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The assessment and management of patients with type 2 myocardial infarction: an international Delphi study.

Publication ,  Journal Article
Taggart, C; Ferry, AV; Chapman, AR; Schulberg, SD; Bularga, A; Wereski, R; Boeddinghaus, J; Kimenai, DM; Lowry, MTH; Chew, DP; Cullen, L ...
Published in: Eur Heart J Qual Care Clin Outcomes
December 19, 2025

AIMS: Type 2 myocardial infarction due to myocardial oxygen supply-demand imbalance is associated with poor outcomes. There are no guidelines to inform care for these patients. The consensus on the assessment and management of type 2 myocardial infarction is gained. METHODS AND RESULTS: An international e-Delphi study including experts in type 2 myocardial infarction identified through systematic review was conducted. Participants were asked to describe their approach to (i) definition and diagnosis, (ii) risk stratification, (iii) assessment of coronary artery disease and cardiac function, (iv) specialty management, (v) treatment and secondary prevention, and (vi) communication and rehabilitation. Statements generated in round one were circulated, with consensus defined a priori as ≥70% agreement on a 5-point Likert scale. Where no consensus was reached, statements were amended and recirculated for a final round. The response rate was 56% (38/68), 54% (37/68), and 72% (49/68) in the first, second, and third rounds, respectively. Following the first round, 67 unique statements were generated across six domains. Overall, consensus was achieved on 64% (43/67) of statements. Consensus was achieved for 42% (5/12) of statements on the diagnosis of type 2 myocardial infarction, 75% (3/4) on risk stratification, 50% (9/18) on the assessment of coronary artery disease and cardiac function, 60% (6/10), on specialty management, 100% (9/9) on treatment and secondary prevention, and 79% (11/15) on communication and rehabilitation. CONCLUSION: Consensus was obtained across a number of domains for the assessment and management of patients with type 2 myocardial infarction. However, there was limited agreement amongst experts on the diagnostic criteria, which may benefit from refinement.

Duke Scholars

Published In

Eur Heart J Qual Care Clin Outcomes

DOI

EISSN

2058-1742

Publication Date

December 19, 2025

Volume

11

Issue

8

Start / End Page

1421 / 1430

Location

England

Related Subject Headings

  • Secondary Prevention
  • Risk Assessment
  • Myocardial Infarction
  • Humans
  • Disease Management
  • Delphi Technique
  • Consensus
  • 4206 Public health
  • 3201 Cardiovascular medicine and haematology
 

Citation

APA
Chicago
ICMJE
MLA
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Taggart, C., Ferry, A. V., Chapman, A. R., Schulberg, S. D., Bularga, A., Wereski, R., … Mills, N. L. (2025). The assessment and management of patients with type 2 myocardial infarction: an international Delphi study. Eur Heart J Qual Care Clin Outcomes, 11(8), 1421–1430. https://doi.org/10.1093/ehjqcco/qcaf069
Taggart, Caelan, Amy V. Ferry, Andrew R. Chapman, Stacey D. Schulberg, Anda Bularga, Ryan Wereski, Jasper Boeddinghaus, et al. “The assessment and management of patients with type 2 myocardial infarction: an international Delphi study.Eur Heart J Qual Care Clin Outcomes 11, no. 8 (December 19, 2025): 1421–30. https://doi.org/10.1093/ehjqcco/qcaf069.
Taggart C, Ferry AV, Chapman AR, Schulberg SD, Bularga A, Wereski R, et al. The assessment and management of patients with type 2 myocardial infarction: an international Delphi study. Eur Heart J Qual Care Clin Outcomes. 2025 Dec 19;11(8):1421–30.
Taggart, Caelan, et al. “The assessment and management of patients with type 2 myocardial infarction: an international Delphi study.Eur Heart J Qual Care Clin Outcomes, vol. 11, no. 8, Dec. 2025, pp. 1421–30. Pubmed, doi:10.1093/ehjqcco/qcaf069.
Taggart C, Ferry AV, Chapman AR, Schulberg SD, Bularga A, Wereski R, Boeddinghaus J, Kimenai DM, Lowry MTH, Chew DP, Cullen L, Daniels LB, Devereaux PJ, French J, Gaggin HK, Huynh T, Jacquin L, Jaffe AS, Jernberg T, Koronowski R, McCarthy C, McCord J, Mamas MA, Mickley H, Morrow DA, Mueller C, Newby LK, Parsonage W, Raphael CE, Smer A, Smith SW, Sandoval Y, Smilowitz NR, White H, Eggers KM, Lindahl B, Thygesen K, Mills NL. The assessment and management of patients with type 2 myocardial infarction: an international Delphi study. Eur Heart J Qual Care Clin Outcomes. 2025 Dec 19;11(8):1421–1430.
Journal cover image

Published In

Eur Heart J Qual Care Clin Outcomes

DOI

EISSN

2058-1742

Publication Date

December 19, 2025

Volume

11

Issue

8

Start / End Page

1421 / 1430

Location

England

Related Subject Headings

  • Secondary Prevention
  • Risk Assessment
  • Myocardial Infarction
  • Humans
  • Disease Management
  • Delphi Technique
  • Consensus
  • 4206 Public health
  • 3201 Cardiovascular medicine and haematology