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A Randomized Controlled Trial of a Care Partner-Assisted Oral Hygiene Intervention for Persons With Mild Dementia

Publication ,  Conference
Wu, B; Finik, J; Mott, C; Poole, P; Bunn, M; Anderson, R; Plassman, B
Published in: Innovation in Aging
December 1, 2025

Oral hygiene contributes to oral health outcomes and quality of life. This study evaluates a care partner-assisted intervention to improve oral hygiene in community-dwelling older adults with mild dementia. We conducted a three-arm randomized controlled trial involving 60 participants with mild dementia and their care partners. Participants were randomized into three arms: (1) control (educational booklet only), (2) Treatment Group 1 (TG1: smart electronic toothbrush without coaching), and (3) Treatment Group 2 (TG2: smart electronic toothbrush plus personalized coaching). Plaque and gingival inflammation were assessed at baseline, 3 months, and 6 months using linear mixed models. All groups showed significant reductions in mean plaque and gingival inflammation from baseline. For plaque, significant reductions were observed at both 3 [β=-0.10 (95% CI, -0.15, -0.06)] and 6 months [β=-0.07 (95% CI, -0.12, -0.03)]. For gingival inflammation, significant reductions were observed at 3 months [β=-0.12 (95% CI, -0.19, -0.05)] but not at 6 months [β= -0.05 (95% CI, -0.12 to 0.02)]. In terms of absolute reduction at study follow up, TG2 showed the largest reduction from baseline in mean plaque [3 months: -0.19 TG2, -0.07 TG1, -0.06 control; 6 months -0.15 TG2, -0.07 TG1, -0.01 control] and gingival inflammation [3 months: -0.22 TG2, -0.07 TG1, -0.05 control; 6 months -0.16 TG2, -0.10 TG1, +0.11 control]. A care partner-assisted intervention may support oral health improvements in individuals with mild dementia, with potential sustained benefits. Larger studies with longer follow-up are needed to fully evaluate the efficacy of the intervention.

Duke Scholars

Published In

Innovation in Aging

DOI

EISSN

2399-5300

Publication Date

December 1, 2025

Volume

9

Issue

Supplement_2

Publisher

Oxford University Press (OUP)

Related Subject Headings

  • 3202 Clinical sciences
 

Citation

APA
Chicago
ICMJE
MLA
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Wu, B., Finik, J., Mott, C., Poole, P., Bunn, M., Anderson, R., & Plassman, B. (2025). A Randomized Controlled Trial of a Care Partner-Assisted Oral Hygiene Intervention for Persons With Mild Dementia. In Innovation in Aging (Vol. 9). Oxford University Press (OUP). https://doi.org/10.1093/geroni/igaf122.1026
Wu, Bei, Jackie Finik, Catharine Mott, Patricia Poole, Melanie Bunn, Ruth Anderson, and Brenda Plassman. “A Randomized Controlled Trial of a Care Partner-Assisted Oral Hygiene Intervention for Persons With Mild Dementia.” In Innovation in Aging, Vol. 9. Oxford University Press (OUP), 2025. https://doi.org/10.1093/geroni/igaf122.1026.
Wu B, Finik J, Mott C, Poole P, Bunn M, Anderson R, et al. A Randomized Controlled Trial of a Care Partner-Assisted Oral Hygiene Intervention for Persons With Mild Dementia. In: Innovation in Aging. Oxford University Press (OUP); 2025.
Wu, Bei, et al. “A Randomized Controlled Trial of a Care Partner-Assisted Oral Hygiene Intervention for Persons With Mild Dementia.” Innovation in Aging, vol. 9, no. Supplement_2, Oxford University Press (OUP), 2025. Crossref, doi:10.1093/geroni/igaf122.1026.
Wu B, Finik J, Mott C, Poole P, Bunn M, Anderson R, Plassman B. A Randomized Controlled Trial of a Care Partner-Assisted Oral Hygiene Intervention for Persons With Mild Dementia. Innovation in Aging. Oxford University Press (OUP); 2025.
Journal cover image

Published In

Innovation in Aging

DOI

EISSN

2399-5300

Publication Date

December 1, 2025

Volume

9

Issue

Supplement_2

Publisher

Oxford University Press (OUP)

Related Subject Headings

  • 3202 Clinical sciences