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Artificial womb technology - A more physiologic solution to treating extreme prematurity.

Publication ,  Journal Article
De Bie, FR; Binion, CC; Antiel, RM
Published in: Eur J Obstet Gynecol Reprod Biol X
March 2025

Treatment of extreme premature infants (EPI) is limited by developmental immaturity primarily of the lung. A paradigm shift towards a more physiologic treatment of EPI as fetal neonates or fetonates, by keeping them in a womb-like environment to allow continued organ maturation, is the rationale for artificial womb technology. In this review, we discuss the artificial placenta and womb technology, it's rationale, the history of its development, the most recent preclinical models described in the literature and finally pertinent ethical considerations.

Duke Scholars

Published In

Eur J Obstet Gynecol Reprod Biol X

DOI

EISSN

2590-1613

Publication Date

March 2025

Volume

25

Start / End Page

100359

Location

Netherlands

Related Subject Headings

  • 3215 Reproductive medicine
 

Citation

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MLA
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De Bie, F. R., Binion, C. C., & Antiel, R. M. (2025). Artificial womb technology - A more physiologic solution to treating extreme prematurity. Eur J Obstet Gynecol Reprod Biol X, 25, 100359. https://doi.org/10.1016/j.eurox.2024.100359
De Bie, Felix R., Chase C. Binion, and Ryan M. Antiel. “Artificial womb technology - A more physiologic solution to treating extreme prematurity.Eur J Obstet Gynecol Reprod Biol X 25 (March 2025): 100359. https://doi.org/10.1016/j.eurox.2024.100359.
De Bie FR, Binion CC, Antiel RM. Artificial womb technology - A more physiologic solution to treating extreme prematurity. Eur J Obstet Gynecol Reprod Biol X. 2025 Mar;25:100359.
De Bie, Felix R., et al. “Artificial womb technology - A more physiologic solution to treating extreme prematurity.Eur J Obstet Gynecol Reprod Biol X, vol. 25, Mar. 2025, p. 100359. Pubmed, doi:10.1016/j.eurox.2024.100359.
De Bie FR, Binion CC, Antiel RM. Artificial womb technology - A more physiologic solution to treating extreme prematurity. Eur J Obstet Gynecol Reprod Biol X. 2025 Mar;25:100359.
Journal cover image

Published In

Eur J Obstet Gynecol Reprod Biol X

DOI

EISSN

2590-1613

Publication Date

March 2025

Volume

25

Start / End Page

100359

Location

Netherlands

Related Subject Headings

  • 3215 Reproductive medicine