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Mutual age-varying influences of binge drinking and cannabis use during emerging adulthood in the NCANDA cohort.

Publication ,  Journal Article
Waddell, JT; Brumback, T; Baker, FC; Cheek, S; Clark, DB; Goldston, DB; Grove, JL; Nagel, BJ; Nooner, KB; Pfefferbaum, A; Pohl, KM; Tapert, SF ...
Published in: Alcohol Clin Exp Res (Hoboken)
October 2025

BACKGROUND: Binge drinking peaks during emerging adulthood and is associated with negative developmental outcomes. Within-person changes in cannabis use have been shown to coincide with binge drinking; however, whether within-person changes in binge drinking and cannabis use prospectively predict one another and whether these relations vary by age remain unknown. The current study sought to fill these gaps. METHODS: Data come from National Consortium on Alcohol and Neurodevelopment (NCANDA) participants aged 18-25 years reporting alcohol and cannabis use (N = 526). Parallel-process state-trait mixed effect growth models tested whether: (1) binge drinking across emerging adulthood was correlated with cannabis use (random intercepts); (2) steeper growth in binge drinking across emerging adulthood correlated with growth in cannabis use (random slopes); and (3) age-specific, within-person changes in binge drinking/cannabis use reciprocally predicted one another. RESULTS: Across individuals, more frequent binge drinking was correlated with more frequent concurrent cannabis use, and steeper increases in binge drinking were correlated with steeper increases in cannabis use during emerging adulthood. Within-person changes in binge drinking and cannabis use covaried. Within-person increases in cannabis use predicted subsequent increases in binge drinking between ages 18 and 21 years but decreases in binge drinking between ages 24 and 25 years. Within-person changes in binge drinking did not predict subsequent changes in cannabis use during emerging adulthood. CONCLUSIONS: Changes in cannabis use coincided with changes in binge drinking, concurrently and subsequently, particularly between ages 18 and 21 years when changes in cannabis use predicted subsequent increases in binge drinking and ages 24 and 25 years when changes in cannabis use predicted decreases in subsequent binge drinking. Incorporating motivational approaches to reduce cannabis use in alcohol interventions may be efficacious in early emerging adulthood.

Duke Scholars

Published In

Alcohol Clin Exp Res (Hoboken)

DOI

EISSN

2993-7175

Publication Date

October 2025

Volume

49

Issue

10

Start / End Page

2239 / 2249

Location

United States

Related Subject Headings

  • Young Adult
  • Marijuana Use
  • Marijuana Smoking
  • Male
  • Humans
  • Female
  • Cohort Studies
  • Binge Drinking
  • Age Factors
  • Adult
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Waddell, J. T., Brumback, T., Baker, F. C., Cheek, S., Clark, D. B., Goldston, D. B., … Brown, S. A. (2025). Mutual age-varying influences of binge drinking and cannabis use during emerging adulthood in the NCANDA cohort. Alcohol Clin Exp Res (Hoboken), 49(10), 2239–2249. https://doi.org/10.1111/acer.70139
Waddell, Jack T., Ty Brumback, Fiona C. Baker, Shayna Cheek, Duncan B. Clark, David B. Goldston, Jeremy L. Grove, et al. “Mutual age-varying influences of binge drinking and cannabis use during emerging adulthood in the NCANDA cohort.Alcohol Clin Exp Res (Hoboken) 49, no. 10 (October 2025): 2239–49. https://doi.org/10.1111/acer.70139.
Waddell JT, Brumback T, Baker FC, Cheek S, Clark DB, Goldston DB, et al. Mutual age-varying influences of binge drinking and cannabis use during emerging adulthood in the NCANDA cohort. Alcohol Clin Exp Res (Hoboken). 2025 Oct;49(10):2239–49.
Waddell, Jack T., et al. “Mutual age-varying influences of binge drinking and cannabis use during emerging adulthood in the NCANDA cohort.Alcohol Clin Exp Res (Hoboken), vol. 49, no. 10, Oct. 2025, pp. 2239–49. Pubmed, doi:10.1111/acer.70139.
Waddell JT, Brumback T, Baker FC, Cheek S, Clark DB, Goldston DB, Grove JL, Nagel BJ, Nooner KB, Pfefferbaum A, Pohl KM, Sullivan EV, Tapert SF, Thompson WK, Brown SA. Mutual age-varying influences of binge drinking and cannabis use during emerging adulthood in the NCANDA cohort. Alcohol Clin Exp Res (Hoboken). 2025 Oct;49(10):2239–2249.

Published In

Alcohol Clin Exp Res (Hoboken)

DOI

EISSN

2993-7175

Publication Date

October 2025

Volume

49

Issue

10

Start / End Page

2239 / 2249

Location

United States

Related Subject Headings

  • Young Adult
  • Marijuana Use
  • Marijuana Smoking
  • Male
  • Humans
  • Female
  • Cohort Studies
  • Binge Drinking
  • Age Factors
  • Adult