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Encyclopedia of Cancer Third Edition Volumes 1 3

Helicobacter Pylori-Mediated Carcinogenesis

Publication ,  Chapter
Varga, MG; Epplein, M
January 1, 2018

Helicobacter pylori is the most successful bacterial pathogen worldwide, coevolving with humans for millennia and currently infecting over 50% of the global populous. It is a Gram-negative, spiral-shaped organism that can evade the immune response for the lifetime of its host. The identification of H. pylori as an etiological agent of gastric adenocarcinoma led to its classification as a class I carcinogen. Improved hygiene and targeted eradication with antibiotic therapy have been efficacious in reducing the incidence of gastric cancer, but the opportunity remains to further reduce the burden of H. pylori-associated disease through testing and treatment of high-risk populations.

Duke Scholars

DOI

Publication Date

January 1, 2018

Volume

2

Start / End Page

V2 / 197
 

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Varga, M. G., & Epplein, M. (2018). Helicobacter Pylori-Mediated Carcinogenesis. In Encyclopedia of Cancer Third Edition Volumes 1 3 (Vol. 2, pp. V2-197). https://doi.org/10.1016/B978-0-12-801238-3.65172-3
Varga, M. G., and M. Epplein. “Helicobacter Pylori-Mediated Carcinogenesis.” In Encyclopedia of Cancer Third Edition Volumes 1 3, 2:V2-197, 2018. https://doi.org/10.1016/B978-0-12-801238-3.65172-3.
Varga MG, Epplein M. Helicobacter Pylori-Mediated Carcinogenesis. In: Encyclopedia of Cancer Third Edition Volumes 1 3. 2018. p. V2-197.
Varga, M. G., and M. Epplein. “Helicobacter Pylori-Mediated Carcinogenesis.” Encyclopedia of Cancer Third Edition Volumes 1 3, vol. 2, 2018, pp. V2-197. Scopus, doi:10.1016/B978-0-12-801238-3.65172-3.
Varga MG, Epplein M. Helicobacter Pylori-Mediated Carcinogenesis. Encyclopedia of Cancer Third Edition Volumes 1 3. 2018. p. V2-197.

DOI

Publication Date

January 1, 2018

Volume

2

Start / End Page

V2 / 197