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Identifying consensus and areas for future research in chondrosarcoma : a report from the Birmingham Orthopaedic Oncology Meeting.

Publication ,  Journal Article
Jeys, LM; Morris, GV; Kurisunkal, VJ; Botello, E; Boyle, RA; Ebeid, W; Houdek, MT; Puri, A; Ruggieri, P; Brennan, B; Laitinen, MK; Abood, AA ...
Published in: Bone Joint J
February 1, 2025

AIMS: The Birmingham Orthopaedic Oncology Meeting (BOOM), held in January 2024, convened 309 delegates from 53 countries to discuss and refine 21 consensus statements on the optimal management of chondrosarcoma. METHODS: With representation from Europe (43%; n = 133), North America (17%; n = 53), South America (16%; n = 49), Asia (13%; n = 40), Australasia (5%; n = 16), the Middle East (4%; n = 12), and Africa (2%; n = 6), the combined experience of treating bone sarcomas among attendees totalled approximately 30,000 cases annually, equivalent to 66 years of experience in the UK alone. The meeting's process began with the formation of a local organizing committee, regional leads, and a scientific committee comprising representatives from 150 specialist units across 47 countries. Supported by major orthopaedic oncology organizations, the meeting used a modified Delphi process to develop consensus statements through online questionnaires, thematic groupings, narrative reviews, and anonymous pre-meeting polling. RESULTS: Strong (> 80%) consensus was achieved on 19 out of 21 statements, reflecting agreement among delegates. Key areas of consensus included the role of radiology in diagnosis and surveillance, the management of locally recurrent disease, and the treatment of dedifferentiated chondrosarcoma. Notably, there was agreement that routine chemotherapy has no role in chondrosarcoma treatment, and radiological surveillance is safe for intraosseous chondrosarcomas. Despite the overall consensus, areas of controversy remain, particularly regarding the treatment of atypical cartilage tumours and surgical margins. These unresolved issues underscore the need for further research and collaboration within the orthopaedic oncology community. CONCLUSION: BOOM represents the largest global consensus meeting in orthopaedic oncology, providing valuable guidance for clinicians managing chondrosarcoma worldwide. The consensus statements offer a reference for clinical practice, highlight key research priorities, and aim to improve patient outcomes on a global scale.

Duke Scholars

Published In

Bone Joint J

DOI

EISSN

2049-4408

Publication Date

February 1, 2025

Volume

107-B

Issue

2

Start / End Page

246 / 252

Location

England

Related Subject Headings

  • Orthopedics
  • Humans
  • Delphi Technique
  • Consensus
  • Chondrosarcoma
  • Bone Neoplasms
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Jeys, L. M., Morris, G. V., Kurisunkal, V. J., Botello, E., Boyle, R. A., Ebeid, W., … Campanacci, D. A. (2025). Identifying consensus and areas for future research in chondrosarcoma : a report from the Birmingham Orthopaedic Oncology Meeting. Bone Joint J, 107-B(2), 246–252. https://doi.org/10.1302/0301-620X.107B2.BJJ-2024-0643.R1
Jeys, Lee M., Guy V. Morris, Vineet J. Kurisunkal, Eduardo Botello, Richard A. Boyle, Walid Ebeid, Matthew T. Houdek, et al. “Identifying consensus and areas for future research in chondrosarcoma : a report from the Birmingham Orthopaedic Oncology Meeting.Bone Joint J 107-B, no. 2 (February 1, 2025): 246–52. https://doi.org/10.1302/0301-620X.107B2.BJJ-2024-0643.R1.
Jeys LM, Morris GV, Kurisunkal VJ, Botello E, Boyle RA, Ebeid W, et al. Identifying consensus and areas for future research in chondrosarcoma : a report from the Birmingham Orthopaedic Oncology Meeting. Bone Joint J. 2025 Feb 1;107-B(2):246–52.
Jeys, Lee M., et al. “Identifying consensus and areas for future research in chondrosarcoma : a report from the Birmingham Orthopaedic Oncology Meeting.Bone Joint J, vol. 107-B, no. 2, Feb. 2025, pp. 246–52. Pubmed, doi:10.1302/0301-620X.107B2.BJJ-2024-0643.R1.
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Published In

Bone Joint J

DOI

EISSN

2049-4408

Publication Date

February 1, 2025

Volume

107-B

Issue

2

Start / End Page

246 / 252

Location

England

Related Subject Headings

  • Orthopedics
  • Humans
  • Delphi Technique
  • Consensus
  • Chondrosarcoma
  • Bone Neoplasms