An Update to the Clinical Pharmacogenetics Implementation Consortium (CPIC) SLCO1B1 Allele Functionality Table Leveraging Evidence from Participants of Predominantly Sub-Saharan African Ancestry.

The Clinical Pharmacogenetics Implementation Consortium (CPIC) has formally updated the SLCO1B1 allele functionality table based on new evidence. Notably, the alleles studied (SLCO1B1 *9, *31, *41) are enriched in the genomes of patients historically excluded from pharmacogenomics research. This perspective illustrates how new evidence can advance clinical pharmacogenetics implementation guidelines incorporation in real time through collaboration with CPIC. Together, we can accelerate the translation of pharmacogenetics into a tool that truly improves health outcomes for everyone.

Duke Scholars

Author Deepak Voora Medicine, Cardiology