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Assessment of age-related variation in cervical neuroforaminal dimensions.

Publication ,  Journal Article
Nguyen, K; Brandt, Z; Shin, D; Kubba, R; Vyhmeister, E; Razzouk, J; Shaffrey, C; Cheng, W; Danisa, O
Published in: J Clin Neurosci
April 2025

Radiographic parameters for diagnosing cervical neuroforaminal stenosis (CNFS) are not well described. To develop definitive criteria for diagnosis of CNFS, a standardized baseline of average neuroforaminal dimensions must first be established. Thus, the aim of this study was to: (1) use computed tomography (CT) of patients without neck pain or spinal pathology to establish mean cervical neuroforaminal dimensions (CNFD) across multiple age groups and (2) assess differences in CNFD by age. Cervical CT scans of 1,457 asymptomatic patients were reviewed to measure CNFD, defined as follows: axial width, craniocaudal height, and area. Patients were divided into four groups based on age: 18-35, 36-50, 51-64, and 65 + years. Statistical analyses were used to assess differences in CNFD according to age group.Mean overall CNFD for the 18-35 year-old cohort were 6.43 mm for width, 9.28 mm for height, and 58.85 mm2 for area. For the 36-50 year-old cohort, dimensions were 5.89 mm for width, 8.63 mm for height, and 52.78 mm2 for area. For the 51-64 year-old cohort, dimensions were 5.29 mm for width, 8.52 mm for height, and 48.93 mm2 for area. Finally, the 65 + year-old cohort had dimensions of 5.09 mm for width, 8.16 mm for height, and 45.91 mm2 for area. Significant differences in CNFD were observed between age groups, with dimensions decreasing in size from the younger to older age groups. In the studied population, CNFD decreased progressively with age. The results of our study may have utility in the diagnosis of CNFS.

Duke Scholars

Published In

J Clin Neurosci

DOI

EISSN

1532-2653

Publication Date

April 2025

Volume

134

Start / End Page

111095

Location

Scotland

Related Subject Headings

  • Young Adult
  • Tomography, X-Ray Computed
  • Spinal Stenosis
  • Retrospective Studies
  • Neurology & Neurosurgery
  • Middle Aged
  • Male
  • Humans
  • Female
  • Cervical Vertebrae
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Nguyen, K., Brandt, Z., Shin, D., Kubba, R., Vyhmeister, E., Razzouk, J., … Danisa, O. (2025). Assessment of age-related variation in cervical neuroforaminal dimensions. J Clin Neurosci, 134, 111095. https://doi.org/10.1016/j.jocn.2025.111095
Nguyen, Kai, Zachary Brandt, David Shin, Rohan Kubba, Ethan Vyhmeister, Jacob Razzouk, Christopher Shaffrey, Wayne Cheng, and Olumide Danisa. “Assessment of age-related variation in cervical neuroforaminal dimensions.J Clin Neurosci 134 (April 2025): 111095. https://doi.org/10.1016/j.jocn.2025.111095.
Nguyen K, Brandt Z, Shin D, Kubba R, Vyhmeister E, Razzouk J, et al. Assessment of age-related variation in cervical neuroforaminal dimensions. J Clin Neurosci. 2025 Apr;134:111095.
Nguyen, Kai, et al. “Assessment of age-related variation in cervical neuroforaminal dimensions.J Clin Neurosci, vol. 134, Apr. 2025, p. 111095. Pubmed, doi:10.1016/j.jocn.2025.111095.
Nguyen K, Brandt Z, Shin D, Kubba R, Vyhmeister E, Razzouk J, Shaffrey C, Cheng W, Danisa O. Assessment of age-related variation in cervical neuroforaminal dimensions. J Clin Neurosci. 2025 Apr;134:111095.
Journal cover image

Published In

J Clin Neurosci

DOI

EISSN

1532-2653

Publication Date

April 2025

Volume

134

Start / End Page

111095

Location

Scotland

Related Subject Headings

  • Young Adult
  • Tomography, X-Ray Computed
  • Spinal Stenosis
  • Retrospective Studies
  • Neurology & Neurosurgery
  • Middle Aged
  • Male
  • Humans
  • Female
  • Cervical Vertebrae