Safety and secondary pharmacology: successes, threats, challenges and opportunities.
Publication
, Journal Article
Valentin, J-P; Hammond, T
Published in: J Pharmacol Toxicol Methods
2008
This review summarises the lecture of Dr Tim Hammond, recipient of the Distinguished Service Award of the Safety Pharmacology Society, given on 20 September 2007 in Edinburgh. The lecture discussed the rationale behind the need for optimal non-clinical Safety and Secondary Pharmacology testing; the evolution of Safety and Secondary Pharmacology over the last decade; its impact on drug discovery and development; the value of adopting an integrated risk assessment approach; the translation of non-clinical findings to humans and finally the future challenges and opportunities facing these disciplines.
Duke Scholars
Published In
J Pharmacol Toxicol Methods
DOI
EISSN
1873-488X
Publication Date
2008
Volume
58
Issue
2
Start / End Page
77 / 87
Location
United States
Related Subject Headings
- Toxicity Tests
- Rats
- Pharmacology & Pharmacy
- Pharmacology
- Humans
- Drug-Related Side Effects and Adverse Reactions
- Animals
- 3214 Pharmacology and pharmaceutical sciences
- 1115 Pharmacology and Pharmaceutical Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Valentin, J.-P., & Hammond, T. (2008). Safety and secondary pharmacology: successes, threats, challenges and opportunities. J Pharmacol Toxicol Methods, 58(2), 77–87. https://doi.org/10.1016/j.vascn.2008.05.007
Valentin, Jean-Pierre, and Tim Hammond. “Safety and secondary pharmacology: successes, threats, challenges and opportunities.” J Pharmacol Toxicol Methods 58, no. 2 (2008): 77–87. https://doi.org/10.1016/j.vascn.2008.05.007.
Valentin J-P, Hammond T. Safety and secondary pharmacology: successes, threats, challenges and opportunities. J Pharmacol Toxicol Methods. 2008;58(2):77–87.
Valentin, Jean-Pierre, and Tim Hammond. “Safety and secondary pharmacology: successes, threats, challenges and opportunities.” J Pharmacol Toxicol Methods, vol. 58, no. 2, 2008, pp. 77–87. Pubmed, doi:10.1016/j.vascn.2008.05.007.
Valentin J-P, Hammond T. Safety and secondary pharmacology: successes, threats, challenges and opportunities. J Pharmacol Toxicol Methods. 2008;58(2):77–87.
Published In
J Pharmacol Toxicol Methods
DOI
EISSN
1873-488X
Publication Date
2008
Volume
58
Issue
2
Start / End Page
77 / 87
Location
United States
Related Subject Headings
- Toxicity Tests
- Rats
- Pharmacology & Pharmacy
- Pharmacology
- Humans
- Drug-Related Side Effects and Adverse Reactions
- Animals
- 3214 Pharmacology and pharmaceutical sciences
- 1115 Pharmacology and Pharmaceutical Sciences