Genetic and biomarker disclosure process in a memory and aging study.
Publication
, Journal Article
Mayan, I; Roth, H; Ghosh, D; Whitson, HE; Johnson, KG
Published in: J Alzheimers Dis
March 2025
Despite growing awareness that disclosing biomarker results to research participants is aligned with ethical principles of researcher-participant partnership, there are currently no widely adopted guidelines for this disclosure in Alzheimer's disease research. We developed a process and tools to deliver biomarker and genetic results to 65 participants of The Memory and Aging Study of the Duke-UNC Alzheimer's Disease Research Center (ADRC). Survey responses of 46 participants were analyzed. We show high participant satisfaction and lower anxiety levels after receiving the results. The developed process and materials provide a template for standardized Alzheimer's disease biomarker result delivery in the research setting.
Duke Scholars
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Published In
J Alzheimers Dis
DOI
EISSN
1875-8908
Publication Date
March 2025
Volume
104
Issue
2
Start / End Page
312 / 318
Location
United States
Related Subject Headings
- Neurology & Neurosurgery
- Middle Aged
- Memory
- Male
- Humans
- Female
- Disclosure
- Biomarkers
- Alzheimer Disease
- Aging
Citation
APA
Chicago
ICMJE
MLA
NLM
Mayan, I., Roth, H., Ghosh, D., Whitson, H. E., & Johnson, K. G. (2025). Genetic and biomarker disclosure process in a memory and aging study. J Alzheimers Dis, 104(2), 312–318. https://doi.org/10.1177/13872877251315957
Mayan, Inbal, Heidi Roth, Dhrubajyoti Ghosh, Heather E. Whitson, and Kim G. Johnson. “Genetic and biomarker disclosure process in a memory and aging study.” J Alzheimers Dis 104, no. 2 (March 2025): 312–18. https://doi.org/10.1177/13872877251315957.
Mayan I, Roth H, Ghosh D, Whitson HE, Johnson KG. Genetic and biomarker disclosure process in a memory and aging study. J Alzheimers Dis. 2025 Mar;104(2):312–8.
Mayan, Inbal, et al. “Genetic and biomarker disclosure process in a memory and aging study.” J Alzheimers Dis, vol. 104, no. 2, Mar. 2025, pp. 312–18. Pubmed, doi:10.1177/13872877251315957.
Mayan I, Roth H, Ghosh D, Whitson HE, Johnson KG. Genetic and biomarker disclosure process in a memory and aging study. J Alzheimers Dis. 2025 Mar;104(2):312–318.
Published In
J Alzheimers Dis
DOI
EISSN
1875-8908
Publication Date
March 2025
Volume
104
Issue
2
Start / End Page
312 / 318
Location
United States
Related Subject Headings
- Neurology & Neurosurgery
- Middle Aged
- Memory
- Male
- Humans
- Female
- Disclosure
- Biomarkers
- Alzheimer Disease
- Aging