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3D rotational shear wave elasticity imaging (3D-RSWEI) in anisotropic lattice phantoms.

Publication ,  Journal Article
Srinivasan, S; Eckstein, KN; Yoon, D; Rouze, NC; Bock, KD; Villacis, E; Bayly, PV; Nightingale, KR
Published in: Journal of the mechanical behavior of biomedical materials
October 2025

We present ultrasonic 3D rotational shear wave elasticity imaging (3D-RSWEI) characterization of anisotropic 3D-printed hydrogel lattice phantoms that were originally developed for magnetic resonance elastography (MRE) applications. Shear wave speeds versus rotational angle were measured for two 3D-printed hydrogel lattices while submerged in water and after embedding in different stiffnesses of isotropic poly-vinyl alcohol (PVA). Shear wave propagation in the lattices was anisotropic, with faster wave speeds parallel to the scaling direction of the lattices. We observed that shear wave speeds and shear anisotropy decreased when the lattices were embedded in PVA versus submerged in water. Shear wave dispersion was observed in the lattice+PVA phantoms, with greater dispersion in the direction parallel to the scaling direction versus perpendicular. Dynamic shear testing results of the lattice+PVA phantoms were compared to 3D-RSWEI characterization with differences of 8.4% and 24.1% for propagation parallel and perpendicular to the scaling direction. These results demonstrate the feasibility of ultrasonic SWEI characterization of novel anisotropic MRE lattice phantoms.

Duke Scholars

Published In

Journal of the mechanical behavior of biomedical materials

DOI

EISSN

1878-0180

ISSN

1751-6161

Publication Date

October 2025

Volume

170

Start / End Page

107048

Related Subject Headings

  • Rotation
  • Printing, Three-Dimensional
  • Polyvinyl Alcohol
  • Phantoms, Imaging
  • Imaging, Three-Dimensional
  • Elasticity Imaging Techniques
  • Biomedical Engineering
  • Anisotropy
  • 4017 Mechanical engineering
  • 4016 Materials engineering
 

Citation

APA
Chicago
ICMJE
MLA
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Srinivasan, S., Eckstein, K. N., Yoon, D., Rouze, N. C., Bock, K. D., Villacis, E., … Nightingale, K. R. (2025). 3D rotational shear wave elasticity imaging (3D-RSWEI) in anisotropic lattice phantoms. Journal of the Mechanical Behavior of Biomedical Materials, 170, 107048. https://doi.org/10.1016/j.jmbbm.2025.107048
Srinivasan, Shruthi, Kevin N. Eckstein, Daniel Yoon, Ned C. Rouze, Kaden D. Bock, Estela Villacis, Philip V. Bayly, and Kathryn R. Nightingale. “3D rotational shear wave elasticity imaging (3D-RSWEI) in anisotropic lattice phantoms.Journal of the Mechanical Behavior of Biomedical Materials 170 (October 2025): 107048. https://doi.org/10.1016/j.jmbbm.2025.107048.
Srinivasan S, Eckstein KN, Yoon D, Rouze NC, Bock KD, Villacis E, et al. 3D rotational shear wave elasticity imaging (3D-RSWEI) in anisotropic lattice phantoms. Journal of the mechanical behavior of biomedical materials. 2025 Oct;170:107048.
Srinivasan, Shruthi, et al. “3D rotational shear wave elasticity imaging (3D-RSWEI) in anisotropic lattice phantoms.Journal of the Mechanical Behavior of Biomedical Materials, vol. 170, Oct. 2025, p. 107048. Epmc, doi:10.1016/j.jmbbm.2025.107048.
Srinivasan S, Eckstein KN, Yoon D, Rouze NC, Bock KD, Villacis E, Bayly PV, Nightingale KR. 3D rotational shear wave elasticity imaging (3D-RSWEI) in anisotropic lattice phantoms. Journal of the mechanical behavior of biomedical materials. 2025 Oct;170:107048.
Journal cover image

Published In

Journal of the mechanical behavior of biomedical materials

DOI

EISSN

1878-0180

ISSN

1751-6161

Publication Date

October 2025

Volume

170

Start / End Page

107048

Related Subject Headings

  • Rotation
  • Printing, Three-Dimensional
  • Polyvinyl Alcohol
  • Phantoms, Imaging
  • Imaging, Three-Dimensional
  • Elasticity Imaging Techniques
  • Biomedical Engineering
  • Anisotropy
  • 4017 Mechanical engineering
  • 4016 Materials engineering