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Process Variation in Liver, Kidney, and Pancreas Transplantation: A Multicenter Evaluation From the Consortium for the Holistic Assessment of Risk in Transplant.

Publication ,  Journal Article
Strauss, AT; Caicedo, JC; Welsh, W; Reed, RD; Gordon, EJ; Taber, D; Ng, YH; Ross-Driscoll, K; Schold, JD; Serper, M; Olson, A; Harding, JL ...
Published in: Transplant Direct
September 2025

BACKGROUND: Transplant center processes for determining candidacy are complex, poorly documented, ambiguous, and variable across centers. Opaque and nonstandardized transplant processes can compromise data collection and lead to inconsistent outcomes. METHODS: To understand process variation and data quality in transplantation, we surveyed 8 abdominal transplant centers in an existing research consortium about their processes of care for liver, kidney, and pancreas transplants. We used the Systems Engineering Initiative for Patient Safety model to identify variation related to people, tasks, tools, environment, and processes. RESULTS: Centers varied in their processes across phases of transplant care, including screening referral, waitlist maintenance, and posttransplant follow-up. Regarding referrals, transplant centers chose their locations for outreach to and education for referring providers based on historical density or by request (63%). Additionally, screening of referred patients for transplant evaluation varied across centers related to screening method, screening timing/attempts, and who determines eligibility. For patients declined for listing, only 25% of centers had a formal appeal process (liver only), and most centers had either an informal appeal process (liver: 50%, kidney and pancreas: 87.5%) or none (liver: 25%, kidney and pancreas: 12.5%). CONCLUSIONS: In light of increased national attention to improving data collection, processes of care, and workforce efficiency, our findings provide insight into processes that may inform effective transplant practices and identify targets for future interventions.

Duke Scholars

Published In

Transplant Direct

DOI

ISSN

2373-8731

Publication Date

September 2025

Volume

11

Issue

9

Start / End Page

e1850

Location

United States

Related Subject Headings

  • 3204 Immunology
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology
 

Citation

APA
Chicago
ICMJE
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Strauss, A. T., Caicedo, J. C., Welsh, W., Reed, R. D., Gordon, E. J., Taber, D., … McElroy, L. M. (2025). Process Variation in Liver, Kidney, and Pancreas Transplantation: A Multicenter Evaluation From the Consortium for the Holistic Assessment of Risk in Transplant. Transplant Direct, 11(9), e1850. https://doi.org/10.1097/TXD.0000000000001850
Strauss, Alexandra T., Juan Carlos Caicedo, Whitney Welsh, Rhiannon Deierhoi Reed, Elisa J. Gordon, David Taber, Yue Harn Ng, et al. “Process Variation in Liver, Kidney, and Pancreas Transplantation: A Multicenter Evaluation From the Consortium for the Holistic Assessment of Risk in Transplant.Transplant Direct 11, no. 9 (September 2025): e1850. https://doi.org/10.1097/TXD.0000000000001850.
Strauss AT, Caicedo JC, Welsh W, Reed RD, Gordon EJ, Taber D, et al. Process Variation in Liver, Kidney, and Pancreas Transplantation: A Multicenter Evaluation From the Consortium for the Holistic Assessment of Risk in Transplant. Transplant Direct. 2025 Sep;11(9):e1850.
Strauss, Alexandra T., et al. “Process Variation in Liver, Kidney, and Pancreas Transplantation: A Multicenter Evaluation From the Consortium for the Holistic Assessment of Risk in Transplant.Transplant Direct, vol. 11, no. 9, Sept. 2025, p. e1850. Pubmed, doi:10.1097/TXD.0000000000001850.
Strauss AT, Caicedo JC, Welsh W, Reed RD, Gordon EJ, Taber D, Ng YH, Ross-Driscoll K, Schold JD, Serper M, Olson A, Harding JL, Adams A, Kirk AD, McElroy LM. Process Variation in Liver, Kidney, and Pancreas Transplantation: A Multicenter Evaluation From the Consortium for the Holistic Assessment of Risk in Transplant. Transplant Direct. 2025 Sep;11(9):e1850.

Published In

Transplant Direct

DOI

ISSN

2373-8731

Publication Date

September 2025

Volume

11

Issue

9

Start / End Page

e1850

Location

United States

Related Subject Headings

  • 3204 Immunology
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology