2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on Histoplasmosis: Treatment of Asymptomatic Histoplasma Pulmonary Nodules (Histoplasmomas) in Adults, Children, and Pregnant People.
Publication
, Journal Article
Baddley, JW; Wolf, J; Ardura, MI; Badreldin, N; Bahr, NC; Bloch, K; Kauffman, CA; Lentz, RJ; Miller, RA; Mocherla, S; Pappas, P; Saccente, M ...
Published in: Clin Infect Dis
January 16, 2026
This paper is part of a larger clinical practice guideline on the management of histoplasmosis in adults, children, and pregnant people, developed by the Infectious Diseases Society of America. In this paper, the panel provides a recommendation for treatment of asymptomatic pulmonary nodules. The panel's recommendation is based upon evidence derived from systematic literature reviews and adheres to a standardized methodology for rating the certainty of evidence and strength of recommendation according to the GRADE (Grading of Recommendations Assessment, Development, and Evaluation) approach.
Duke Scholars
Published In
Clin Infect Dis
DOI
EISSN
1537-6591
Publication Date
January 16, 2026
Volume
81
Issue
Supplement_3
Start / End Page
i33 / i38
Location
United States
Related Subject Headings
- Pregnancy Complications, Infectious
- Pregnancy
- Microbiology
- Humans
- Histoplasmosis
- Histoplasma
- Female
- Child
- Antifungal Agents
- Adult
Citation
APA
Chicago
ICMJE
MLA
NLM
Baddley, J. W., Wolf, J., Ardura, M. I., Badreldin, N., Bahr, N. C., Bloch, K., … Arnold, S. R. (2026). 2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on Histoplasmosis: Treatment of Asymptomatic Histoplasma Pulmonary Nodules (Histoplasmomas) in Adults, Children, and Pregnant People. Clin Infect Dis, 81(Supplement_3), i33–i38. https://doi.org/10.1093/cid/ciaf257
Baddley, John W., Joshua Wolf, Monica I. Ardura, Nevert Badreldin, Nathan C. Bahr, Karen Bloch, Carol A. Kauffman, et al. “2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on Histoplasmosis: Treatment of Asymptomatic Histoplasma Pulmonary Nodules (Histoplasmomas) in Adults, Children, and Pregnant People.” Clin Infect Dis 81, no. Supplement_3 (January 16, 2026): i33–38. https://doi.org/10.1093/cid/ciaf257.
Baddley JW, Wolf J, Ardura MI, Badreldin N, Bahr NC, Bloch K, et al. 2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on Histoplasmosis: Treatment of Asymptomatic Histoplasma Pulmonary Nodules (Histoplasmomas) in Adults, Children, and Pregnant People. Clin Infect Dis. 2026 Jan 16;81(Supplement_3):i33–8.
Baddley, John W., et al. “2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on Histoplasmosis: Treatment of Asymptomatic Histoplasma Pulmonary Nodules (Histoplasmomas) in Adults, Children, and Pregnant People.” Clin Infect Dis, vol. 81, no. Supplement_3, Jan. 2026, pp. i33–38. Pubmed, doi:10.1093/cid/ciaf257.
Baddley JW, Wolf J, Ardura MI, Badreldin N, Bahr NC, Bloch K, Kauffman CA, Lentz RJ, Miller RA, Mocherla S, Pappas P, Saccente M, Schwartz I, Stover KR, Wiederhold NP, Loveless J, Spec A, Arnold SR. 2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on Histoplasmosis: Treatment of Asymptomatic Histoplasma Pulmonary Nodules (Histoplasmomas) in Adults, Children, and Pregnant People. Clin Infect Dis. 2026 Jan 16;81(Supplement_3):i33–i38.
Published In
Clin Infect Dis
DOI
EISSN
1537-6591
Publication Date
January 16, 2026
Volume
81
Issue
Supplement_3
Start / End Page
i33 / i38
Location
United States
Related Subject Headings
- Pregnancy Complications, Infectious
- Pregnancy
- Microbiology
- Humans
- Histoplasmosis
- Histoplasma
- Female
- Child
- Antifungal Agents
- Adult