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Green Revolution DELLA Proteins: Functional Analysis and Regulatory Mechanisms.

Publication ,  Journal Article
Alabadí, D; Sun, T-P
Published in: Annual review of plant biology
May 2025

The DELLA genes, also referred to as Green Revolution genes, encode conserved master growth regulators in plants. The nuclear-localized DELLA proteins are transcription regulators that interact with hundreds of transcription factors and other transcription regulators. They not only function as gibberellin signaling repressors in vascular plants but also play a central role in coordinating diverse signaling pathways in response to both internal hormonal signals and external cues (e.g., light and nutrient conditions, biotic and abiotic stresses). Through a combination of genetic, genomic, biochemical, and structural studies, significant advances have been made in understanding both the functional domains and motifs within DELLAs and the molecular mechanisms underlying their function. Here, we highlight new insights into the molecular workings of DELLA proteins, including an evolutionary perspective.

Duke Scholars

Published In

Annual review of plant biology

DOI

EISSN

1545-2123

ISSN

1543-5008

Publication Date

May 2025

Volume

76

Issue

1

Start / End Page

373 / 400

Related Subject Headings

  • Transcription Factors
  • Signal Transduction
  • Plants
  • Plant Proteins
  • Plant Growth Regulators
  • Plant Biology & Botany
  • Gibberellins
  • Gene Expression Regulation, Plant
  • Arabidopsis Proteins
  • 3108 Plant biology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Alabadí, D., & Sun, T.-P. (2025). Green Revolution DELLA Proteins: Functional Analysis and Regulatory Mechanisms. Annual Review of Plant Biology, 76(1), 373–400. https://doi.org/10.1146/annurev-arplant-053124-050732
Alabadí, David, and Tai-Ping Sun. “Green Revolution DELLA Proteins: Functional Analysis and Regulatory Mechanisms.Annual Review of Plant Biology 76, no. 1 (May 2025): 373–400. https://doi.org/10.1146/annurev-arplant-053124-050732.
Alabadí D, Sun T-P. Green Revolution DELLA Proteins: Functional Analysis and Regulatory Mechanisms. Annual review of plant biology. 2025 May;76(1):373–400.
Alabadí, David, and Tai-Ping Sun. “Green Revolution DELLA Proteins: Functional Analysis and Regulatory Mechanisms.Annual Review of Plant Biology, vol. 76, no. 1, May 2025, pp. 373–400. Epmc, doi:10.1146/annurev-arplant-053124-050732.
Alabadí D, Sun T-P. Green Revolution DELLA Proteins: Functional Analysis and Regulatory Mechanisms. Annual review of plant biology. 2025 May;76(1):373–400.

Published In

Annual review of plant biology

DOI

EISSN

1545-2123

ISSN

1543-5008

Publication Date

May 2025

Volume

76

Issue

1

Start / End Page

373 / 400

Related Subject Headings

  • Transcription Factors
  • Signal Transduction
  • Plants
  • Plant Proteins
  • Plant Growth Regulators
  • Plant Biology & Botany
  • Gibberellins
  • Gene Expression Regulation, Plant
  • Arabidopsis Proteins
  • 3108 Plant biology