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Bioethical Considerations of Deploying Artificial Intelligence in Clinical Orthopedic Settings: A Narrative Review.

Journal articles  - Journal Article, Review
Kiwinda, LV; Kocher, SD; Bryniarski, AR; Pean, CA
Published in: HSS J
August 2025

Artificial intelligence (AI) has emerged in orthopedics with the potential to improve diagnostic accuracy, optimize surgical workflows, and support personalized care. We conducted a narrative review exploring the bioethical considerations of AI use in the orthopedic clinical setting, focusing on 4 core principles-autonomy, beneficence, nonmaleficence, and justice-to provide orthopedists with a practical framework for AI's implementation. We utilized the Preferred Reporting Items for Systematic Reviews and Meta-Analyses framework to conduct a comprehensive PubMed search; 89 articles were evaluated and 23 met our inclusion criteria. Across these studies, bioethical considerations for the clinical implementation of AI tools consistently emerged, most commonly concerning privacy, bias, transparency, informed consent, and regulation. We offer recommendations for strengthening privacy safeguards, adopting bias mitigation strategies, improving transparency through explainable AI tools, and establishing clear regulatory frameworks with lifecycle evaluation.

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Published In

HSS J

DOI

ISSN

1556-3316

Publication Date

August 2025

Volume

21

Issue

3

Start / End Page

274 / 282

Location

United States

Related Subject Headings

  • Orthopedics
  • 3202 Clinical sciences
 

Citation

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Chicago
ICMJE
MLA
NLM
Kiwinda, L. V., Kocher, S. D., Bryniarski, A. R., & Pean, C. A. (2025). Bioethical Considerations of Deploying Artificial Intelligence in Clinical Orthopedic Settings: A Narrative Review. HSS J, 21(3), 274–282. https://doi.org/10.1177/15563316251340303
Kiwinda, Lulla V., Sophia D. Kocher, Anna R. Bryniarski, and Christian A. Pean. “Bioethical Considerations of Deploying Artificial Intelligence in Clinical Orthopedic Settings: A Narrative Review.HSS J 21, no. 3 (August 2025): 274–82. https://doi.org/10.1177/15563316251340303.
Kiwinda LV, Kocher SD, Bryniarski AR, Pean CA. Bioethical Considerations of Deploying Artificial Intelligence in Clinical Orthopedic Settings: A Narrative Review. HSS J. 2025 Aug;21(3):274–82.
Kiwinda, Lulla V., et al. “Bioethical Considerations of Deploying Artificial Intelligence in Clinical Orthopedic Settings: A Narrative Review.HSS J, vol. 21, no. 3, Aug. 2025, pp. 274–82. Pubmed, doi:10.1177/15563316251340303.
Kiwinda LV, Kocher SD, Bryniarski AR, Pean CA. Bioethical Considerations of Deploying Artificial Intelligence in Clinical Orthopedic Settings: A Narrative Review. HSS J. 2025 Aug;21(3):274–282.
Journal cover image

Published In

HSS J

DOI

ISSN

1556-3316

Publication Date

August 2025

Volume

21

Issue

3

Start / End Page

274 / 282

Location

United States

Related Subject Headings

  • Orthopedics
  • 3202 Clinical sciences