHANCED NF-KB ACTIVATION AND MORTALITY FOLLOWING SEPSIS.” In Critical Care Medicine, 33:A135–A135. Ovid Technologies (Wolters Kluwer Health), 2005. https://doi.org/10.1097/00003246-200512002-00478.Full Text
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Singleton, Kristen D., and Paul E. Wischmeyer. “ORAL GLUTAMINE DECREASES GUT PERMEABILITY AND IMPROVES SURVIVAL FOLLOWING HEAT STROKE: ROLE OF HEAT SHOCK PROTEIN EXPRESSION.” In Critical Care Medicine, 33:A34–A34. Ovid Technologies (Wolters Kluwer Health), 2005. https://doi.org/10.1097/00003246-200512002-00126.Full Text
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Morrison, A., and P. Wischmeyer. “Inhibition of protein kinase C activity prevents glutamine mediated HSP-70 induction and cellular protection.” In Shock, 23:73–73. LIPPINCOTT WILLIAMS & WILKINS, 2005.Link to Item
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Singleton, K., V. Beckey, and P. Wischmeyer. “Glutamine attenuates pulmonary NF-kappa B activation, inflammatory cytokine release, and prevents the acute respiratory distress syndrome (ARDS) following sepsis.” In Shock, 23:5–5. LIPPINCOTT WILLIAMS & WILKINS, 2005.Link to Item
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Singleton, K. D., T. R. Ziegler, M. Luo, C. Fernandez-Estivariz, and P. E. Wischmeyer. “INTRAVENOUS GLUTAMINE INCREASES SERUM HSP 72 LEVELS IN BOTH HUMANS AND RODENTS FOLLOWING SYSTEMIC INFLAMMATION.” In Shock, 21:84–84. Ovid Technologies (Wolters Kluwer Health), 2004. https://doi.org/10.1097/00024382-200406002-00250.Full Text
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Wischmeyer, P. E., K. Singleton, and N. Serkova. “Glutamine attenuates multiple pathways of sepsis-induced injury and improves survival following peritonitis: Role of heat stress protein pathway manipulation.” In Critical Care Medicine, 31:A47–A47. LIPPINCOTT WILLIAMS & WILKINS, 2003.Link to Item
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Singleton, Kristen D., and Paul E. Wischmeyer. “MORTALITY FOLLOWING CECAL LIGATION AND DOUBLE PUNCTURE ARE DEPENDENT ON LENGTH OF CECUM LIGATED.” In Critical Care Medicine, 30:A50–A50. Ovid Technologies (Wolters Kluwer Health), 2002. https://doi.org/10.1097/00003246-200212001-00175.Full Text
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Wischmeyer, Paul E., and Kristen D. Singleton. “POST-TREATMENT WITH SINGLE DOSE OF GLUTAMINE ATTENUATES IL-18 EXPRESSION AND REDUCES POLYMICROBIAL SEPSIS-INDUCED MORTALITY.” In Critical Care Medicine, 30:A11–A11. Ovid Technologies (Wolters Kluwer Health), 2002. https://doi.org/10.1097/00003246-200212001-00039.Full Text
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- Teaching & Mentoring
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Advising & Mentoring
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Dr. Wischmeyer is passionate about the mentorship and development of trainees at all levels interested in careers in as physician-scientists and academic medicine. Mentoring junior faculty, trainees and colleagues has been and will continue to be a top priority of my career. It my hope to be able to assist trainees in a range of specialties including anesthesiology, critical care, surgery, and nutrition to help create the future academic leaders in these specialties.
Overall, I am an advocate for mentorship with the goal of allowing mentees to move towards a research topic they are passionate about (as opposed to only their mentors research alone ). This is so their research becomes a life-long career passion , regardless of the challenges an academic career may present. This is accompanied by a hands-on and pro-active mentorship style to allow mentee’s to make well-informed decisions after exposure to appropriate expertise and acquisition of required skills to move towards becoming independent investigators in clinical, basic, and translational science research.
My mentoring track record includes successfully mentorship of many (> 20) highly motivated investigators at the level of fellow or junior faculty. All these investigators published original manuscripts (83% of which he serves as a co- or senior author) and have been invited to present their research at major national or international meetings. Many have won awards for their research during the period he mentored them with 94% remaining in academic medicine and 88% receiving independent funding. This is an exceptionally high percentage of mentees remaining in academic medicine. In addition he has worked with > 40 high school, undergraduate, medical students, dieticians, PhD students, and resident trainees. Many have had success publishing and presenting their research at national/international meetings. In total, my trainees have produced >70 manuscripts (>50 as first author) in which he serves as co-author and > 100 abstracts while under his mentorship. Overall, I have had mentee’s at all levels go on to receive peer reviewed funding (15 total individuals). I have served as a mentor on many of these trainee’s grants (9) and as an mentor on 2 NIH K23 funded grants and co-mentor on 1 funded K23 grant.
Available to mentor:
- Faculty
- Fellow
- Other
- PhD
- Post-Doc
- Resident
- Undergraduate
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Dr. Wischmeyer is passionate about the mentorship and development of trainees at all levels interested in careers in as physician-scientists and academic medicine. Mentoring junior faculty, trainees and colleagues has been and will continue to be a top priority of my career. It my hope to be able to assist trainees in a range of specialties including anesthesiology, critical care, surgery, and nutrition to help create the future academic leaders in these specialties.
- Scholarly, Clinical, & Service Activities
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Presentations & Appearances
- Nutrition Care in the Obese ICU and COVID-19 Patient. International Society of Intensive Care and Emergency Medicine. July 2021 2021
- Nutrition and Metabolic Care in COVID-19 with Dr Paul Wischmeyer. Society of Critical Care Medicine SE Chapter. July 2021 2021
- We Must Improve Post-ICU Rehabilitation! Strategies for Rehabilitation from Critical Care. International Society of Intensive Care and Emergency Medicine. July 2021 2021
- One Easy Step To Protect Against COVID-19: Probiotic Protection Against COVID-19-PROTECT-EHC Trial. Society of Critical Care Medicine. 2021 2021
- Surgical and Perioperative Nutrition Care and Optimization: We Must Do Better!. Evidence Based Perioperative Medicine (EBPOM) Congress. December 2020 2020
- What Patients Need Doctors to Know” -Keeping the CARE in “HealthCARE. Samuel Thompson Rowling Lecture. Royal College of Anesthesia. May 2019 2019
- Early Mobility in the ICU- A Multidisciplinary Journey. 2019 2019
- Are You Ready for Surgery?: The Three Key Surgical Malnutrition Questions You Must Ask. Abbott Nutrition Health Institute (ANHI). July 2018 2018
- What Nutrition Means to Me: Dr Paul Wischmeyer. Hospital Malnutrition and Nutriiton Delivery . ANHI . March 11, 2018 2018
- Interview on my Experience as ICU Patient and Physician and Essential Role of Early Mobility In ICU- Motion Means Life! . March 2018 2018
- Power of Protein in Recovery from ICU and Illness: Paul Wischmeyer M.D.. 2018 2018
- Surviving the ICU-The Patient Experience: What Patients Need Their Doctors to Know. 2016 2016
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Service to the Profession
Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.