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Methadone Analgesia During Awake Craniotomy for a Patient With Chronic Pain on Buprenorphine: A Case Report.

Publication ,  Journal Article
Isham, DC; Sytsma, TM; Patel, AP; Ramaiah, VK
Published in: A A Pract
April 1, 2025

The resection of brain tumors requires careful surgical and anesthetic planning to preserve essential motor, cognitive, and sensory cortical regions. An awake craniotomy with stereotactic brain mapping is frequently performed to protect these areas, requiring patients to be conscious enough for functional and neurocognitive testing. Patients on long-term opioids for chronic pain present unique anesthetic challenges, requiring anesthesiologists to balance providing adequate analgesia with maintaining adequate responsiveness. This case report illustrates the successful use of methadone in the anesthetic management of a patient with chronic pain on transdermal buprenorphine who underwent an awake craniotomy with an asleep-awake technique.

Duke Scholars

Published In

A A Pract

DOI

EISSN

2575-3126

Publication Date

April 1, 2025

Volume

19

Issue

4

Start / End Page

e01957

Location

United States

Related Subject Headings

  • Wakefulness
  • Methadone
  • Humans
  • Craniotomy
  • Chronic Pain
  • Buprenorphine
  • Brain Neoplasms
  • Analgesics, Opioid
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Isham, D. C., Sytsma, T. M., Patel, A. P., & Ramaiah, V. K. (2025). Methadone Analgesia During Awake Craniotomy for a Patient With Chronic Pain on Buprenorphine: A Case Report. A A Pract, 19(4), e01957. https://doi.org/10.1213/XAA.0000000000001957
Isham, Danielle C., Trevor M. Sytsma, Anoop P. Patel, and Vijay K. Ramaiah. “Methadone Analgesia During Awake Craniotomy for a Patient With Chronic Pain on Buprenorphine: A Case Report.A A Pract 19, no. 4 (April 1, 2025): e01957. https://doi.org/10.1213/XAA.0000000000001957.
Isham DC, Sytsma TM, Patel AP, Ramaiah VK. Methadone Analgesia During Awake Craniotomy for a Patient With Chronic Pain on Buprenorphine: A Case Report. A A Pract. 2025 Apr 1;19(4):e01957.
Isham, Danielle C., et al. “Methadone Analgesia During Awake Craniotomy for a Patient With Chronic Pain on Buprenorphine: A Case Report.A A Pract, vol. 19, no. 4, Apr. 2025, p. e01957. Pubmed, doi:10.1213/XAA.0000000000001957.
Isham DC, Sytsma TM, Patel AP, Ramaiah VK. Methadone Analgesia During Awake Craniotomy for a Patient With Chronic Pain on Buprenorphine: A Case Report. A A Pract. 2025 Apr 1;19(4):e01957.

Published In

A A Pract

DOI

EISSN

2575-3126

Publication Date

April 1, 2025

Volume

19

Issue

4

Start / End Page

e01957

Location

United States

Related Subject Headings

  • Wakefulness
  • Methadone
  • Humans
  • Craniotomy
  • Chronic Pain
  • Buprenorphine
  • Brain Neoplasms
  • Analgesics, Opioid