Transplant-Related and Metastatic Malignancies
The advances in surgical techniques and the introduction of more effective and less toxic immunosuppression regimens have resulted in increased rate of successful transplantation with extended survival of the recipients. Histologic assessment continues to play an essential role in the diagnosis of complications secondary to therapy in this population. In this chapter we discuss the most common cutaneous diseases that may result from hematopoietic stem cell transplantation. Metastatic diseases involving the skin are also discussed. Introduction: Transplantation of hematopoietic stem cells has revolutionized the type of care that can be provided for patients with multiple neoplastic and nonneoplastic processes. However, transplantation carries a myriad of risks for multiple disorders that can affect almost any organ system. In this chapter we discuss the most common cutaneous diseases that may result from hematopoietic stem cell transplantation. Additionally, this chapter covers metastatic malignancies involving the skin.
