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Artificial womb technologies - Innovation at the edge of viability: Ethical considerations.

Publication ,  Journal Article
Paul, J; De Bie, FR; Johnston, H; Antiel, RM
Published in: J Pediatr Surg
February 2026

Artificial womb technologies (AWT) represent true innovation, and a potential paradigm shift in neonatal care at the edge of viability. As AWT progresses from animal models to first-in-human trials, it raises complex ethical, legal, and societal questions. In this paper, we review the rationale for AWT in extremely premature infants as well as the ethical implications, organized in seven ethical domains: Beneficence and Harm; Parental Autonomy and Responsibility; Legal and Moral Status; Reproductive Rights; Justice and Access; Cultural and Societal Perspectives; and Research Ethics and Oversight. We conclude with a discussion of the next steps towards responsible clinical translation of AWT.

Duke Scholars

Published In

J Pediatr Surg

DOI

EISSN

1531-5037

Publication Date

February 2026

Volume

61

Issue

2

Start / End Page

162827

Location

United States

Related Subject Headings

  • Reproductive Rights
  • Pregnancy
  • Personal Autonomy
  • Pediatrics
  • Inventions
  • Infant, Newborn
  • Infant, Extremely Premature
  • Humans
  • Fetal Viability
  • Female
 

Citation

APA
Chicago
ICMJE
MLA
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Paul, J., De Bie, F. R., Johnston, H., & Antiel, R. M. (2026). Artificial womb technologies - Innovation at the edge of viability: Ethical considerations. J Pediatr Surg, 61(2), 162827. https://doi.org/10.1016/j.jpedsurg.2025.162827
Paul, Jennifer, Felix R. De Bie, Hannah Johnston, and Ryan M. Antiel. “Artificial womb technologies - Innovation at the edge of viability: Ethical considerations.J Pediatr Surg 61, no. 2 (February 2026): 162827. https://doi.org/10.1016/j.jpedsurg.2025.162827.
Paul J, De Bie FR, Johnston H, Antiel RM. Artificial womb technologies - Innovation at the edge of viability: Ethical considerations. J Pediatr Surg. 2026 Feb;61(2):162827.
Paul, Jennifer, et al. “Artificial womb technologies - Innovation at the edge of viability: Ethical considerations.J Pediatr Surg, vol. 61, no. 2, Feb. 2026, p. 162827. Pubmed, doi:10.1016/j.jpedsurg.2025.162827.
Paul J, De Bie FR, Johnston H, Antiel RM. Artificial womb technologies - Innovation at the edge of viability: Ethical considerations. J Pediatr Surg. 2026 Feb;61(2):162827.
Journal cover image

Published In

J Pediatr Surg

DOI

EISSN

1531-5037

Publication Date

February 2026

Volume

61

Issue

2

Start / End Page

162827

Location

United States

Related Subject Headings

  • Reproductive Rights
  • Pregnancy
  • Personal Autonomy
  • Pediatrics
  • Inventions
  • Infant, Newborn
  • Infant, Extremely Premature
  • Humans
  • Fetal Viability
  • Female