Wide Margins are Still Relevant: A Case of a Well-Circumscribed Borderline Phyllodes Tumor With a Satellite Nodule in a Re-excision Margin.
Publication
, Journal Article
Reason, EH; Sotolongo, G; Bentley, RC; Factor, RE; Jeck, WR; Rosenberger, LH
Published in: Cureus
March 2025
Phyllodes tumors (PTs) of the breast are rare fibroepithelial neoplasms with high rates of local recurrence (LR) for which surgical excision remains the mainstay of treatment. The recommended surgical margin width is debated and varies based on the histologic grade. We present a case of a middle-aged woman with a well-circumscribed borderline PT who underwent margin re-excision, with a distinct focus of the PT detected at a previously negative margin. Given the high rates of LR and potential for histologic upgrade at the time of recurrence, combined with the current limited understanding of peritumoral tissue and possible satellite foci, a wide negative margin remains the recommendation for borderline PTs.
Duke Scholars
Published In
Cureus
DOI
ISSN
2168-8184
Publication Date
March 2025
Volume
17
Issue
3
Start / End Page
e79890
Location
United States
Related Subject Headings
- 42 Health sciences
- 32 Biomedical and clinical sciences
- 11 Medical and Health Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Reason, E. H., Sotolongo, G., Bentley, R. C., Factor, R. E., Jeck, W. R., & Rosenberger, L. H. (2025). Wide Margins are Still Relevant: A Case of a Well-Circumscribed Borderline Phyllodes Tumor With a Satellite Nodule in a Re-excision Margin. Cureus, 17(3), e79890. https://doi.org/10.7759/cureus.79890
Reason, Ellery H., Gina Sotolongo, Rex C. Bentley, Rachel E. Factor, William R. Jeck, and Laura H. Rosenberger. “Wide Margins are Still Relevant: A Case of a Well-Circumscribed Borderline Phyllodes Tumor With a Satellite Nodule in a Re-excision Margin.” Cureus 17, no. 3 (March 2025): e79890. https://doi.org/10.7759/cureus.79890.
Reason EH, Sotolongo G, Bentley RC, Factor RE, Jeck WR, Rosenberger LH. Wide Margins are Still Relevant: A Case of a Well-Circumscribed Borderline Phyllodes Tumor With a Satellite Nodule in a Re-excision Margin. Cureus. 2025 Mar;17(3):e79890.
Reason, Ellery H., et al. “Wide Margins are Still Relevant: A Case of a Well-Circumscribed Borderline Phyllodes Tumor With a Satellite Nodule in a Re-excision Margin.” Cureus, vol. 17, no. 3, Mar. 2025, p. e79890. Pubmed, doi:10.7759/cureus.79890.
Reason EH, Sotolongo G, Bentley RC, Factor RE, Jeck WR, Rosenberger LH. Wide Margins are Still Relevant: A Case of a Well-Circumscribed Borderline Phyllodes Tumor With a Satellite Nodule in a Re-excision Margin. Cureus. 2025 Mar;17(3):e79890.
Published In
Cureus
DOI
ISSN
2168-8184
Publication Date
March 2025
Volume
17
Issue
3
Start / End Page
e79890
Location
United States
Related Subject Headings
- 42 Health sciences
- 32 Biomedical and clinical sciences
- 11 Medical and Health Sciences