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Enhancing the Characterization of Dural Tears on Photon-Counting CT Myelography: An Analysis of Reconstruction Techniques.

Publication ,  Journal Article
Madhavan, AA; Kranz, PG; Kodet, ML; Yu, L; Zhou, Z; Amrhein, TJ
Published in: AJNR Am J Neuroradiol
February 3, 2026

Photon-counting detector CT myelography is an effective technique for the localization of spinal CSF leaks. The initial studies describing this technique used a relatively smooth Br56 kernel. However, subsequent studies have demonstrated that the use of the sharpest quantitative kernel on photon-counting CT (Qr89), particularly when denoised with techniques such as quantum iterative reconstruction or convolutional neural networks, enhances the detection of CSF-venous fistulas. In this clinical report, we sought to determine whether the Qr89 kernel has utility in patients with dural tears, the other main type of spinal CSF leak. We performed a retrospective review of patients with dural tears diagnosed on photon-counting CT myelography, comparing Br56, Qr89 denoised with quantum iterative reconstruction, and Qr89 denoised with a trained convolutional neural network. We specifically assessed spatial resolution, noise level, and diagnostic confidence in 8 such cases, finding that the sharper Qr89 kernel outperformed the smoother Br56 kernel. This finding was particularly true when Qr89 was denoised using a convolutional neural network. Furthermore, in 2 cases, the dural tear was only seen on the Qr89 reconstructions and missed on the Br56 kernel. Overall, our study demonstrates the potential value of further optimizing postprocessing techniques for photon-counting CT myelography aimed at localizing dural tears.

Duke Scholars

Published In

AJNR Am J Neuroradiol

DOI

EISSN

1936-959X

Publication Date

February 3, 2026

Volume

47

Issue

2

Start / End Page

532 / 536

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Retrospective Studies
  • Radiographic Image Interpretation, Computer-Assisted
  • Nuclear Medicine & Medical Imaging
  • Neural Networks, Computer
  • Myelography
  • Middle Aged
  • Male
  • Humans
  • Female
 

Citation

APA
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ICMJE
MLA
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Madhavan, A. A., Kranz, P. G., Kodet, M. L., Yu, L., Zhou, Z., & Amrhein, T. J. (2026). Enhancing the Characterization of Dural Tears on Photon-Counting CT Myelography: An Analysis of Reconstruction Techniques. AJNR Am J Neuroradiol, 47(2), 532–536. https://doi.org/10.3174/ajnr.A8938
Madhavan, Ajay A., Peter G. Kranz, Michelle L. Kodet, Lifeng Yu, Zhongxing Zhou, and Timothy J. Amrhein. “Enhancing the Characterization of Dural Tears on Photon-Counting CT Myelography: An Analysis of Reconstruction Techniques.AJNR Am J Neuroradiol 47, no. 2 (February 3, 2026): 532–36. https://doi.org/10.3174/ajnr.A8938.
Madhavan AA, Kranz PG, Kodet ML, Yu L, Zhou Z, Amrhein TJ. Enhancing the Characterization of Dural Tears on Photon-Counting CT Myelography: An Analysis of Reconstruction Techniques. AJNR Am J Neuroradiol. 2026 Feb 3;47(2):532–6.
Madhavan, Ajay A., et al. “Enhancing the Characterization of Dural Tears on Photon-Counting CT Myelography: An Analysis of Reconstruction Techniques.AJNR Am J Neuroradiol, vol. 47, no. 2, Feb. 2026, pp. 532–36. Pubmed, doi:10.3174/ajnr.A8938.
Madhavan AA, Kranz PG, Kodet ML, Yu L, Zhou Z, Amrhein TJ. Enhancing the Characterization of Dural Tears on Photon-Counting CT Myelography: An Analysis of Reconstruction Techniques. AJNR Am J Neuroradiol. 2026 Feb 3;47(2):532–536.

Published In

AJNR Am J Neuroradiol

DOI

EISSN

1936-959X

Publication Date

February 3, 2026

Volume

47

Issue

2

Start / End Page

532 / 536

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Retrospective Studies
  • Radiographic Image Interpretation, Computer-Assisted
  • Nuclear Medicine & Medical Imaging
  • Neural Networks, Computer
  • Myelography
  • Middle Aged
  • Male
  • Humans
  • Female