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Restricting choice of e-cigarette flavor and device type increases choices to use combusted cigarettes among adults who dual use both products: Results from a within-subjects randomized trial.

Publication ,  Journal Article
Rubenstein, D; Pacek, LR; Green, MJ; Sweitzer, MM; Kozink, R; Holloway, A; Donny, EC; Smith, TT; McClernon, FJ
Published in: Addict Behav
December 1, 2025

INTRODUCTION: Data from real-world e-cigarette (EC) flavor bans suggest that such bans may increase combusted cigarette (CC) use. However, experimental data are needed to better understand how EC characteristics affect EC appeal and CC use. METHODS: Participants were adults who used both CC and flavored EC. They made 10 choices per session between taking two puffs from an EC or CC (supplied by study) or abstaining. EC type was unblinded and varied across three counterbalanced sessions: 1) own device and flavor, 2) study device with a non-tobacco-flavored e-liquid, and 3) study device with a tobacco-flavored e-liquid. Analyses evaluated EC appeal and choices to use EC, CC, or abstain. RESULTS: Participants (n = 41) reported using CCs on 22.1 days/month and ECs on 26.9 days/month. Appeal of study EC was lower than participants' own EC, and participants made fewer choices for EC during tobacco-flavor EC versus own device sessions (p = 0.006). Relative to own device sessions, participants made a greater number of choices for CC when study EC were available (p's < 0.05), regardless of flavor. DISCUSSION: Regulators and public health officials should be aware that restricting EC characteristics such as device type and flavor may increase consumption of CC among people who use both products, especially people who find restricted EC less appealing than their own device. Findings are consistent with real-world sales data following EC flavor bans.

Duke Scholars

Published In

Addict Behav

DOI

EISSN

1873-6327

Publication Date

December 1, 2025

Volume

174

Start / End Page

108578

Location

England

Related Subject Headings

  • Substance Abuse
  • 5203 Clinical and health psychology
  • 5202 Biological psychology
  • 4206 Public health
  • 1701 Psychology
  • 1117 Public Health and Health Services
 

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Rubenstein, D., Pacek, L. R., Green, M. J., Sweitzer, M. M., Kozink, R., Holloway, A., … McClernon, F. J. (2025). Restricting choice of e-cigarette flavor and device type increases choices to use combusted cigarettes among adults who dual use both products: Results from a within-subjects randomized trial. Addict Behav, 174, 108578. https://doi.org/10.1016/j.addbeh.2025.108578
Rubenstein, Dana, Lauren R. Pacek, Michael J. Green, Maggie M. Sweitzer, Rachel Kozink, Alicia Holloway, Eric C. Donny, Tracy T. Smith, and F Joseph McClernon. “Restricting choice of e-cigarette flavor and device type increases choices to use combusted cigarettes among adults who dual use both products: Results from a within-subjects randomized trial.Addict Behav 174 (December 1, 2025): 108578. https://doi.org/10.1016/j.addbeh.2025.108578.
Rubenstein D, Pacek LR, Green MJ, Sweitzer MM, Kozink R, Holloway A, Donny EC, Smith TT, McClernon FJ. Restricting choice of e-cigarette flavor and device type increases choices to use combusted cigarettes among adults who dual use both products: Results from a within-subjects randomized trial. Addict Behav. 2025 Dec 1;174:108578.
Journal cover image

Published In

Addict Behav

DOI

EISSN

1873-6327

Publication Date

December 1, 2025

Volume

174

Start / End Page

108578

Location

England

Related Subject Headings

  • Substance Abuse
  • 5203 Clinical and health psychology
  • 5202 Biological psychology
  • 4206 Public health
  • 1701 Psychology
  • 1117 Public Health and Health Services