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Chromatin Immunoprecipitation (ChIP) Using Drosophila Antennal and Brain Samples.

Publication ,  Journal Article
Du, C; Volkan, P
Published in: Cold Spring Harbor protocols
January 2025

Chromatin immunoprecipitation (ChIP) is a common approach for studying the binding pattern of proteins on DNA sequences or the landscape of histones with different marks throughout the genome. ChIP is used on various organisms, including Drosophila This protocol provides a detailed overview of the immunoprecipitation portion of a ChIP procedure from samples of Drosophila nervous systems, specifically antennae and brains, that have already been fixed and sheared. These methods can be applied to other tissues of interest after optimizing for sample size and other relevant parameters.

Duke Scholars

Published In

Cold Spring Harbor protocols

DOI

EISSN

1559-6095

ISSN

1940-3402

Publication Date

January 2025

Volume

2025

Issue

1

Start / End Page

pdb.prot108142

Related Subject Headings

  • Drosophila
  • DNA
  • Chromatin Immunoprecipitation
  • Brain
  • Arthropod Antennae
  • Animals
  • 3101 Biochemistry and cell biology
  • 1103 Clinical Sciences
  • 0601 Biochemistry and Cell Biology
  • 0306 Physical Chemistry (incl. Structural)
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Du, C., & Volkan, P. (2025). Chromatin Immunoprecipitation (ChIP) Using Drosophila Antennal and Brain Samples. Cold Spring Harbor Protocols, 2025(1), pdb.prot108142. https://doi.org/10.1101/pdb.prot108142
Du, Chengcheng, and Pelin Volkan. “Chromatin Immunoprecipitation (ChIP) Using Drosophila Antennal and Brain Samples.Cold Spring Harbor Protocols 2025, no. 1 (January 2025): pdb.prot108142. https://doi.org/10.1101/pdb.prot108142.
Du C, Volkan P. Chromatin Immunoprecipitation (ChIP) Using Drosophila Antennal and Brain Samples. Cold Spring Harbor protocols. 2025 Jan;2025(1):pdb.prot108142.
Du, Chengcheng, and Pelin Volkan. “Chromatin Immunoprecipitation (ChIP) Using Drosophila Antennal and Brain Samples.Cold Spring Harbor Protocols, vol. 2025, no. 1, Jan. 2025, p. pdb.prot108142. Epmc, doi:10.1101/pdb.prot108142.
Du C, Volkan P. Chromatin Immunoprecipitation (ChIP) Using Drosophila Antennal and Brain Samples. Cold Spring Harbor protocols. 2025 Jan;2025(1):pdb.prot108142.

Published In

Cold Spring Harbor protocols

DOI

EISSN

1559-6095

ISSN

1940-3402

Publication Date

January 2025

Volume

2025

Issue

1

Start / End Page

pdb.prot108142

Related Subject Headings

  • Drosophila
  • DNA
  • Chromatin Immunoprecipitation
  • Brain
  • Arthropod Antennae
  • Animals
  • 3101 Biochemistry and cell biology
  • 1103 Clinical Sciences
  • 0601 Biochemistry and Cell Biology
  • 0306 Physical Chemistry (incl. Structural)