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Skin deep: Unconventional autophagy eats away TNF-driven skin inflammation.

Publication ,  Journal Article
Feng, Y; Chan, FK-M
Published in: Immunity
December 9, 2025

Tumor necrosis factor (TNF), type I interferons (IFNs), and autophagy are important biological processes, but their interactions in inflammation have not been explored. In this issue of Immunity, Priem et al. reveal that ATG9A-mediated autophagy curbs skin inflammation by suppressing STING activation and Z-DNA binding protein 1 (ZBP1)-dependent cell death.

Duke Scholars

Published In

Immunity

DOI

EISSN

1097-4180

Publication Date

December 9, 2025

Volume

58

Issue

12

Start / End Page

2920 / 2922

Location

United States

Related Subject Headings

  • Vesicular Transport Proteins
  • Tumor Necrosis Factor-alpha
  • Skin
  • Mice
  • Membrane Proteins
  • Interferon Type I
  • Inflammation
  • Immunology
  • Humans
  • DNA-Binding Proteins
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Feng, Y., & Chan, F.-M. (2025). Skin deep: Unconventional autophagy eats away TNF-driven skin inflammation. Immunity, 58(12), 2920–2922. https://doi.org/10.1016/j.immuni.2025.11.008
Feng, Ying, and Francis Ka-Ming Chan. “Skin deep: Unconventional autophagy eats away TNF-driven skin inflammation.Immunity 58, no. 12 (December 9, 2025): 2920–22. https://doi.org/10.1016/j.immuni.2025.11.008.
Feng Y, Chan FK-M. Skin deep: Unconventional autophagy eats away TNF-driven skin inflammation. Immunity. 2025 Dec 9;58(12):2920–2.
Feng, Ying, and Francis Ka-Ming Chan. “Skin deep: Unconventional autophagy eats away TNF-driven skin inflammation.Immunity, vol. 58, no. 12, Dec. 2025, pp. 2920–22. Pubmed, doi:10.1016/j.immuni.2025.11.008.
Feng Y, Chan FK-M. Skin deep: Unconventional autophagy eats away TNF-driven skin inflammation. Immunity. 2025 Dec 9;58(12):2920–2922.
Journal cover image

Published In

Immunity

DOI

EISSN

1097-4180

Publication Date

December 9, 2025

Volume

58

Issue

12

Start / End Page

2920 / 2922

Location

United States

Related Subject Headings

  • Vesicular Transport Proteins
  • Tumor Necrosis Factor-alpha
  • Skin
  • Mice
  • Membrane Proteins
  • Interferon Type I
  • Inflammation
  • Immunology
  • Humans
  • DNA-Binding Proteins