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What's old is new again: opioid and benzodiazepine actions on ventilation, a reminder of the importance of knowing one's drugs.

Publication ,  Journal Article
Meissner, K; Kharasch, ED
Published in: Br J Anaesth
April 2025

Co-administering opioids and benzodiazepines can have deleterious effects on ventilation. However, little is known about the underlying mechanisms leading to hypoventilation. A recent article in the British Journal of Anaesthesia is not just another reminder of the hazards of combining opioids with benzodiazepines or other sedatives, but also applies mechanistic understanding to guide informed practice and future pharmaceutical development.

Duke Scholars

Published In

Br J Anaesth

DOI

EISSN

1471-6771

Publication Date

April 2025

Volume

134

Issue

4

Start / End Page

903 / 905

Location

England

Related Subject Headings

  • Respiration
  • Hypoventilation
  • Hypnotics and Sedatives
  • Humans
  • Drug Interactions
  • Benzodiazepines
  • Anesthesiology
  • Analgesics, Opioid
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Meissner, K., & Kharasch, E. D. (2025). What's old is new again: opioid and benzodiazepine actions on ventilation, a reminder of the importance of knowing one's drugs. Br J Anaesth, 134(4), 903–905. https://doi.org/10.1016/j.bja.2025.01.014
Meissner, Konrad, and Evan D. Kharasch. “What's old is new again: opioid and benzodiazepine actions on ventilation, a reminder of the importance of knowing one's drugs.Br J Anaesth 134, no. 4 (April 2025): 903–5. https://doi.org/10.1016/j.bja.2025.01.014.
Meissner, Konrad, and Evan D. Kharasch. “What's old is new again: opioid and benzodiazepine actions on ventilation, a reminder of the importance of knowing one's drugs.Br J Anaesth, vol. 134, no. 4, Apr. 2025, pp. 903–05. Pubmed, doi:10.1016/j.bja.2025.01.014.
Journal cover image

Published In

Br J Anaesth

DOI

EISSN

1471-6771

Publication Date

April 2025

Volume

134

Issue

4

Start / End Page

903 / 905

Location

England

Related Subject Headings

  • Respiration
  • Hypoventilation
  • Hypnotics and Sedatives
  • Humans
  • Drug Interactions
  • Benzodiazepines
  • Anesthesiology
  • Analgesics, Opioid
  • 3202 Clinical sciences
  • 1103 Clinical Sciences