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Decentralization of snakebite antivenom treatment to indigenous community health centers in the Brazilian Amazon: From demand to the first treatment (the SAVING Program).

Publication ,  Journal Article
Seabra de Farias, A; Serrão-Pinto, T; Cardoso, D; Augusto Guimarães Figueira, E; Almeida-Val, F; Amorim Ramos, T; Dourado, FS; Montebello, L ...
Published in: PLoS Negl Trop Dis
April 2025

Brazilian antivenoms have excellent efficacy in recovering venom-induced coagulopathy, in addition to having a good safety profile with only 10% of patients experiencing a mild reaction such as urticaria or pruritus. More than 3.5 hundred thousand snakebite antivenom vials are produced per year, and all the batches are acquired by the Ministry of Health and distributed free of charge to 2,200 hospitals across the national territory. However, these health facilities are unevenly distributed across the territory, so that the distance a patient needs to travel to receive care is much greater in the Amazon region in comparison to the extra-Amazonia region, leading to a huge access barrier in this region. The lack of access to healthcare facilities for snakebite patients may be greater than 30% in some regions of the Amazonia. The decentralization of SBE treatment with antivenoms to the scope of indigenous community health centers requires the discussion of proper organizational designs and arrangements of practices based on the user needs, singularities of the territory, and the clinical reality of the indigenous populations. In this report, we describe a successful experience of decentralization of antivenom treatment for an indigenous health unit in the Brazilian Amazon, which provides a platform to improve the lives of SBE patients at risk of this life-threatening condition. In this work, we report the experience in the development and implementation of a program to decentralize antivenom treatment for indigenous communities, which represents a significant change in the national policy for snakebite control, with a potential impact on reducing morbidity and mortality from this health problem. In the next steps, SAVING Program will be evaluated through mixed-method studies in regards team and community's experience within the program, aiming to identify barriers, perceptions about the implementation process, and facilitators for the maintenance/sustainability.

Duke Scholars

Published In

PLoS Negl Trop Dis

DOI

EISSN

1935-2735

Publication Date

April 2025

Volume

19

Issue

4

Start / End Page

e0013011

Location

United States

Related Subject Headings

  • Tropical Medicine
  • Snake Bites
  • Male
  • Humans
  • Health Services Accessibility
  • Female
  • Community Health Centers
  • Brazil
  • Antivenins
  • Adult
 

Citation

APA
Chicago
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Seabra de Farias, A., Serrão-Pinto, T., Cardoso, D., Augusto Guimarães Figueira, E., Almeida-Val, F., Amorim Ramos, T., … Monteiro, W. (2025). Decentralization of snakebite antivenom treatment to indigenous community health centers in the Brazilian Amazon: From demand to the first treatment (the SAVING Program). PLoS Negl Trop Dis, 19(4), e0013011. https://doi.org/10.1371/journal.pntd.0013011
Seabra de Farias, Altair, Thiago Serrão-Pinto, Deugles Cardoso, Elder Augusto Guimarães Figueira, Fernando Almeida-Val, Tatyana Amorim Ramos, Flávio Santos Dourado, et al. “Decentralization of snakebite antivenom treatment to indigenous community health centers in the Brazilian Amazon: From demand to the first treatment (the SAVING Program).PLoS Negl Trop Dis 19, no. 4 (April 2025): e0013011. https://doi.org/10.1371/journal.pntd.0013011.
Seabra de Farias A, Serrão-Pinto T, Cardoso D, Augusto Guimarães Figueira E, Almeida-Val F, Amorim Ramos T, et al. Decentralization of snakebite antivenom treatment to indigenous community health centers in the Brazilian Amazon: From demand to the first treatment (the SAVING Program). PLoS Negl Trop Dis. 2025 Apr;19(4):e0013011.
Seabra de Farias, Altair, et al. “Decentralization of snakebite antivenom treatment to indigenous community health centers in the Brazilian Amazon: From demand to the first treatment (the SAVING Program).PLoS Negl Trop Dis, vol. 19, no. 4, Apr. 2025, p. e0013011. Pubmed, doi:10.1371/journal.pntd.0013011.
Seabra de Farias A, Serrão-Pinto T, Cardoso D, Augusto Guimarães Figueira E, Almeida-Val F, Amorim Ramos T, Dourado FS, Ferreira de Lima-Junior FE, Montebello L, Rodrigues Gomes Filho M, da Silva Ipuchima L, Ferreira de Souza N, da Costa Arévalo M, Lacerda M, Azevedo Machado V, Murta F, Gerardo C, Vissoci J, Hui Wen F, Sachett J, Monteiro W. Decentralization of snakebite antivenom treatment to indigenous community health centers in the Brazilian Amazon: From demand to the first treatment (the SAVING Program). PLoS Negl Trop Dis. 2025 Apr;19(4):e0013011.

Published In

PLoS Negl Trop Dis

DOI

EISSN

1935-2735

Publication Date

April 2025

Volume

19

Issue

4

Start / End Page

e0013011

Location

United States

Related Subject Headings

  • Tropical Medicine
  • Snake Bites
  • Male
  • Humans
  • Health Services Accessibility
  • Female
  • Community Health Centers
  • Brazil
  • Antivenins
  • Adult